Neutropenia and leukemia development: genetic risk factors and prognosis

Mutations inSRP54gene cause severe congenital neutropenia as well as Shwachman-Diamond-like syndrome

(2018) Christine Bellanné-Chantelot et al.   BLOOD

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions

(2018) Kinga Winczura et al.   Cell Reports

The Association Between Human Leukocyte Antigens and ITP, TTP, and HIT

(2018) Ali Amin Asnafi et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia

(2017) Paula Savola et al.   HAEMATOLOGICA

EP300-ZNF384 fusion gene product up-regulates GATA3 gene expression and induces hematopoietic stem cell gene expression signature in B-cell precursor acute lymphoblastic leukemia cells

(2017) Akinori Yaguchi et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1–RUNX1T1 leukemia with t(8;12;21)

(2017) Akihiro Abe et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia

(2017) Paula Savola et al.   HAEMATOLOGICA

Role ofCSF3Rmutations in the pathomechanism of congenital neutropenia and secondary acute myeloid leukemia

(2016) Maksim Klimiankou et al.   Annals of the New York Academy of Sciences

Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors

(2016) P. Kaimakis et al.   BLOOD

How I diagnose and treat neutropenia

(2016) David C. Dale   CURRENT OPINION IN HEMATOLOGY

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

(2016) S. Pospisilova et al.   HAEMATOLOGICA

ZNF384 -related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype

(2016) Shinsuke Hirabayashi et al.   HAEMATOLOGICA

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

(2016) S. Pospisilova et al.   HAEMATOLOGICA

ZNF384 -related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype

(2016) Shinsuke Hirabayashi et al.   HAEMATOLOGICA

Metagenomic analysis of bloodstream infections in patients with acute leukemia and therapy-induced neutropenia

(2016) P. Gyarmati et al.   Scientific Reports

From cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formation

(2015) T. Moroy et al.   BLOOD

G-CSF and GM-CSF in Neutropenia

(2015) Hrishikesh M. Mehta et al.   JOURNAL OF IMMUNOLOGY

A novel recurrent EP300–ZNF384 gene fusion in B-cell precursor acute lymphoblastic leukemia

(2015) Y Gocho et al.   LEUKEMIA

Glutathione S-Transferase (GST) Gene Diversity in the Crustacean Calanus finmarchicus – Contributors to Cellular Detoxification

(2015) Vittoria Roncalli et al.   PLoS One

UGT1A1*28 Polymorphism in Chronic Lymphocytic Leukemia: The First Investigation of the Polymorphism in Disease Susceptibility and Its Specific Cytogenetic Abnormalities

(2014) Maria Karakosta et al.   ACTA HAEMATOLOGICA

Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis

(2014) J. Skokowa et al.   BLOOD

Haematopoietic stem cell transplantation for Diamond Blackfan anaemia: a report from the Italian Association of Paediatric Haematology and Oncology Registry

(2014) Franca Fagioli et al.   BRITISH JOURNAL OF HAEMATOLOGY

Gene Polymorphisms and Febrile Neutropenia in Acute Leukemia—No Association with IL-4, CCR-5, IL-1RA, but the MBL-2, ACE, and TLR-4 Are Associated with the Disease in Turkish Patients: A Preliminary Study

(2014) Mustafa Pehlivan et al.   Genetic Testing and Molecular Biomarkers

Collaborating constitutive and somatic genetic events in myeloid malignancies: ASXL1 mutations in patients with germline GATA2 mutations

(2014) J.-B. Micol et al.   HAEMATOLOGICA

Risk factors for febrile neutropenia among patients with cancer receiving chemotherapy: A systematic review

(2013) Gary H. Lyman et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Severe congenital neutropenia and chronic neutrophilic leukemia: an intriguing molecular connection unveiled by oncogenic mutations in CSF3R

(2013) I. P. Touw et al.   HAEMATOLOGICA

Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

(2013) Jonathan Cools-Lartigue et al.   JOURNAL OF CLINICAL INVESTIGATION

The Association of Mutations in RUNX1 and CSF3R with the Development of Leukemia in Severe Congenital Neutropenia: A unique pathway in leukemogenesis

(2013) J Skokowa et al.   KLINISCHE PADIATRIE

Symptom burden and supportive care in patients with acute leukemia

(2013) Camilla Zimmermann et al.   LEUKEMIA RESEARCH

Colony-Stimulating Factors for Febrile Neutropenia during Cancer Therapy

(2013) Charles L. Bennett et al.   NEW ENGLAND JOURNAL OF MEDICINE

The variety of leukemic stem cells in myeloid malignancy

(2013) D H Wiseman et al.   ONCOGENE

Incidence of neoplasia in Diamond Blackfan anemia: a report from the Diamond Blackfan Anemia Registry

(2012) A. Vlachos et al.   BLOOD

Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia

(2012) R. Beekman et al.   BLOOD

High frequency of GATA2 mutations in patients with mild chronic neutropenia evolving to MonoMac syndrome, myelodysplasia, and acute myeloid leukemia

(2012) M. Pasquet et al.   BLOOD

Deletion of chromosome 20 in bone marrow of patients with Shwachman-Diamond syndrome, loss of the EIF6 gene and benign prognosis

(2012) Barbara Pressato et al.   BRITISH JOURNAL OF HAEMATOLOGY

Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases

(2012) Véronique Gelsi-Boyer et al.   Journal of Hematology & Oncology

Sequencing histone-modifying enzymes identifies UTX mutations in acute lymphoblastic leukemia

(2012) B G Mar et al.   LEUKEMIA

MGA, a suppressor ofMYC, is recurrently inactivated in high risk chronic lymphocytic leukemia

(2012) Lorenzo De Paoli et al.   LEUKEMIA & LYMPHOMA

Viral Findings in Adult Hematological Patients with Neutropenia

(2012) Lars Öhrmalm et al.   PLoS One

Genetic Defects in Severe Congenital Neutropenia: Emerging Insights into Life and Death of Human Neutrophil Granulocytes

(2011) Christoph Klein   Annual Review of Immunology

The spectrum of large granular lymphocyte leukemia and Feltyʼs syndrome

(2011) Xin Liu et al.   CURRENT OPINION IN HEMATOLOGY

A novel compound heterozygous HAX1 mutation in a Chinese patient with severe congenital neutropenia and chronic myelomonocytic leukemia transformation but without neurodevelopmental abnormalities

(2011) S.-L. Xue et al.   HAEMATOLOGICA

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

(2011) Laura Pasqualucci et al.   NATURE

Management of febrile neutropenia: ESMO Clinical Practice Guidelines

(2010) J. de Naurois et al.   ANNALS OF ONCOLOGY

Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia

(2010) J Boultwood et al.   LEUKEMIA

The Growth Factor Independence-1 (Gfi1) Is Overexpressed in Chronic Myelogenous Leukemia

(2009) Min Huang et al.   ACTA HAEMATOLOGICA

HAX-1: A multifunctional protein with emerging roles in human disease

(2009) Bengt Fadeel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Prevalence of mutations inELANE,GFI1,HAX1,SBDS,WASandG6PC3in patients with severe congenital neutropenia

(2009) Jun Xia et al.   BRITISH JOURNAL OF HAEMATOLOGY

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

Genetic Insights into Congenital Neutropenia

(2009) Christoph Klein et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Novel genetic etiologies of severe congenital neutropenia

(2009) Kaan Boztug et al.   CURRENT OPINION IN IMMUNOLOGY

Distinct ribosome maturation defects in yeast models of Diamond-Blackfan anemia and Shwachman-Diamond syndrome

(2009) J. B. Moore et al.   HAEMATOLOGICA

Deletions in theVPS13B(COH1) gene as a cause of Cohen syndrome

(2009) I. Balikova et al.   HUMAN MUTATION

The isochromosome i(7)(q10) carrying c.258+2t>c mutation of the SBDS gene does not promote development of myeloid malignancies in patients with Shwachman syndrome

(2009) A Minelli et al.   LEUKEMIA

Lgl2 Executes Its Function as a Tumor Suppressor by Regulating ErbB Signaling in the Zebrafish Epidermis

(2009) Sven Reischauer et al.   PLoS Genetics

Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up

(2008) T. Zenz et al.   BLOOD

Preferential loss of mismatch repair function in refractory and relapsed acute myeloid leukemia: potential contribution to AML progression

(2008) Guogen Mao et al.   CELL RESEARCH

Genetic and molecular diagnosis of severe congenital neutropenia

(2008) Alister C Ward et al.   CURRENT OPINION IN HEMATOLOGY

Expanded mutational spectrum in Cohen syndrome, tissue expression, and transcript variants ofCOH1

(2008) Wenke Seifert et al.   HUMAN MUTATION

Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome

(2008) Karyn M. Austin et al.   JOURNAL OF CLINICAL INVESTIGATION

MDM2 SNP309 Is Associated With Poor Outcome in B-Cell Chronic Lymphocytic Leukemia

(2008) Irina Gryshchenko et al.   JOURNAL OF CLINICAL ONCOLOGY

Transformation of severe congenital neutropenia to early acute lymphoblastic leukemia in a patient with HAX1 mutation and without G-CSF administration or receptor mutation

(2008) S Yetgin et al.   LEUKEMIA