4.7 Article

Cerium, gallium and zinc containing mesoporous bioactive glass coating deposited on titanium alloy

Journal

APPLIED SURFACE SCIENCE
Volume 378, Issue -, Pages 216-223

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.apsusc.2016.03.209

Keywords

Mesoporous bioactive glass with Ce2O3; Ga2O3 or ZnO; Ti6Al4 V substrate; Polycaprolactone; Dip coating; In vitro bioactivity

Funding

  1. European Social Fund

Ask authors/readers for more resources

Surface modification is one of the methods for improving the performance of medical implants in biological environment. In this study, cerium, gallium and zinc substituted 80%SiO2-15%CaO-5%P2O5 mesoporous bioactive glass (MBG) in combination with polycaprolactone (PCL) were coated over Ti6Al4V substrates by dip-coating method in order to obtain an inorganic organic hybrid coating (MBG-PCL). Structural characterization was performed using XRD, nitrogen adsorption, SEM-EDXS, FTIR. The MBG-PCL coating uniformly covered the substrate with the thickness found to be more than 1 pin. Glass and polymer phases were detected in the coating along with the presence of biologically potent elements cerium, gallium and zinc. In addition, in vitro bioactivity was investigated by soaking the coated samples in simulated body fluid (SBF) for up to 30 days at 37 degrees C. The apatite-like layer was monitored by FTIR, SEM-EDXS and ICP measurements and it formed in all the samples within 15 days except zinc samples. In this way, an attempt was made to develop a new biomaterial with improved in vitro bioactive response due to bioactive glass coating and good mechanical strength of Ti6Al4V alloy along with inherent biological properties of cerium, gallium and zinc. (C) 2016 Elsevier B.V. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Chemistry, Physical

Investigating the Effect of Smoke Treatment on Hygroscopic Characteristics of Bamboo by FTIR and Raman Spectroscopy

Raviduth Ramful, Thefye P. M. Sunthar, Elia Marin, Wenliang Zhu, Giuseppe Pezzotti

Summary: This study investigated the effect of treatment modification, particularly smoke treatment, on the hygroscopic nature of bamboo using Raman and FTIR spectroscopic techniques. The results showed that smoke treatment caused changes in the chemical structure of bamboo and affected its water-repellency. Additionally, smoke treatment increased the lignin content of bamboo, resulting in increased hardness.

MATERIALS (2022)

Article Biochemistry & Molecular Biology

Three-Dimensional Culture of Cartilage Tissue on Nanogel-Cross-Linked Porous Freeze-Dried Gel Scaffold for Regenerative Cartilage Therapy: A Vibrational Spectroscopy Evaluation

Tetsuya Adachi, Nao Miyamoto, Hayata Imamura, Toshiro Yamamoto, Elia Marin, Wenliang Zhu, Miyuki Kobara, Yoshihiro Sowa, Yoshiro Tahara, Narisato Kanamura, Kazunari Akiyoshi, Osam Mazda, Ichiro Nishimura, Giuseppe Pezzotti

Summary: This study presents the vibrational characterizations of a nanogel-cross-linked porous freeze-dried gel scaffold for tissue engineering and regenerative therapy. The results demonstrate that this scaffold can effectively stimulate cartilage formation, improve cartilage matrix quality, and reveal the underlying mechanisms behind its superior performance through cell/scaffold interaction. Additionally, the study highlights the novelty of Raman spectroscopy as a non-destructive evaluation method and reveals the physiological mechanisms behind improved chondrocyte performance.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Chemistry, Medicinal

Raman Fingerprints of the SARS-CoV-2 Delta Variant and Mechanisms of Its Instantaneous Inactivation by Silicon Nitride Bioceramics

Giuseppe Pezzotti, Eriko Ohgitani, Yuki Fujita, Hayata Imamura, Masaharu Shin-Ya, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Elia Marin, Wenliang Zhu, Ichiro Nishimura, Osam Mazda

Summary: Raman spectroscopy revealed key mutations and structural differences in the molecular structure of the SARS-CoV-2 Delta variant compared to the Kappa variant. The hydrolytic reactions on the surface of silicon nitride bioceramics induced instantaneous inactivation of both variants. Contact with the bioceramics also led to post-translational modifications of spike residues and oxidation of RNA purines. Si3N4 bioceramics proved to be a safe and effective material for environmental sanitation.

ACS INFECTIOUS DISEASES (2022)

Article Engineering, Biomedical

Raman Analyses of Laser Irradiation-Induced Microstructural Variations in Synthetic Hydroxyapatite and Human Teeth

Hayata Imamura, Wenliang Zhu, Tetsuya Adachi, Noriko Hiraishi, Elia Marin, Nao Miyamoto, Toshiro Yamamoto, Narisato Kanamura, Giuseppe Pezzotti

Summary: This study examined the effects of laser irradiation treatment on human teeth enamel and synthetic hydroxyapatite (HAp) using Raman microprobe spectroscopy, and found that laser irradiation can modify the stoichiometry, microstructure, crystallographic defects, and hardness of the materials. These modifications depend on both laser power and the initial nonstoichiometric structure, indicating the occurrence of distinct reactions and structural reconstruction.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2022)

Article Biochemistry & Molecular Biology

In Situ Raman Analysis of Biofilm Exopolysaccharides Formed in Streptococcus mutans and Streptococcus sanguinis Commensal Cultures

Giuseppe Pezzotti, Satomi Ofuji, Hayata Imamura, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Eriko Ohgitani, Elia Marin, Wenliang Zhu, Osam Mazda, Azusa Togo, Satoshi Kimura, Tadahisa Iwata, Hideki Shiba, Kazuhisa Ouhara, Takashi Aoki, Toshihisa Kawai

Summary: This study investigated the mechanisms of competition/coexistence between Streptococcus sanguinis and Streptococcus mutans using quantitative Raman spectroscopy and imaging. The results suggest that the two species engage in antagonistic interactions and that Streptococcus sanguinis acts to disrupt the biofilm constructed by Streptococcus mutans. The main chemical weapon used by Streptococcus sanguinis in coculture is the secretion of oxygen radicals.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Article Chemistry, Multidisciplinary

Effect of Carbonate Source on the Dehydrofluorination Process in Polyvinylidene Fluoride/Alkali Metal Carbonate Composites

Wenliang Zhu, Kohei Okada, Naoki Hoshida, Yumi Yoshida, Alessandro Martucci, Jiliang Zhu, Elia Marin, Giuseppe Pezzotti

Summary: In this study, Raman and X-ray photoelectron spectroscopies were used to analyze the compositional and structural variations of activated carbon (AC) generated from different carbonate sources in three types of systems, PVDF/M2CO3 (M = Li, Na, and K). The results show that the structure of AC strongly depends on the type and content of the initial carbonate, which is determined by practical dehydrofluorination reactions and oxygen incorporation in AC. This study provides insights into the PVDF dehydrofluorination process and the formation of activated carbon, contributing to optimizing the material performance of percolative composites for flexible energy storage applications.

ACS OMEGA (2023)

Article Materials Science, Multidisciplinary

Particulate reinforced bone cements: The potential antibacteric role of nitrides

Elia Marin, Francesco Boschetto, Taigi Honma, Qing Yang, Obinna M. Ajunwa, Enrico Marsili, Wenliang Zhu, Giuseppe Pezzotti

Summary: The use of silicon nitride (Si3N4) ceramics as bioactive structural materials has become popular due to their ability to stimulate cell proliferation and fight pathogens. However, the brittleness and high production costs of silicon nitride limit its applications. This study investigates the addition of Si3N4 particles to Poly(methyl met-achylate) (PMMA) bone cements to examine their impact on mechanical and antibacterial properties. The results show that the antibacterial effects of Si3N4 increase with the ceramic fraction and decrease with the mesh size of the powders. Additionally, smaller particles at lower concentrations act as a mechanical reinforcement, increasing the composite's ultimate tensile strength by approximately 10%.

MATERIALIA (2023)

Article Biochemistry & Molecular Biology

Raman Multi-Omic Snapshot and Statistical Validation of Structural Differences between Herpes Simplex Type I and Epstein-Barr Viruses

Giuseppe Pezzotti, Eriko Ohgitani, Hayata Imamura, Saki Ikegami, Masaharu Shin-Ya, Tetsuya Adachi, Keiji Adachi, Toshiro Yamamoto, Narisato Kanamura, Elia Marin, Wenliang Zhu, Koichiro Higasa, Yoshiki Yasukochi, Kazu Okuma, Osam Mazda

Summary: Raman spectroscopy was used to investigate structural differences between HSV-1 and EBV. The results showed significant differences in structure, mainly attributed to the presence of carbohydrates in the glycoproteins of EBV virions. The Raman spectra also revealed variations in specific tyrosine and tryptophan bands, which were sensitive to the pH at the virion/environment interface. This study confirms the importance of Raman spectroscopy in addressing structural questions in virology and differentiating between virus types and strains.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Article Biochemistry & Molecular Biology

Instantaneous Inactivation of Herpes Simplex Virus by Silicon Nitride Bioceramics

Giuseppe Pezzotti, Eriko Ohgitani, Saki Ikegami, Masaharu Shin-Ya, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Elia Marin, Wenliang Zhu, Kazu Okuma, Osam Mazda

Summary: Hydrolytic reactions on the surface of Si3N4 bioceramic can instantaneously inactivate HHV-1 due to the direct reaction between ammonia and its nitrogen radical byproducts produced during Si3N4 hydrolysis and viral proteins, leading to irreversible damage to the virus DNA and structure.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Article Materials Science, Multidisciplinary

The role of Y2O3 in the bioactivity of YSZ/PLLA composites

Elia Marin, Giada Bassi, Orion Yoshikawa, Francesco Boschetto, Wenliang Zhu, Arianna Rossi, Alex Lanzutti, Huaizhong Xu, Monica Montesi, Silvia Panseri, Giuseppe Pezzotti

Summary: This study demonstrates the bioactivity of yttria stabilized zirconia ceramics in dental implantology, showing that they do not affect cell adhesion and can stimulate cell proliferation. The presence of a higher content of yttria enhances cell proliferation.

JOURNAL OF MATERIALS SCIENCE (2023)

Article Food Science & Technology

Raman Multi-Omic Snapshots of Koshihikari Rice Kernels Reveal Important Molecular Diversities with Potential Benefits in Healthcare

Giuseppe Pezzotti, Yusuke Tsubota, Wenliang Zhu, Elia Marin, Takehiro Masumura, Takuya Kobayashi, Tetsuya Nakazaki

Summary: This study utilizes quantitative algorithms of Raman spectroscopy to assess the nutritional quality of individual kernels of Japanese short-grain rice. It reveals wide distributions of nutritional parameters and suggests that genetic classifications cannot capture omic fluctuations. The possibility of collecting Raman multi-omic snapshots allows for the automatic differentiation of kernels, aiding in the formulation of functional foods and modulation of the intestinal microbiota.

FOODS (2023)

Article Chemistry, Analytical

Dental proteomic analyses and Raman spectroscopy for the estimation of the biological sex and age of human remains from the Greek cemetery of San Giorgio Extra, Reggio Calabria (Italy)

Enrico Greco, Andrea Maria Gennaro, Dario Piombino-Mascali, Daniela Costanzo, Simona Accardo, Sabina Licen, Pierluigi Barbieri, Stefano Fornasaro, Sabrina Semeraro, Elia Marin, Sara Signoretti, Caterina Gabriele, Marco Gaspari

Summary: This study created a new and reliable protocol for sex and age estimation of deceased individuals in a Greek cemetery using proteomic analyses, archaeological evidence, and anthropological data, as well as Raman spectroscopy for age estimation. The results from different approaches were congruent for the majority of individuals, and the proteomic analysis provided a faster protocol and potential scalability for lower sample amounts.

MICROCHEMICAL JOURNAL (2023)

Article Engineering, Biomedical

Forged to heal: The role of metallic cellular solids in bone tissue engineering

Elia Marin

Summary: Metallic cellular solids, made of biocompatible alloys, have gained attention for their mechanical strength, reliability, and biocompatibility. The design and material chemistry of metallic cellular solids play crucial roles in their performance. Various techniques are utilized for producing metallic biomedical cellular solids, each offering distinct advantages and drawbacks. Metallic cellular solids are superior to their ceramic and polymeric counterparts in most load bearing applications and applications that require long-term reliability.

MATERIALS TODAY BIO (2023)

Article Biochemical Research Methods

A Polarized Raman Spectroscopic Method for Advanced Analyses of the Osteon Lamellar Structure of Human Bone

Giuseppe Pezzotti, Eiji Ishimura, Ryosuke Inai, Wenliang Zhu, Taigi Honma, Nobuhiko Sugano, Wataru Ando, Ugo Pazzaglia, Elia Marin

Summary: Raman spectroscopy is used for quantitative analysis of bone tissue and related materials. This study utilized a high-resolution triple monochromator spectrometer in polarized light configurations to extract details about the crystallographic orientation of apatite and collagen components in human cortical bone. These findings can be crucial in assessing bone structure in both healthy and diseased states.

METHODS AND PROTOCOLS (2022)

Article Biochemical Research Methods

PCA-Assisted Raman Analysis of Osteonecrotic Human Femoral Heads

Eiji Ishimura, Wenliang Zhu, Elia Marin, Taigi Honma, Nobuhiko Sugano, Wataru Ando, Giuseppe Pezzotti

Summary: Osteonecrosis of the femoral head (ONFH) is a common condition in adolescents and young adults, causing hip joint deformity and impairment in standing and walking. Steroid administration and heavy alcohol consumption have been linked to ONFH, but the exact mechanisms are unclear. The current focus is on early diagnosis and treatment strategies.

METHODS AND PROTOCOLS (2022)

Article Chemistry, Physical

Multifunctional continuous solid solution Na0.9Mg0.45Ti3.55O8-Na2Fe2Ti6O16: Preparation, characterization, magnetism, dual absorption, adsorption, and photocatalysis

Qi-Wen Chen, Ze-Qing Guo, Jian-Ping Zhou

Summary: Multifunctional continuous solid solutions NFMTO-x were successfully synthesized via a one-step hydrothermal method by controlling the ratio of Mg and Fe. The NFMTO-x materials exhibited enhanced visible light response, effective adsorption and photocatalytic degradation of organic pollutants, CO2 methanation capability, and easy recyclability due to their magnetic properties. This research provides a significant multifunctional material for water purification.

APPLIED SURFACE SCIENCE (2024)

Review Chemistry, Physical

Critical advances in the field of magnetron sputtered bioactive glass thin-films: An analytical review

George E. Stan, Maziar Montazerian, Adam Shearer, Bryan W. Stuart, Francesco Baino, John C. Mauro, Jose M. F. Ferreira

Summary: Bioactive glasses have the ability to form strong bonds with tissues and release therapeutic ions. However, their biomechanical compatibility limits their use in load-bearing applications. The use of magnetron sputtering technology to fabricate BG coatings shows promise in improving their efficacy and potential for application.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Corrosion mode evaluation of Fe-based glassy alloys with metalloid elements by electrochemical noise (EN)

Zhaoxuan Wang, Zhicheng Yan, Zhigang Qi, Yu Feng, Qi Chen, Ziqi Song, Meng Huang, Peng Jia, Ki Buem Kim, Weimin Wang

Summary: The corrosion behavior of Fe-60 and Fe-83 ribbons in 0.6 M NaCl was studied. Fe-60 exhibited a local corrosion mode and formed a stable passivation film with higher corrosion resistance, while Fe-83 showed a combination of local and global corrosion modes and had lower corrosion resistance. Controlling the precipitation of nanocrystalline phases and increasing the POx content in the passivation film significantly improved the corrosion resistance of Fe-based glassy alloys.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Impacts of Zr content of HfZrOx-Based FeFET memory on resilience towards proton radiation

Hao-Kai Peng, Sheng-Yen Zheng, Wei-Ning Kao, Ting-Chieh Lai, Kai-Sheun Lee, Yung- Hsien Wu

Summary: This study investigates the effects of high energy/fluence proton radiation on the performance of HfZrOx-based FeFETs memory with different Zr content. The results show that the characteristics of FeFETs are influenced by proton radiation, and the extent of the influence depends on the Zr content. FeFETs with 50% Zr content exhibit minimal changes in memory window and demonstrate good endurance and retention performance.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Excellent crystalline silicon surface passivation by transparent conductive Al-doped ZnO/ITO stack

Zongyi Yue, Guangyi Wang, Zengguang Huang, Sihua Zhong

Summary: In this study, AZO and ITO films were successfully tuned as excellent passivation layers for c-Si surfaces, achieving effective minority carrier lifetime and outstanding optical properties through the optimization of annealing temperature and interfacial silicon oxide.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Hydrogen sensing capabilities of highly nanoporous black gold films

Martin Hruska, Jan Kejzlar, Jaroslav Otta, Premysl Fitl, Michal Novotny, Jakub Cizek, Oksana Melikhova, Matej Micusik, Peter Machata, Martin Vrnata

Summary: This paper presents a detailed study on the hydrogen sensing capabilities of highly nanoporous black gold films. The films exhibit fast response and recovery times at low temperatures. Different levels of nanoporosity were prepared and tested to investigate the sensing properties, and it was found that nanoporous black gold is suitable for hydrogen sensing. The sensitivity of the film depends on its nanoporosity.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Abnormal stability of hydrogenic defects and magnetism near the HSrCoO2.5(001) surface

Yupu Wang, Gaofeng Teng, Chun To Yiu, Junyi Zhu

Summary: In the study of BM-SCO and HSCO thin films, it was found that H vacancies tend to prefer sites near the external surface or oxygen vacancy channels (OVCs), while H interstitials prefer sites of oxygen on a layer that contains six-fold coordinated Co. These findings not only enrich the understanding of complex surface phenomena of defect formation but also provide an explanation for the reversibility during phase transformation.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Space variant fiber nanogratings induced by femtosecond laser direct writing

Jiafeng Lu, Linping Teng, Qinxiao Zhai, Chunhua Wang, Matthieu Lancry, Ye Dai, Xianglong Zeng

Summary: In this study, we achieved full control of fiber nanograting orientation by manipulating laser polarization, and tailored space variant fiber nanogratings, which expanded the diversity in fiber nanograting engineering.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Wetting mechanisms in the mass transfer process of CuSi3 droplets on the TC4 and 304SS multi-metal system controlled by the hybrid shielding gas atmosphere

Yibo Liu, Yujie Tao, Yue Liu, Qi Sun, Qinrong Lin, Kexin Kang, Qinghua Zhang, Qingjie Sun

Summary: This study investigates the wettability of the Ti-Cu-Fe multi-metal system, specifically the wetting behaviors of CuSi3 droplets on TC4 and 304SS plates. The results show that the CO2 + Ar gas atmosphere significantly affects interfacial mass transfer, thus influencing the wettability of the systems.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Size-regulated Co-doped hetero-interfaced 3D honeycomb MXene as high performance electromagnetic absorber with anti-corrosion performance

Jimei Liu, Fei Wang, Rong Guo, Yuqi Liu, Mengyu Zhang, Jaka Sunarso, Dong Liu

Summary: This study developed Co/MXene composites with anti-corrosion properties by varying the cobalt content. These composites exhibited remarkable electromagnetic absorption performance and high resistance to corrosion under various corrosive conditions. The study also revealed the mechanism of electron transfer from cobalt to MXene and the electromagnetic dissipation behavior originated from polarization loss alone.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Ultrafine Ru nanoparticles on nitrogen-doped CNT arrays for HER: A CVD-based protocol achieving microstructure design and strong catalyst-support interaction

Moujie Huang, Yongsong Ma, Jingbo Yang, Lingyun Xu, Hangqi Yang, Miao Wang, Xin Ma, Xin Xia, Junhao Yang, Deli Wang, Chuang Peng

Summary: Strong metal-support interactions (SMSIs) are important for enhancing catalytic activities and stability in thermal catalysis. This study demonstrates a method to create SMSIs in electrocatalysis using carbon nanotubes and Ru nanoparticles, resulting in excellent catalytic activity and stability.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Novel biphenylene as cisplatin anticancer drug delivery carrier; insight from theoretical perspective

Ravi Trivedi, Brinti Mondal, Nandini Garg, Brahmananda Chakraborty

Summary: This study explores the potential of biphenylene as a nanocarrier for the delivery of the anticancer drug cisplatin. It is found that biphenylene offers physical stability, rapid release rate, solubility, and bio-compatibilities compared to other nanocarriers. The adsorption of cisplatin on the surface of biphenylene involves charge transfer from cisplatin to biphenylene. The drug is shown to be released at body temperature in an acidic environment. Biphenylene also exhibits excellent cytotoxicity activity and cellular uptake of the drug. Overall, biphenylene shows promise as a potential nanocarrier for cisplatin delivery.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Platform for surface-enhanced Raman scattering in layered quantum materials

Hyun Jeong, Hyeong Chan Suh, Ga Hyun Cho, Rafael Salas-Montiel, Hayoung Ko, Ki Kang Kim, Mun Seok Jeong

Summary: In this study, a potential platform to enhance Raman scattering and increase the number of observable Raman modes in monolayer transition metal dichalcogenides (TMDs) was proposed. The platform consisted of large-scale arrays of gold micropillars (MPs), which were able to enhance the Raman intensity of TMDs and make difficult-to-detect Raman modes observable. The platform showed great industrial advantages and wide applicability due to its low cost, simple process, large controllable area, and short process time.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Cyclotriphosphazene (P3N3) derived FeOx@SPNO-C core-shell nanospheres as peroxymonosulfate activator for degradation via non-radical pathway

Yasir Abbas, Shafqat Ali, Sajjad Ali, Waqar Azeem, Zareen Zuhra, Haoliang Wang, Mohamed Bououdina, Zhenzhong Sun

Summary: In this study, FeOx@SPNO-C core-shell nanospheres as a catalyst for degradation of sulfamethoxazole (SMX) were successfully synthesized. The synergistic interaction between FeOx and SPNO-C, high carbon charge density, and the presence of C = O groups and N/Fe-Nx sites were found to be key factors for the enhanced degradation of SMX.

APPLIED SURFACE SCIENCE (2024)

Article Chemistry, Physical

Hierarchical confinement of Prussian blue nanoparticles via NH2-MIL-88B (Fe): Rational design and electrocatalytic application

Qiaoting Yang, Yuxiao Gong, Yan Qian, Zhou-Qing Xiao, Serge Cosnier, Xue-Ji Zhang, Robert S. Marks, Dan Shan

Summary: This study proposes a hierarchical confinement strategy to design Prussian blue nanoparticles (PB NPs) with satisfactory electrocatalytic ability and stability. The catalytic synthesis of PB NPs is achieved through a hydrothermal process, and the as-prepared PB@NH2MIL exhibits efficient electronic transmission and enhanced electrocatalytic properties.

APPLIED SURFACE SCIENCE (2024)