Review
Oncology
Gunel Guliyeva, Maria T. Huayllani, Daniel Boczar, Francisco R. Avila, Xiaona Lu, Antonio Jorge Forte
Summary: This review evaluated the impact of age on the development of BCRL. The majority of studies did not identify age as a risk factor for lymphedema development, although the level of evidence was low.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Medicine, General & Internal
Yuma Fuse, Ryo Karakawa, Tomoyuki Yano, Hidehiko Yoshimatsu
Summary: The study evaluated the efficacy of lymph-venous anastomosis (LVA) for breast cancer-related lymphoedema (BCRL) patients with a history of docetaxel use. Results showed that LVA was comparably effective for patients who had undergone docetaxel-based chemotherapy before or after axillary lymph node dissection (ALND).
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Oncology
Marisa Perdomo, Claire Davies, Kimberly Levenhagen, Kathryn Ryans, Laura Gilchrist
Summary: This study aimed to evaluate the impact of BCRL education content, modes, and timing on individuals diagnosed with breast cancer. The findings recommend individualized education using a multi-modal approach, repeated at multiple time points, and assessment of survivors' knowledge acquisition.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Review
Oncology
Jingru Bian, Aomei Shen, Wanwan Yang, Liyuan Zhang, Wanmin Qiang
Summary: This study conducted a systematic review on the financial toxicity of breast cancer-related lymphedema. The findings showed that the treatment costs for lymphedema were high and the severity of lymphedema was associated with greater financial burden. The government should improve the healthcare system and increase insurance coverage to alleviate this burden.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Nursing
Ling Wang, Yue Xian Shi, Ting Ting Wang, Ke Xin Chen, Shao Mei Shang
Summary: This systematic review provides evidence-based recommendations for resistance training in breast cancer-related lymphoedema (BCRL) and offers guidance for clinicians. Current guidelines and consensus documents need to be updated in terms of topics such as effectiveness of resistance training and resistance training outcome index.
JOURNAL OF CLINICAL NURSING
(2023)
Review
Pharmacology & Pharmacy
Hao Tian, Dandan Ma, Xuanni Tan, Wenting Yan, Xiujuan Wu, Cheng He, Ling Zhong, Yan Zhang, Bingjie Yu, Yi Zhang, Xiaowei Qi
Summary: Platinum derivatives and taxanes have demonstrated efficacy in treating TNBC, with their combination leading to reduced systemic toxicity and improved outcomes in both neoadjuvant and adjuvant settings. The sensitivity of BRCA1-mutated cells to taxanes remains a challenge, but recent evidence supports the benefit of combining carboplatin and paclitaxel for better pathological complete response in TNBC patients. Various clinical studies are ongoing to further explore the mechanisms and advantages of platinum and taxane-based chemotherapies in early TNBC.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Oncology
Maureen P. McEvoy, Ameer Gomberawalla, Mark Smith, Francesco M. Boccardo, Dennis Holmes, Risal Djohan, Paul Thiruchelvam, Suzanne Klimberg, Jill Dietz, Sheldon Feldman
Summary: Breast cancer-related lymphedema affects millions of patients worldwide. Prevention and treatment require a multidisciplinary team, emphasizing early detection and awareness of risk factors to reduce the progression of lymphedema. Treatment can be costly, time-consuming, and not always effective, therefore prevention is the ultimate goal.
FRONTIERS IN ONCOLOGY
(2022)
Review
Oncology
Aomei Shen, Wanmin Qiang, Liyuan Zhang, Jingru Bian, Fei Zhu, Zijuan Zhang, Qian Lu
Summary: The study identified innate personal trait-related risk factors for breast cancer-related lymphedema (BCRL), with some factors showing significant associations with BCRL incidence. The methodological quality and evidence quality of the study were generally low. Further well-designed studies and robust meta-analyses are needed to explore potential associations between behavioral, interpersonal, and environmental factors with BCRL.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Xiaozhen Liu, Kewang Sun, Hongjian Yang, Lingli Xia, Kefeng Lu, Xuli Meng, Yongfeng Li
Summary: This study aimed to identify intraoperative and preoperative risk factors of severe lymphedema and develop a nomogram for estimating the risk of severe lymphedema within 3 years of surgery. It was found that age, positive lymph nodes, interpectoral (Rotter's) lymph nodes (IPNs) dissection, and educational level were independent risk factors for severe lymphedema. A nomogram was developed by integrating these factors and showed moderate performance in predicting the risk of severe lymphedema within 3 years of surgery.
Review
Oncology
Aomei Shen, Xiaoxia Wei, Fei Zhu, Mengying Sun, Sangsang Ke, Wanmin Qiang, Qian Lu
Summary: This study aimed to evaluate currently available risk prediction models for breast cancer-related lymphedema (BCRL) and identify their limitations. The findings indicated that although these models showed moderate to good predictive performance, they were at high risk of bias and poorly reported. Therefore, none of these models are suitable for recommendation in clinical practice.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2023)
Review
Medicine, General & Internal
Xin-Yu Zhang, Quan Wang, Ke-Lu Yang, Dang Wei, Xiao-Nan Liu
Summary: Childhood cancer survivors are at high risk of cardiovascular diseases due to anticancer therapy-induced cardiotoxicity. However, there is sparse evidence on the prevention of anticancer therapy-induced cardiovascular disease. This systematic review aims to summarize the current prevention strategies for anticancer therapy-induced cardiotoxicity in childhood cancer survivors.
Review
Oncology
Elena Munoz-Gomez, Anna Arnal-Gomez, Alba Lopez Cascon, Gemma Espi-Lopez
Summary: The purpose of this review is to evaluate the efficacy of aquatic therapeutic exercise in female breast cancer survivors for improving fatigue, pain, lymphedema, and quality of life. A systematic literature review was conducted, and ten randomized controlled trials with 606 participants were included. The results suggest that aquatic therapeutic exercise is effective in reducing fatigue, pain, and improving quality of life, although the effects on lymphedema remain uncertain. The methodological quality of the studies was high, and no adverse effects were reported.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Surgery
Harm Winters, Hanneke J. P. Tielemans, Vera Paulus, Stefan Hummelink, Nicholas J. Slater, Dietmar J. O. Ulrich
Summary: Vascularized lymph node transfer (VLNT) is an effective technique for treating lymphedema in breast cancer patients. The current evidence suggests that VLNT can improve the volume differences between the arms and have a positive effect on patients' quality of life, reducing skin infections and the need for compression garment usage. The complication rate is low.
JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS
(2022)
Review
Dermatology
Julia A. Cook, Mithun Sinha, Mary Lester, Carla S. Fisher, Chandan K. Sen, Aladdin H. Hassanein
Summary: This article introduces the definition and impact of lymphedema, and proposes a treatment method called ILR, which can reduce the risk of lymphedema through prophylactic lymphovenous anastomosis. Lymphedema has significant effects on the quality of life and morbidity of patients, and ILR may be an effective prophylactic treatment method. Long-term studies are needed in the future to demonstrate the efficacy of ILR.
ADVANCES IN WOUND CARE
(2022)
Review
Medicine, General & Internal
Qiu Lin, Tong Yang, Jin Yongmei, Ye Mao Die
Summary: This study systematically reviewed and critically evaluated prediction models for breast cancer-related lymphedema. The findings revealed a high risk of bias in all models and highlighted the need for further research on the strength of predictors, external validation, and clinical application.
SYSTEMATIC REVIEWS
(2022)
