Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity

Published 2019 View Full Article

Authors

Keywords

topoisomerase, topoisomerase 2 cleavage complex, DNA double-strand breaks, cohesin, 3D chromatin organization, transcription, chromosomal translocations, proteasome, TDP2, quantitative modeling

Journal

MOLECULAR CELL

Volume 75, Issue 2, Pages 252-266.e8

Publisher

Elsevier BV

Online

2019-06-12

DOI

10.1016/j.molcel.2019.04.030

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Reprint

Contact the author

Create your own webinar

Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.

Create Now

Become a Peeref-certified reviewer

The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.

Get Started