Towards High-Throughput Chemobehavioural Phenomics in Neuropsychiatric Drug Discovery
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Towards High-Throughput Chemobehavioural Phenomics in Neuropsychiatric Drug Discovery
Authors
Keywords
-
Journal
Marine Drugs
Volume 17, Issue 6, Pages 340
Publisher
MDPI AG
Online
2019-06-07
DOI
10.3390/md17060340
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Integrative whole-brain neuroscience in larval zebrafish
- (2018) Gilles C .Vanwalleghem et al. CURRENT OPINION IN NEUROBIOLOGY
- Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery
- (2018) Michele Perni et al. JOURNAL OF NEUROSCIENCE METHODS
- Planarian stem cell niche, the challenge for understanding tissue regeneration
- (2018) Leonardo Rossi et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Planarian regeneration as a model of anatomical homeostasis: Recent progress in biophysical and computational approaches
- (2018) Michael Levin et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- C. elegans as a model in developmental neurotoxicology
- (2018) Joanna A. Ruszkiewicz et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Multidimensional chemobehavior analysis of flavonoids and neuroactive compounds in zebrafish
- (2018) Sean M. Bugel et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- A high-throughput approach to identify specific neurotoxicants / developmental toxicants in human neuronal cell function assays
- (2018) Johannes Delp ALTEX-Alternatives to Animal Experimentation
- Effects of ethanol on negative phototaxis and motility in brown planarians (Dugesia tigrina)
- (2018) Tom Byrne NEUROSCIENCE LETTERS
- The Cellular and Molecular Basis for Planarian Regeneration
- (2018) Peter W. Reddien CELL
- A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia
- (2018) Anabel Perez-Gomez et al. Nature Communications
- Effects of low concentrations of psychiatric drugs (carbamazepine and fluoxetine) on the freshwater planarian, Schmidtea mediterranea
- (2018) Pearl U. Ofoegbu et al. CHEMOSPHERE
- Axon regeneration in C. elegans: Worming our way to mechanisms of axon regeneration
- (2017) Alexandra B. Byrne et al. EXPERIMENTAL NEUROLOGY
- Video-rate volumetric functional imaging of the brain at synaptic resolution
- (2017) Rongwen Lu et al. NATURE NEUROSCIENCE
- Opportunities and challenges in phenotypic drug discovery: an industry perspective
- (2017) John G. Moffat et al. NATURE REVIEWS DRUG DISCOVERY
- A quantitative approach to neuropsychiatry: The why and the how
- (2017) Martien J. Kas et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Pharmacogenetics of antidepressant response: A polygenic approach
- (2017) Judit García-González et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Dissociation of place preference and tolerance responses to sucrose using a dopamine antagonist in the planarian
- (2017) Rafat A. Mohammed Jawad et al. PSYCHOPHARMACOLOGY
- Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
- (2017) Ariane-Saskia Ries et al. Nature Communications
- Nervous system development and regeneration in freshwater planarians
- (2017) Kelly G. Ross et al. Wiley Interdisciplinary Reviews-Developmental Biology
- A Brain Unfixed: Unlimited Neurogenesis and Regeneration of the Adult Planarian Nervous System
- (2017) David D. R. Brown et al. Frontiers in Neuroscience
- A Millifluidic System for Analysis of Daphnia magna Locomotory Responses to Water-born Toxicants
- (2017) Yushi Huang et al. Scientific Reports
- Automatic multiple zebrafish larvae tracking in unconstrained microscopic video conditions
- (2017) Xiaoying Wang et al. Scientific Reports
- Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology
- (2016) Matthew N. McCarroll et al. ACS Chemical Biology
- Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds
- (2016) Giancarlo Bruni et al. Nature Chemical Biology
- Cotinine antagonizes the behavioral effects of nicotine exposure in the planarian Girardia tigrina
- (2016) Daniel J. Bach et al. NEUROSCIENCE LETTERS
- Enabling sub-lethal behavioral ecotoxicity biotests using microfluidic Lab-on-a-Chip technology
- (2016) Yushi Huang et al. SENSORS AND ACTUATORS B-CHEMICAL
- In vivo phenotypic drug discovery: applying a behavioral assay to the discovery and optimization of novel antipsychotic agents
- (2016) Liming Shao et al. MedChemComm
- Vertically- and horizontally-transmitted memories – the fading boundaries between regeneration and inheritance in planaria
- (2016) Moran Neuhof et al. Biology Open
- 15 years of zebrafish chemical screening
- (2015) Andrew J Rennekamp et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Improving drug discovery with high-content phenotypic screens by systematic selection of reporter cell lines
- (2015) Jungseog Kang et al. NATURE BIOTECHNOLOGY
- Social feeding in Caenorhabditis elegans is modulated by antipsychotic drugs and calmodulin and may serve as a protophenotype for asociality
- (2015) Donard S. Dwyer et al. NEUROPHARMACOLOGY
- Whole-brain calcium imaging with cellular resolution in freely behavingCaenorhabditis elegans
- (2015) Jeffrey P. Nguyen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Freshwater Planarians as an Alternative Animal Model for Neurotoxicology
- (2015) Danielle Hagstrom et al. TOXICOLOGICAL SCIENCES
- Planarian shows decision-making behavior in response to multiple stimuli by integrative brain function
- (2015) Takeshi Inoue et al. Zoological Letters
- Ethanol and cocaine: Environmental place conditioning, stereotypy, and synergism in planarians
- (2014) Christopher S. Tallarida et al. ALCOHOL
- A Framework for Studying Emotions across Species
- (2014) David J. Anderson et al. CELL
- Fishing on chips: Up-and-coming technological advances in analysis of zebrafish andXenopusembryos
- (2014) Feng Zhu et al. CYTOMETRY PART A
- Worming our way to novel drug discovery with the Caenorhabditis elegans proteostasis network, stress response and insulin-signaling pathways
- (2014) Linda P O’Reilly et al. Expert Opinion on Drug Discovery
- Polypharmacology: Challenges and Opportunities in Drug Discovery
- (2014) Andrew Anighoro et al. JOURNAL OF MEDICINAL CHEMISTRY
- Thermosensory Signaling by TRPM Is Processed by Brain Serotonergic Neurons to Produce Planarian Thermotaxis
- (2014) T. Inoue et al. JOURNAL OF NEUROSCIENCE
- Identification of Marine Neuroactive Molecules in Behaviour-Based Screens in the Larval Zebrafish
- (2014) Si-Mei Long et al. Marine Drugs
- Molecular psychiatry of zebrafish
- (2014) A M Stewart et al. MOLECULAR PSYCHIATRY
- Zebrafish as an emerging model for studying complex brain disorders
- (2014) Allan V. Kalueff et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish
- (2014) Giancarlo Bruni et al. Frontiers in Pharmacology
- Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans
- (2014) Limin Hao et al. Jove-Journal of Visualized Experiments
- Worming Our Way to Alzheimer’s Disease Drug Discovery
- (2013) Sangeetha Iyer et al. BIOLOGICAL PSYCHIATRY
- Phenotypic screens as a renewed approach for drug discovery
- (2013) Wei Zheng et al. DRUG DISCOVERY TODAY
- An automated training paradigm reveals long-term memory in planarians and its persistence through head regeneration
- (2013) T. Shomrat et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Genetics of bipolar disorder
- (2013) Nick Craddock et al. LANCET
- High-throughput imaging of neuronal activity in Caenorhabditis elegans
- (2013) J. Larsch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for Multiple Genetic Factors Underlying DSM-IV Criteria for Major Depression
- (2013) Kenneth S. Kendler et al. JAMA Psychiatry
- A strategy for developing new treatment paradigms for neuropsychiatric and neurocognitive symptoms in Alzheimer’s disease
- (2013) Hugo Geerts et al. Frontiers in Pharmacology
- Dopamine D2 Receptor Antagonism Suppresses Tau Aggregation and Neurotoxicity
- (2012) Allyson V. McCormick et al. BIOLOGICAL PSYCHIATRY
- Pathways to new drug discovery in neuropsychiatry
- (2012) Michael Berk BMC Medicine
- Modern Phenotypic Drug Discovery Is a Viable, Neoclassic Pharma Strategy
- (2012) Jonathan A. Lee et al. JOURNAL OF MEDICINAL CHEMISTRY
- Automated high-throughput neurophenotyping of zebrafish social behavior
- (2012) Jeremy Green et al. JOURNAL OF NEUROSCIENCE METHODS
- Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology
- (2012) David Kokel et al. TRENDS IN BIOTECHNOLOGY
- Wormometry-on-a-chip: Innovative technologies for in situ analysis of small multicellular organisms
- (2011) Donald Wlodkowic et al. CYTOMETRY PART A
- Nicotine behavioral pharmacology: Clues from planarians
- (2011) Scott M. Rawls et al. DRUG AND ALCOHOL DEPENDENCE
- Regeneration of dopaminergic neurons after 6-hydroxydopamine-induced lesion in planarian brain
- (2011) Kaneyasu Nishimura et al. JOURNAL OF NEUROCHEMISTRY
- Chemical informatics and target identification in a zebrafish phenotypic screen
- (2011) Christian Laggner et al. Nature Chemical Biology
- High-throughput behavioral analysis in C. elegans
- (2011) Nicholas A Swierczek et al. NATURE METHODS
- Three-Dimensional Neurophenotyping of Adult Zebrafish Behavior
- (2011) Jonathan Cachat et al. PLoS One
- The Zebrafish Neurophenome Database (ZND): A Dynamic Open-Access Resource for Zebrafish Neurophenotypic Data
- (2011) Evan Kyzar et al. Zebrafish
- Swimming into the Future of Drug Discovery:In VivoChemical Screens in Zebrafish
- (2010) Teresa V. Bowman et al. ACS Chemical Biology
- Research Domain Criteria (RDoC): Toward a New Classification Framework for Research on Mental Disorders
- (2010) Thomas Insel et al. AMERICAN JOURNAL OF PSYCHIATRY
- Evolution and regeneration of the planarian central nervous system
- (2010) Yoshihiko Umesono et al. DEVELOPMENT GROWTH & DIFFERENTIATION
- The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform
- (2010) Sunita J. Shukla et al. DRUG DISCOVERY TODAY
- Live imaging of apoptotic cells in zebrafish
- (2010) Tjakko J. van Ham et al. FASEB JOURNAL
- The Caenorhabiditis elegans model as a reliable tool in neurotoxicology
- (2010) Daiana Avila et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- An elegant mind: Learning and memory in Caenorhabditis elegans
- (2010) E. L. Ardiel et al. LEARNING & MEMORY
- Fishing for neuroactive compounds
- (2010) Jeremy L Jenkins et al. Nature Chemical Biology
- Rapid behavior-based identification of neuroactive small molecules in the zebrafish
- (2010) David Kokel et al. Nature Chemical Biology
- High-throughput in vivo vertebrate screening
- (2010) Carlos Pardo-Martin et al. NATURE METHODS
- Phenomics: the next challenge
- (2010) David Houle et al. NATURE REVIEWS GENETICS
- Transgenic Zebrafish as a Novel Animal Model to Study Tauopathies and Other Neurodegenerative Disorders in vivo
- (2010) Dominik Paquet et al. Neurodegenerative Diseases
- Microelectrode arrays: A physiologically based neurotoxicity testing platform for the 21st century☆
- (2010) Andrew F.M. Johnstone et al. NEUROTOXICOLOGY
- A Second-Generation Device for Automated Training and Quantitative Behavior Analyses of Molecularly-Tractable Model Organisms
- (2010) Douglas Blackiston et al. PLoS One
- Lost in Translation: Neuropsychiatric Drug Development
- (2010) R. E. Becker et al. Science Translational Medicine
- Zebrafish: A Complete Animal Model for In Vivo Drug Discovery and Development
- (2009) Chiranjib Chakraborty et al. CURRENT DRUG METABOLISM
- Microfluidics for the analysis of behavior, nerve regeneration, and neural cell biology in C. elegans
- (2009) Adela Ben-Yakar et al. CURRENT OPINION IN NEUROBIOLOGY
- Simple vertebrate models for chemical genetics and drug discovery screens: Lessons from zebrafish andXenopus
- (2009) Grant N. Wheeler et al. DEVELOPMENTAL DYNAMICS
- Challenges in the Search for Drugs to Treat Central Nervous System Disorders
- (2009) S. J. Enna et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Lifespan-on-a-chip: microfluidic chambers for performing lifelong observation of C. elegans
- (2009) S. Elizabeth Hulme et al. LAB ON A CHIP
- Caenorhabditis elegans in Parkinson's Disease Drug Discovery: Addressing an Unmet Medical Need
- (2009) R. Nass et al. MOLECULAR INTERVENTIONS
- Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression
- (2009) Marlon Stoeckius et al. NATURE METHODS
- Shared genetics of bipolar disorder and schizophrenia
- (2009) James B. Potash et al. Nature Reviews Neurology
- Zebrafish: an emerging technology forin vivopharmacological assessment to identify potential safety liabilities in early drug discovery
- (2008) T P Barros et al. BRITISH JOURNAL OF PHARMACOLOGY
- Neuropharmacology and behavior in planarians: Translations to mammals
- (2008) Francesca R. Buttarelli et al. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
- Automated scoring of fear-related behavior using EthoVision software
- (2008) Jon Pham et al. JOURNAL OF NEUROSCIENCE METHODS
- Organization of the nervous system in the model planarian Schmidtea mediterranea: An immunocytochemical study
- (2008) Francesc Cebrià NEUROSCIENCE RESEARCH
- Functional and developmental analysis of the blood–brain barrier in zebrafish
- (2007) Jae-Yeon Jeong et al. BRAIN RESEARCH BULLETIN
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now