K + and the renin–angiotensin–aldosterone system: new insights into their role in blood pressure control and hypertension treatment

WNK4 kinase is a physiological intracellular chloride sensor

(2019) Jen-Chi Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling

(2019) Kenichi Ishizawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Phosphatase 1 Inhibitor–1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter

(2019) David Penton et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The interplay of renal potassium and sodium handling in blood pressure regulation: critical role of the WNK-SPAK-NCC pathway

(2019) Aihua Wu et al.   JOURNAL OF HUMAN HYPERTENSION

Urinary Potassium Excretion and Progression of CKD

(2019) Hyung Woo Kim et al.   Clinical Journal of the American Society of Nephrology

Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter

(2019) Lei Cheng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Potassium intake modulates the thiazide-sensitive sodium-chloride cotransporter (NCC) activity via the Kir4.1 potassium channel

(2018) Ming-Xiao Wang et al.   KIDNEY INTERNATIONAL

Kir4.1/Kir5.1 Activity Is Essential for Dietary Sodium Intake–Induced Modulation of Na-Cl Cotransporter

(2018) Peng Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Potassium Sensing by Renal Distal Tubules Requires Kir4.1

(2017) Catherina A. Cuevas et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake

(2017) Wakana Shoda et al.   KIDNEY INTERNATIONAL

Speculations on salt and the genesis of arterial hypertension

(2017) Jens Titze et al.   KIDNEY INTERNATIONAL

Potassium Homeostasis: The Knowns, the Unknowns, and the Health Benefits

(2017) Alicia A. McDonough et al.   PHYSIOLOGY

The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation

(2017) Lena L. Rosenbaek et al.   Scientific Reports

Roles and Regulation of Renal K Channels

(2016) Paul A. Welling   Annual Review of Physiology

Potassium depletion stimulates Na-Cl cotransporter via phosphorylation and inactivation of the ubiquitin ligase Kelch-like 3

(2016) Kenichi Ishizawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II HypertensionNovelty and Significance

(2016) Luciana C. Veiras et al.   HYPERTENSION

Does Aldosterone Play a Significant Role for Regulation of Vascular Tone?

(2016) Kristina S. Lyngsø et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Extracellular K+rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl−-dependent and independent mechanisms

(2016) David Penton et al.   JOURNAL OF PHYSIOLOGY-LONDON

Evidence for a critical role of the sympathetic nervous system in hypertension

(2016) Guido Grassi et al.   Journal of the American Society of Hypertension

In Primary Aldosteronism, Mineralocorticoids Influence Exosomal Sodium-Chloride Cotransporter Abundance

(2016) Martin J. Wolley et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation

(2016) Alyssa R. Huebner et al.   MOLECULAR & CELLULAR PROTEOMICS

The mineralocorticoid receptor (MR) regulates ENaC but not NCC in mice with random MR deletion

(2016) Jan Czogalla et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Potassium Modulates Electrolyte Balance and Blood Pressure through Effects on Distal Cell Voltage and Chloride

(2015) Andrew S. Terker et al.   Cell Metabolism

Direct and Indirect Mineralocorticoid Effects Determine Distal Salt Transport

(2015) A. S. Terker et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypertension

(2015) Neil R Poulter et al.   LANCET

Integrated Control of Na Transport along the Nephron

(2014) L. G. Palmer et al.   Clinical Journal of the American Society of Nephrology

Regulation of Potassium Homeostasis

(2014) B. F. Palmer   Clinical Journal of the American Society of Nephrology

Distal Convoluted Tubule

(2014) A. R. Subramanya et al.   Clinical Journal of the American Society of Nephrology

Phosphorylation Decreases Ubiquitylation of the Thiazide-sensitive Cotransporter NCC and Subsequent Clathrin-mediated Endocytosis

(2014) Lena L. Rosenbaek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional coupling of renal K+and Na+handling causes high blood pressure in Na+replete mice

(2014) Helga Vitzthum et al.   JOURNAL OF PHYSIOLOGY-LONDON

Urinary Sodium and Potassium Excretion, Mortality, and Cardiovascular Events

(2014) Martin O'Donnell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of Urinary Sodium and Potassium Excretion with Blood Pressure

(2014) Andrew Mente et al.   NEW ENGLAND JOURNAL OF MEDICINE

KCNJ10 determines the expression of the apical Na-Cl cotransporter (NCC) in the early distal convoluted tubule (DCT1)

(2014) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The absence of intrarenal ACE protects against hypertension

(2013) Romer A. Gonzalez-Villalobos et al.   JOURNAL OF CLINICAL INVESTIGATION

Protein Phosphatase 1 Inhibitor-1 Deficiency Reduces Phosphorylation of Renal NaCl Cotransporter and Causes Arterial Hypotension

(2013) N. Picard et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice

(2013) Mads V. Sorensen et al.   KIDNEY INTERNATIONAL

Regulation of Renal Potassium Secretion: Molecular Mechanisms

(2013) Paul A. Welling   SEMINARS IN NEPHROLOGY

Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses

(2013) N. J. Aburto et al.   BMJ-British Medical Journal

Control of Renin Synthesis and Secretion

(2012) Armin Kurtz   AMERICAN JOURNAL OF HYPERTENSION

Effects of angiotensin II on kinase-mediated sodium and potassium transport in the distal nephron

(2012) Nils van der Lubbe et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Multiphoton Imaging of the Glomerular Permeability of Angiotensinogen

(2012) D. Nakano et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aldosterone does not require angiotensin II to activate NCC through a WNK4–SPAK–dependent pathway

(2012) Nils van der Lubbe et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Aldosterone Paradox: Differential Regulation of Ion Transport in Distal Nephron

(2011) Juan Pablo Arroyo et al.   PHYSIOLOGY

Effects of Potassium Chloride and Potassium Bicarbonate on Endothelial Function, Cardiovascular Risk Factors, and Bone Turnover in Mild Hypertensives

(2010) Feng J. He et al.   HYPERTENSION

Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubule

(2010) Nis B. Pedersen et al.   KIDNEY INTERNATIONAL

Multigene kinase network, kidney transport, and salt in essential hypertension

(2010) Paul A. Welling et al.   KIDNEY INTERNATIONAL

Angiotensin II induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter independent of aldosterone

(2010) Nils van der Lubbe et al.   KIDNEY INTERNATIONAL

The Frequency of Hyperkalemia and Its Significance in Chronic Kidney Disease

(2009) Lisa M. Einhorn et al.   ARCHIVES OF INTERNAL MEDICINE