Second Messenger cA4 Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path

Title
Second Messenger cA4 Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path
Authors
Keywords
type III-A CRISPR-Cas Csm, adenosine recognition specificity, ligand positioning in composite Palm pocket, ATP conversion into pppA, n, intermediates and cA, n, products, mechanistic insights into cA, 4, formation and release
Journal
MOLECULAR CELL
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2019-07-17
DOI
10.1016/j.molcel.2019.06.013

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