ATRX Mutations in Pineal Parenchymal Tumors of Intermediate Differentiation

Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma

(2019) Julieann C. Lee et al.   ACTA NEUROPATHOLOGICA

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

(2018) Annekathrin Reinhardt et al.   ACTA NEUROPATHOLOGICA

Subependymal giant cell astrocytoma-like astrocytoma: a neoplasm with a distinct phenotype and frequent neurofibromatosis type-1-association

(2018) Doreen N. Palsgrove et al.   MODERN PATHOLOGY

Gene Fusion in Malignant Glioma: An Emerging Target for Next-Generation Personalized Treatment

(2018) Tao Xu et al.   Translational Oncology

Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma

(2018) Matija Snuderl et al.   Nature Communications

Alternative lengthening of telomeres, ATRX loss and h3-k27m mutations in histologically defined pilocytic astrocytoma with anaplasia

(2018) Fausto J. Rodriguez et al.   BRAIN PATHOLOGY

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

(2017) Ahmet Zehir et al.   NATURE MEDICINE

The Role of ATRX in Glioma Biology

(2017) Pravanya Nandakumar et al.   Frontiers in Oncology

Frequent alternative lengthening of telomeres and ATRX loss in adult NF1-associated diffuse and high-grade astrocytomas

(2016) Fausto J. Rodriguez et al.   ACTA NEUROPATHOLOGICA

Alternative Lengthening of Telomeres in Primary Pancreatic Neuroendocrine Tumors Is Associated with Aggressive Clinical Behavior and Poor Survival

(2016) Joo Young Kim et al.   CLINICAL CANCER RESEARCH

Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine Tumors

(2016) Aatur D. Singhi et al.   CLINICAL CANCER RESEARCH

Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome

(2016) David R. Raleigh et al.   NEURO-ONCOLOGY

Integrated Genomic Characterization of a Pineal Parenchymal Tumor of Intermediate Differentiation

(2016) Yun Jee Kang et al.   World Neurosurgery

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

(2015) Andrey Korshunov et al.   ACTA NEUROPATHOLOGICA

Pineal parenchymal tumours of intermediate differentiation – An evidence-based review of a new pathological entity

(2015) Anthony C Amato-Watkins et al.   BRITISH JOURNAL OF NEUROSURGERY

Telomerase activation by genomic rearrangements in high-risk neuroblastoma

(2015) Martin Peifer et al.   NATURE

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors

(2015) R. L. Flynn et al.   SCIENCE

Germ-line and somatic DICER1 mutations in pineoblastoma

(2014) Leanne de Kock et al.   ACTA NEUROPATHOLOGICA

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Molecular and Morphologic Correlates of the Alternative Lengthening of Telomeres Phenotype in High-Grade Astrocytomas

(2012) Doreen N. Nguyen et al.   BRAIN PATHOLOGY

Expression of O6-methylguanine DNA methyltransferase (MGMT) and immunohistochemical analysis of 12 pineal parenchymal tumors

(2012) Hiromi Kanno et al.   NEUROPATHOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes

(2011) Christopher M. Heaphy et al.   AMERICAN JOURNAL OF PATHOLOGY

Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma

(2011) S. Miller et al.   NEURO-ONCOLOGY

Altered Telomeres in Tumors with ATRX and DAXX Mutations

(2011) C. M. Heaphy et al.   SCIENCE