Colorectal carcinoma with double somatic mismatch repair gene inactivation: clinical and pathological characteristics and response to immune checkpoint blockade
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Colorectal carcinoma with double somatic mismatch repair gene inactivation: clinical and pathological characteristics and response to immune checkpoint blockade
Authors
Keywords
-
Journal
MODERN PATHOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-07
DOI
10.1038/s41379-019-0289-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Using Somatic Mutations from Tumors to Classify Variants in Mismatch Repair Genes
- (2018) Brian H. Shirts et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Histology of colorectal adenocarcinoma with double somatic mismatch-repair mutations is indistinguishable from those caused by Lynch syndrome
- (2018) Jessica A. Hemminger et al. HUMAN PATHOLOGY
- Immunohistochemical null-phenotype for mismatch repair proteins in colonic carcinoma associated with concurrent MLH1 hypermethylation and MSH2 somatic mutations
- (2017) Tao Wang et al. Familial Cancer
- Recent discoveries in the molecular genetics of Lynch syndrome
- (2016) C. Richard Boland Familial Cancer
- Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors With 2 or More Somatic Mutations in Mismatch Repair Genes
- (2016) Stacey A. Cohen et al. GASTROENTEROLOGY
- Double somatic mutations in mismatch repair genes are frequent in colorectal cancer after Hodgkin's lymphoma treatment
- (2016) Lisanne S Rigter et al. GUT
- Morphological characterization of colorectal cancers in The Cancer Genome Atlas reveals distinct morphology–molecular associations: clinical and biological implications
- (2016) Jinru Shia et al. MODERN PATHOLOGY
- FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing
- (2016) Ronglai Shen et al. NUCLEIC ACIDS RESEARCH
- Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers
- (2015) Anne ML Jansen et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT)
- (2015) Donavan T. Cheng et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies
- (2014) S. Venderbosch et al. CLINICAL CANCER RESEARCH
- Biallelic MUTYH mutations can mimic Lynch syndrome
- (2014) Monika Morak et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- MLH1 promotor hypermethylation does not rule out a diagnosis of Lynch syndrome: a case report
- (2014) Victoria M. Raymond et al. Familial Cancer
- High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry
- (2014) Christophe Rosty et al. Familial Cancer
- Colon and Endometrial Cancers With Mismatch Repair Deficiency Can Arise From Somatic, Rather Than Germline, Mutations
- (2014) Sigurdis Haraldsdottir et al. GASTROENTEROLOGY
- Somatic aberrations of mismatch repair genes as a cause of microsatellite-unstable cancers
- (2014) Willemina RR Geurts-Giele et al. JOURNAL OF PATHOLOGY
- Somatic Mutations in MLH1 and MSH2 Are a Frequent Cause of Mismatch-Repair Deficiency in Lynch Syndrome-Like Tumors
- (2013) Arjen R. Mensenkamp et al. GASTROENTEROLOGY
- Somatic mosaicism and double somatic hits can lead to MSI colorectal tumors
- (2012) Isabelle Sourrouille et al. Familial Cancer
- Correlation of tumour BRAF mutations andMLH1methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification
- (2012) Michael T Parsons et al. JOURNAL OF MEDICAL GENETICS
- Predicting the Functional Effect of Amino Acid Substitutions and Indels
- (2012) Yongwook Choi et al. PLoS One
- Methylation Analysis of MLH1 Improves the Selection of Patients for Genetic Testing in Lynch Syndrome
- (2010) Lucía Pérez-Carbonell et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- A method and server for predicting damaging missense mutations
- (2010) Ivan A Adzhubei et al. NATURE METHODS
- The Clinical Phenotype of Lynch Syndrome Due to Germ-Line PMS2 Mutations
- (2008) Leigha Senter et al. GASTROENTEROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started