Signaling Cascade through DC-ASGPR Induces Transcriptionally Active CREB for IL-10 Induction and Immune Regulation

CLEC5A is a critical receptor in innate immunity against Listeria infection

(2017) Szu-Ting Chen et al.   Nature Communications

Recognition of Endogenous Nucleic Acids by the Innate Immune System

(2016) Axel Roers et al.   IMMUNITY

Phosphoinositide 3-Kinase δ Regulates Dectin-2 Signaling and the Generation of Th2 and Th17 Immunity

(2016) Min Jung Lee et al.   JOURNAL OF IMMUNOLOGY

Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity

(2016) Susanne Roth et al.   Cell Reports

C-type lectins in immunity: recent developments

(2015) Ivy M Dambuza et al.   CURRENT OPINION IN IMMUNOLOGY

Contribution of MINCLE–SYK Signaling to Activation of Primary Human APCs by Mycobacterial Cord Factor and the Novel Adjuvant TDB

(2015) Jenny Ostrop et al.   JOURNAL OF IMMUNOLOGY

CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 Pathway

(2015) Juin-Hua Huang et al.   PLoS Pathogens

Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity

(2014) Brigitte A. Wevers et al.   Cell Host & Microbe

Clec12a Is an Inhibitory Receptor for Uric Acid Crystals that Regulates Inflammation in Response to Cell Death

(2014) Konstantin Neumann et al.   IMMUNITY

C-Type Lectin-like Receptor LOX-1 Promotes Dendritic Cell-Mediated Class-Switched B Cell Responses

(2014) HyeMee Joo et al.   IMMUNITY

Dendritic Cell Maturation and Survival Are Differentially Regulated by TNFR1 and TNFR2

(2014) Nicola J. Maney et al.   JOURNAL OF IMMUNOLOGY

Tumor-associated Neu5Ac-Tn and Neu5Gc-Tn antigens bind to C-type lectin CLEC10A (CD301, MGL)

(2013) N. Mortezai et al.   GLYCOBIOLOGY

Human T Cell Activation Results in Extracellular Signal-regulated Kinase (ERK)-Calcineurin-dependent Exposure of Tn Antigen on the Cell Surface and Binding of the Macrophage Galactose-type Lectin (MGL)

(2013) Sandra J. van Vliet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MGL signaling augments TLR2-mediated responses for enhanced IL-10 and TNF-α secretion

(2013) Sandra J. van Vliet et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Initiation of GalNAc-type O-glycosylation in the endoplasmic reticulum promotes cancer cell invasiveness

(2013) David J. Gill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beyond pattern recognition: NOD-like receptors in dendritic cells

(2013) Jayendra Kumar Krishnaswamy et al.   TRENDS IN IMMUNOLOGY

Signaling by Myeloid C-Type Lectin Receptors in Immunity and Homeostasis

(2012) David Sancho et al.   Annual Review of Immunology

Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity

(2012) Dominikus Strasser et al.   IMMUNITY

The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase

(2012) Lisa M. Graham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10–producing suppressive CD4+T cells

(2012) Dapeng Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Protein Domain Histochemistry (PDH)

(2012) Peter Nollau et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

DCIR-mediated enhancement of HIV-1 infection requires the ITIM-associated signal transduction pathway

(2011) A. A. Lambert et al.   BLOOD

Phospholipase Cγ2 (PLCγ2) Is Key Component in Dectin-2 Signaling Pathway, Mediating Anti-fungal Innate Immune Responses

(2011) Sara Gorjestani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CLEC-2 activates Syk through dimerization

(2010) C. E. Hughes et al.   BLOOD

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

Tn Glycosylation of the MUC6 Protein Modulates Its Immunogenicity and Promotes the Induction of Th17-biased T Cell Responses

(2010) Teresa Freire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syk-dependent Phosphorylation of CLEC-2

(2010) Sonia Séverin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concomitant Activation and Antigen Uptake via Human Dectin-1 Results in Potent Antigen-Specific CD8+ T Cell Responses

(2010) L. Ni et al.   JOURNAL OF IMMUNOLOGY

The Role of the Transcription Factor CREB in Immune Function

(2010) A. Y. Wen et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

(2010) H. Schoenen et al.   JOURNAL OF IMMUNOLOGY

Role of CREB in modulation of TNFα and IL-10 expression in LPS-stimulated RAW264.7 macrophages

(2010) Dorit Avni et al.   MOLECULAR IMMUNOLOGY

Activation of  -Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine

(2010) S. Manicassamy et al.   SCIENCE

N-glycosylated proteins and distinct lipooligosaccharide glycoforms ofCampylobacter jejunitarget the human C-type lectin receptor MGL

(2009) Nina M. van Sorge et al.   CELLULAR MICROBIOLOGY

Requirement of phospholipase C-γ2 (PLCγ2) for Dectin-1-induced antigen presentation and induction of TH1/TH17 polarization

(2009) Ilaria Tassi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phospholipase Cγ2 Is Critical for Dectin-1-mediated Ca2+Flux and Cytokine Production in Dendritic Cells

(2009) Shengli Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Induction of IL-10 by Zymosan in Dendritic Cells Depends on CREB Activation by the Coactivators CREB-Binding Protein and TORC2 and Autocrine PGE2

(2009) Y. Alvarez et al.   JOURNAL OF IMMUNOLOGY

Identification of Mycobacterial  -Glucan As a Novel Ligand for DC-SIGN: Involvement of Mycobacterial Capsular Polysaccharides in Host Immune Modulation

(2009) J. Geurtsen et al.   JOURNAL OF IMMUNOLOGY

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Dendritic cells and C-type lectin receptors: coupling innate to adaptive immune responses

(2008) Sandra J van Vliet et al.   IMMUNOLOGY AND CELL BIOLOGY

CLEC9A Is a Novel Activation C-type Lectin-like Receptor Expressed on BDCA3+Dendritic Cells and a Subset of Monocytes

(2008) Cristal Huysamen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CLEC5A is critical for dengue-virus-induced lethal disease

(2008) Szu-Ting Chen et al.   NATURE

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY

Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells

(2008) Noriyuki Fujikado et al.   NATURE MEDICINE

Sweet preferences of MGL: carbohydrate specificity and function

(2008) Sandra J. van Vliet et al.   TRENDS IN IMMUNOLOGY