CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4 Cleavage with ApA>p Formation Terminating RNase Activity
Authors
Keywords
Type III-A CRISPR-Cas Csm, Csm6 CARF is a ring nuclease, Sequential cleavage bursts regulate RNase activity, A CARF histidine contributes to autoinhibition, Csm6 is an adenosine-specific RNase
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