Article
Oncology
Zhouying Peng, Yumin Wang, Yaxuan Wang, Ruohao Fan, Kelei Gao, Hua Zhang, Weihong Jiang
Summary: This meta-analysis compared the efficacy of IMRT and ES for high T-stage recurrent NPC. Results suggest that ES may improve survival in recurrent NPC with rT3-4, with potentially fewer complications. More studies are needed to confirm these findings.
FRONTIERS IN ONCOLOGY
(2021)
Review
Oncology
Won Il Jang, Sunmi Jo, Ji Eun Moon, Sun Hyun Bae, Hee Chul Park
Summary: This study is the first systematic review and meta-analysis on the advantages of IMRT for hepatocellular carcinoma. Despite most patients being in advanced stages and using combined treatment, IMRT for HCC showed similar survival rates to existing radiotherapy modalities and relatively low toxicity.
Article
Oncology
Fen Xue, Xiaoshuang Niu, Chaosu Hu, Xiayun He
Summary: This study aimed to determine the long-term risk of second primary lung adenocarcinoma (SPLAC) in nasopharyngeal cancer (NPC) patients after intensity-modulated radiotherapy (IMRT). The results showed that the incidence of SPLAC in NPC patients after IMRT was similar to that of the normal population, and most cases were detected in early stages during follow-up, with good surgical efficacy.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Guanzhu Shen, Yinglin Peng, Jian Li, Haijun Wu, Guangshun Zhang, Chong Zhao, Xiaowu Deng
Summary: This study evaluated the incidence of hypothyroidism in patients with nasopharyngeal carcinoma after IMRT, finding that 34.8% of patients developed hypothyroidism 12 months after radiotherapy. The average thyroid dose and thyroid volume were identified as key factors affecting hypothyroidism, with an NTCP model constructed based on these factors showing good fit.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Yi-Jun Hua, Yan-Feng Ou-Yang, Xiong Zou, Le Xia, Dong-Hua Luo, Ming-Yuan Chen
Summary: Radiotherapy is crucial for nasopharyngeal carcinoma patients, with a typical treatment duration of six to six and a half weeks. Prolonged radiotherapy duration is associated with higher risk of distant metastasis and death, highlighting the importance of avoiding prolonged treatment to improve outcomes.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Lin Chen, Jing Li, Kunpeng Li, Jiang Hu, Qingjie Li, Chenglong Huang, Gaoyuan Wang, Na Liu, Linglong Tang
Summary: This study analyzed the probability of hearing impairment after radiotherapy for nasopharyngeal carcinoma and developed a predictive model, providing dose limitation suggestions to improve patients' quality of life.
RADIOTHERAPY AND ONCOLOGY
(2024)
Article
Oncology
Ruiping Zhai, Yingchen Lyu, Mengshan Ni, Fangfang Kong, Chengrun Du, Chaosu Hu, Hongmei Ying
Summary: The study aims to identify factors predicting the risk of hypothyroidism in nasopharyngeal carcinoma patients after intensity-modulated radiotherapy (IMRT). The findings suggest that younger age, female gender, and small thyroid volume are the most important factors predicting hypothyroidism risk. Thyroid volume Vt40 is a key parameter in predicting the risk of hypothyroidism after IMRT in nasopharyngeal carcinoma patients.
RADIATION ONCOLOGY
(2022)
Article
Oncology
You-Ping Liu, Yi-Hui Wen, Jun Tang, Yi Wei, Rui You, Xiao-Lin Zhu, Jian Li, Lin Chen, Li Ling, Ning Zhang, Xiong Zou, Yi-Jun Hua, You-Mou Chen, Lei Chen, Li-Xia Lu, Ming-Yuan Chen, Wei-Ping Wen
Summary: Surgery significantly improved overall survival compared with IMRT in patients with resectable locally recurrent NPC. ENPG could be considered as the standard treatment option for this patient population, although long-term follow-up is needed to further determine the efficacy and toxicity of this strategy.
Article
Oncology
De-Huan Xie, Zheng Wu, Wang-Zhong Li, Wan-Qin Cheng, Ya-Lan Tao, Lei Wang, Shao-Wen Lv, Fei-Fei Lin, Nian-Ji Cui, Chong Zhao, Jun Ma, Shao-Min Huang, Tai-Xiang Lu, Ya-Qian Han, Yong Su
Summary: Individualized CTV delineation in unilateral NPC leads to excellent long-term local control with limited out-of-field recurrences, reduced dose to tumor-contralateral organs, and mild late toxicities.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2022)
Article
Oncology
Xigang Fan, Yecai Huang, Peng Xu, Yanmei Min, Jie Li, Mei Feng, Guohui Xu, Jinyi Lang
Summary: This study aims to investigate the relationship between radiation-induced brainstem necrosis (RIBN) and radiation dose in patients with nasopharyngeal carcinoma (NPC). The analysis revealed that the incidence of RIBN is associated with higher radiation doses, with D-max being the most significant predictive factor. It is suggested that the maximum dose limit for the brainstem should be considered during treatment.
Article
Medicine, General & Internal
Austin J. Iovoli, Lauren Turecki, Michelle L. Qiu, Michael Khan, Kelsey Smith, Han Yu, Sung Jun Ma, Mark K. Farrugia, Anurag K. Singh
Summary: Oral mucositis is a common adverse effect in head and neck cancer patients receiving radiation therapy. This study aimed to investigate the associations between the severity of oral mucositis and clinical outcomes and quality of life. The results showed that severe oral mucositis was associated with feeding tube placement, hospitalization, opiate use, and weight loss.
Article
Oncology
Qiaojuan Guo, Nan Xiao, Hanchuan Xu, Jingfeng Zong, Youping Xiao, Tianzhu Lu, Yun Xu, Bingyi Wang, Bijuan Chen, Jianji Pan, Shaojun Lin
Summary: This study investigated the feasibility of level Ib sparing in selected nasopharyngeal carcinoma patients during intensity-modulated radiation therapy based on the International Guideline. The results showed that level Ib-sparing IMRT is safe and feasible for patients who meet certain criteria.
RADIOTHERAPY AND ONCOLOGY
(2022)
Article
Oncology
Cem Onal, Sezin Yuce Sari, Guler Yavas, Ezgi Oymak, Sumerya Duru Birgi, Ecem Yigit, Ozan Cem Guler, Melis Gultekin, Serap Akyurek, Ferah Yildiz
Summary: In this study, EC patients treated with IMRT showed comparable clinical outcomes but lower incidence of GI toxicities compared to those treated with 3DCRT.
Article
Otorhinolaryngology
Jing-Jin Weng, Jia-Zhang Wei, Min Li, Le-Ping Ning, Fei Liu, Yun-Zhong Wei, Wei-Ming Xiong, Ben-Jian Zhang, Jin-Long Lu, He Jiang, Qiu-Tian Lu, Shen-Hong Qu
Summary: This study aimed to investigate the effect of hypothyroidism and thyroxine replacement therapy on the prognosis of nasopharyngeal carcinoma (NPC) patients. The results showed that patients with hypothyroidism had better survival rates. Hypothyroidism was identified as a positive independent prognostic factor. Thyroxine replacement therapy did not negatively affect the survival rates of these patients.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Article
Otorhinolaryngology
Xixi Liu, Bian Wu, Jing Huang, You Qin, Zhanjie Zhang, Liangliang Shi, Xiaohua Hong, Qian Ding, Gang Peng, Kunyu Yang
Summary: This study aims to identify tumor factors associated with in-field failure in patients with nasopharyngeal carcinoma (NPC) receiving intensity-modulated radiotherapy (IMRT). The results showed that in-field failure was the major pattern of recurrence in NPC patients. Large tumor volume, nonkeratinizing differentiated carcinoma, and cervical nodal necrosis were independent tumor factors associated with in-field failure.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Letter
Otorhinolaryngology
Meng-Si Luo, Guan-Jiang Huang
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Letter
Otorhinolaryngology
Guan-Jiang Huang
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Letter
Otorhinolaryngology
Guan-Jiang Huang
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Letter
Otorhinolaryngology
Meng-Si Luo, Guan-Jiang Huang
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Letter
Gastroenterology & Hepatology
Meng-Si Luo, Guan-Jiang Huang
Letter
Otorhinolaryngology
Guan-Jiang Huang
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Letter
Otorhinolaryngology
Guan-Jiang Huang
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Letter
Otorhinolaryngology
Guan-Jiang Huang, Shao-Hua Li, Chao-Qing Long, Zhi-Jun Fan
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Letter
Otorhinolaryngology
Guan-Jiang Huang, Bao-Rui Lin, Zhi-Jun Fan, Biao-Qing Lu
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Letter
Otorhinolaryngology
Guan-Jiang Huang, Chao-Qing Long, Shao-Hua Li, Zhi-Jun Fan
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Otorhinolaryngology
Guan-Jiang Huang, Meng-Si Luo, Hong-Bing Liu
Summary: The study compared the overall survival (OS) and cancer-specific survival (CSS) for T1aN0M0 glottic cancer patients who underwent laser surgery (LS) or radiation (RT) using population-based analysis and meta-analysis. The results indicated that patients who underwent LS had better OS and CSS compared to those who underwent RT. More randomized controlled trials are needed to confirm these findings.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Letter
Medicine, Research & Experimental
GUAN-JIANG HUANG
Article
Otorhinolaryngology
Guan-Jiang Huang, Ming Chen
Summary: This study aims to construct a dynamic prognostic model for predicting the cancer-specific survival of patients with T1aN0M0 glottic cancer. The results identified age, marital status, grade, primary site surgery, and chemotherapy as independent prognostic factors. The model showed excellent predictive accuracy and value in clinical decision-making.
CLINICAL OTOLARYNGOLOGY
(2023)
Article
Otorhinolaryngology
Guan-Jiang Huang, Zi-Qing Chen, Zhi-Jun Fan, Shao-Hua Li
Summary: This study applies Mendelian randomization method to assess the causal relationship between peripheral blood eosinophils and nasal polyps. The findings suggest a significant causal effect of peripheral blood eosinophils on the increased risk of nasal polyps.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)