CD137 (4-1BB) Engagement Fine-Tunes Synergistic IL-15– and IL-21–Driven NK Cell Proliferation

IL-21-mediated reversal of NK cell exhaustion facilitates anti-tumour immunity in MHC class I-deficient tumours

(2017) Hyungseok Seo et al.   Nature Communications

Shaping of Natural Killer Cell Antitumor Activity by Ex Vivo Cultivation

(2017) Markus Granzin et al.   Frontiers in Immunology

Requirements for human natural killer cell development informed by primary immunodeficiency

(2016) Emily M. Mace   Current Opinion in Allergy and Clinical Immunology

CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo

(2016) Gengwen Tian et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic Causes of Human NK Cell Deficiency and Their Effect on NK Cell Subsets

(2016) Emily M. Mace et al.   Frontiers in Immunology

Activating and Propagating Polyclonal Gamma Delta T Cells with Broad Specificity for Malignancies

(2014) D. C. Deniger et al.   CLINICAL CANCER RESEARCH

Neuroblastoma Killing Properties of V 2 and V 2-Negative   T Cells Following Expansion by Artificial Antigen-Presenting Cells

(2014) J. P. H. Fisher et al.   CLINICAL CANCER RESEARCH

Human IL-21 and IL-21R deficiencies

(2014) Daniel Kotlarz et al.   CURRENT OPINION IN PEDIATRICS

Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo

(2014) Guangwei Cui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards efficient cancer immunotherapy: advances in developing artificial antigen-presenting cells

(2014) Loek J. Eggermont et al.   TRENDS IN BIOTECHNOLOGY

Inborn errors of the development of human natural killer cells

(2013) Emmanuelle Jouanguy et al.   Current Opinion in Allergy and Clinical Immunology

Human cell-based artificial antigen-presenting cells for cancer immunotherapy

(2013) Marcus O. Butler et al.   IMMUNOLOGICAL REVIEWS

Bispecific T-cells Expressing Polyclonal Repertoire of Endogenous γδ T-cell Receptors and Introduced CD19-specific Chimeric Antigen Receptor

(2013) Drew C Deniger et al.   MOLECULAR THERAPY

Two-Compartment Model of NK Cell Proliferation: Insights from Population Response to IL-15 Stimulation

(2012) Y. M. Zhao et al.   JOURNAL OF IMMUNOLOGY

Natural killer cell distribution and trafficking in human tissues

(2012) Paolo Carrega et al.   Frontiers in Immunology

Reprogramming CD19-Specific T Cells with IL-21 Signaling Can Improve Adoptive Immunotherapy of B-Lineage Malignancies

(2011) H. Singh et al.   CANCER RESEARCH

Augmented Lymphocyte Expansion from Solid Tumors With Engineered Cells for Costimulatory Enhancement

(2011) Kevin M. Friedman et al.   JOURNAL OF IMMUNOTHERAPY

Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytes

(2011) Qunrui Ye et al.   Journal of Translational Medicine

A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development

(2010) E. Eckelhart et al.   BLOOD

A panel of human cell-based artificial APC enables the expansion of long-lived antigen-specific CD4+ T cells restricted by prevalent HLA-DR alleles

(2010) Marcus O. Butler et al.   INTERNATIONAL IMMUNOLOGY

CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells

(2009) T. Baessler et al.   BLOOD

Replicative potential of human natural killer cells

(2009) Hiroyuki Fujisaki et al.   BRITISH JOURNAL OF HAEMATOLOGY

Expansion of Highly Cytotoxic Human Natural Killer Cells for Cancer Cell Therapy

(2009) H. Fujisaki et al.   CANCER RESEARCH

IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation

(2008) Erwan Mortier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Biology of Interleukin-2

(2007) Thomas R. Malek   Annual Review of Immunology