Epigenetic suppression of liver X receptor β in anterior cingulate cortex by HDAC5 drives CFA-induced chronic inflammatory pain

α-Asarone Alleviated Chronic Constriction Injury–Induced Neuropathic Pain Through Inhibition of Spinal Endoplasmic Reticulum Stress in an Liver X Receptor–Dependent Manner

(2018) Yulong Gui et al.   ANESTHESIA AND ANALGESIA

Coregulation of endoplasmic reticulum stress and oxidative stress in neuropathic pain and disinhibition of the spinal nociceptive circuitry

(2018) Yanhu Ge et al.   PAIN

Liver X Receptors Protect Dorsal Root Ganglia from Obesity-Induced Endoplasmic Reticulum Stress and Mechanical Allodynia

(2018) Chaitanya K. Gavini et al.   Cell Reports

Drugging the pain epigenome

(2017) Ellen Niederberger et al.   Nature Reviews Neurology

Systemic inflammation induces anxiety disorder through CXCL12/CXCR4 pathway

(2016) L. Yang et al.   BRAIN BEHAVIOR AND IMMUNITY

Liver X Receptor β Is Involved in Formalin-Induced Spontaneous Pain

(2016) Xiaohang Bao et al.   MOLECULAR NEUROBIOLOGY

ABCA1/ApoE/HDL Pathway Mediates GW3965-Induced Neurorestoration After Stroke

(2016) Xu Cui et al.   STROKE

The Anterior Cingulate Cortex Is a Critical Hub for Pain-Induced Depression

(2015) Florent Barthas et al.   BIOLOGICAL PSYCHIATRY

Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain

(2015) Bora Inceoglu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic regulation of persistent pain

(2015) Guang Bai et al.   Translational Research

Deactivation of excitatory neurons in the prelimbic cortex via Cdk5 promotes pain sensation and anxiety

(2015) Guo-Qiang Wang et al.   Nature Communications

Xanthine Derivative KMUP-1 Reduces Inflammation and Hyperalgesia in a Bilateral Chronic Constriction Injury Model by Suppressing MAPK and NFκB Activation

(2014) Zen-Kong Dai et al.   MOLECULAR PHARMACEUTICS

Liver X receptor β is essential for the differentiation of radial glial cells to oligodendrocytes in the dorsal cortex

(2014) P Xu et al.   MOLECULAR PSYCHIATRY

Spinal sample showing p-JNK and P38 associated with the pain signaling transduction of glial cell in neuropathic pain

(2014) J Cao et al.   SPINAL CORD

HDAC inhibitors restore C-fibre sensitivity in experimental neuropathic pain model

(2013) Yosuke Matsushita et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cognitive and emotional control of pain and its disruption in chronic pain

(2013) M. Catherine Bushnell et al.   NATURE REVIEWS NEUROSCIENCE

Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors

(2013) Indrek Koppel et al.   NEUROPHARMACOLOGY

Fluoxetine Epigenetically Alters the CaMKIIα Promoter in Nucleus Accumbens to Regulate ΔFosB Binding and Antidepressant Effects

(2013) A J Robison et al.   NEUROPSYCHOPHARMACOLOGY

Activation of Liver X Receptor Induces Macrophage Interleukin-5 Expression

(2012) Yuanli Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis

(2012) Spyridon Theofilopoulos et al.   Nature Chemical Biology

Chronic Pain: Emerging Evidence for the Involvement of Epigenetics

(2012) Franziska Denk et al.   NEURON

A Time-Dependent History of Mood Disorders in a Murine Model of Neuropathic Pain

(2011) Ipek Yalcin et al.   BIOLOGICAL PSYCHIATRY

Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation

(2011) Gaia Cermenati et al.   JOURNAL OF LIPID RESEARCH

Ensemble Encoding of Nociceptive Stimulus Intensity in the Rat Medial and Lateral Pain Systems

(2011) Yang Zhang et al.   Molecular Pain

Activation of liver X receptor reduces global ischemic brain injury by reduction of nuclear factor-κB

(2010) O. Cheng et al.   NEUROSCIENCE

LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

(2010) Ning Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liver X receptor agonist treatment regulates inflammatory response after spinal cord trauma

(2009) Irene Paterniti et al.   JOURNAL OF NEUROCHEMISTRY

Possible protection by notoginsenoside R1 against glutamate neurotoxicity mediated by N-methyl-D-aspartate receptors composed of an NR1/NR2B subunit assembly

(2009) Bin Gu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

MAP kinase and pain

(2008) Ru-Rong Ji et al.   BRAIN RESEARCH REVIEWS

Neuroprotective Potential of Fasudil Mesylate in Brain Ischemia-Reperfusion Injury of Rats

(2008) Qin Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Activation of Liver X Receptors Promotes Neuroprotection and Reduces Brain Inflammation in Experimental Stroke

(2008) Jesús R. Morales et al.   CIRCULATION

Expression of liver X receptor   is essential for formation of superficial cortical layers and migration of later-born neurons

(2008) X. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical excitation and chronic pain

(2008) Min Zhuo   TRENDS IN NEUROSCIENCES