Article
Biochemistry & Molecular Biology
Erkin Kurganov, Kaho Okamoto, Seiji Miyata
Summary: This study investigated the distribution of TRPM8-expressing fibers in the brainstem of mice and found that they were present in various regions including the pons and medulla oblongata. The results also showed possible involvement of TRPM8 in peripheral signaling from the trigeminal nerve. The study provides valuable insights into the function and pathway of TRPM8 in sensory signal transmission.
JOURNAL OF CHEMICAL NEUROANATOMY
(2022)
Article
Neurosciences
Katsuyuki Yamaguchi, Takuya Yazawa
Summary: This study provides morphometric data on the development of the human medullary arcuate nucleus (AN) by examining the brains of preterm and perinatal infants. The results show that AN morphology demonstrates asymmetry and individual variability during the fetal period. The volume and neuronal number of AN increase exponentially with age, while neuronal density decreases exponentially. The AN may undergo neuron death and neuroblasts production after mid-gestation.
NEUROSCIENCE LETTERS
(2024)
Article
Clinical Neurology
Takamichi Kanbayashi, Masahiro Sonoo
Summary: By analyzing lateral medullary infarction cases, this study clarified the detailed course of the corticobulbar tract to the facial nucleus, indicating that the tract descends with the corticospinal tract at least to the middle portion of the medulla, and then ascends to the facial nucleus through the medial and ventral areas of the dorsolateral medulla.
Article
Oncology
Samuel S. McAfee, Silu Zhang, Ping Zou, Heather M. Conklin, Darcy Raches, Giles Robinson, Amar Gajjar, Raja Khan, Paul Klimo, Zoltan Patay, Matthew A. Scoggins
Summary: This study aims to explore the anatomical and neuronal basis of pediatric postoperative cerebellar mutism syndrome (CMS) following medulloblastoma resection. By analyzing patterns of surgical damage and secondary axonal degeneration, the study found that damage to the fastigial nuclei and their associated cerebellar cortices is strongly associated with CMS. Additionally, neuronal dysfunction in the ventral periaqueductal gray area and the left red nucleus were consistent findings in CMS cases.
Article
Clinical Neurology
Tomokatsu Hori, Mikhail Chernov, Yasir A. Alshebib, Yuichi Kubota, Seigo Matsuo, Hideki Shiramizu, Yoshikazu Okada
Summary: This study evaluated the long-term outcomes after resection of brainstem cavernous malformations (BSCMs) and assessed the usefulness of the Lawton grading system. The results showed that experienced neurosurgeons can safely and effectively remove hemorrhagic BSCMs, although there may be postoperative neurological morbidity.
JOURNAL OF NEUROSURGERY
(2023)
Article
Veterinary Sciences
Ajeigbe Sheriff Olawale, Tauheed Abubakar Muazu, James Oliver Nzalak
Summary: The study investigated the histological and functional relationships between the pons and Medulla Oblongata in African Striped Ground Squirrels. It found distinct nuclei in these brain structures that contribute to the squirrels' fine voluntary skills, motor coordination, balance, and visual acuity.
EGYPTIAN JOURNAL OF VETERINARY SCIENCE
(2021)
Article
Clinical Neurology
Marco Sparaco, Maria Carmela Addonizio, Giancarlo Apice, Giuseppina Cafasso, Amedeo D'Alessio, Gabriella Di Iasi, Carmine Franco Muccio
Summary: Lateral medullary syndrome presents with a variety of symptoms depending on the localization of the lesion. Body lateropulsion can occur as a unique manifestation of lateral medullary infarction. Diagnosis of this condition is challenging but should be considered in patients presenting with isolated body lateropulsion without other signs of bulbar involvement. We report a case of a 72-year-old woman who presented with a tendency to fall to the right, which was found to be caused by a small infarct in the right lateral aspect of the medulla.
Article
Neurosciences
Aoi Nakano, Ximeng Yang, Tomoharu Kuboyama, Yuna Inada, Chihiro Tohda
Summary: Diosgenin shows promise in promoting axonal growth and improving motor function in chronic spinal cord injury, making it a potential candidate for therapeutic treatment.
NEUROCHEMICAL JOURNAL
(2021)
Article
Neurosciences
Vivian T. Nguyen, Riri Uchida, Allysa Warling, Lucy J. Sloan, Mark S. Saviano, Bridget Wicinski, Therese Hard, Mads F. Bertelsen, Cheryl D. Stimpson, Kathleen Bitterman, Matthew Schall, Patrick R. Hof, Chet C. Sherwood, Paul R. Manger, Muhammad A. Spocter, Bob Jacobs
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Adhil Bhagwandin, Ulsana Debipersadh, Consolate Kaswera-Kyamakya, Emmanuel Gilissen, Kathleen S. Rockland, Zoltan Molnar, Paul R. Manger
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Jagmeet S. Grewal, Tyler Gloe, Joseph Hegedus, Kathleen Bitterman, Brendon K. Billings, Samson Chengetanai, Sarah Bentil, Victoria X. Wang, Johnny C. Ng, Cheuk Y. Tang, Simon Geletta, Bridget Wicinski, Mads Bertelson, Benjamin C. Tendler, Rogier B. Mars, Geoffrey K. Aguirre, Clare Rusbridge, Patrick R. Hof, Chet C. Sherwood, Paul R. Manger, Muhammad A. Spocter
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Samson Chengetanai, Jonathan D. Tenley, Mads F. Bertelsen, Therese Hard, Adhil Bhagwandin, Mark Haagensen, Cheuk Y. Tang, Victoria X. Wang, Bridget Wicinski, Patrick R. Hof, Paul R. Manger, Muhammad A. Spocter
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Neurosciences
Samson Chengetanai, Adhil Bhagwandin, Mads F. Bertelsen, Therese Hard, Patrick R. Hof, Muhammad A. Spocter, Paul R. Manger
JOURNAL OF COMPARATIVE NEUROLOGY
(2020)
Article
Biology
Muhammad A. Spocter, Chet C. Sherwood, Steven J. Schapiro, William D. Hopkins
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2020)
Article
Multidisciplinary Sciences
Paul R. Manger, Nina Patzke, Muhammad A. Spocter, Adhil Bhagwandin, Karl A. E. Karlsson, Mads F. Bertelsen, Abdulaziz N. Alagaili, Nigel C. Bennett, Osama B. Mohammed, Suzana Herculano-Houzel, Patrick R. Hof, Kjell Fuxe
Summary: By comparing cetacean brains with artiodactyl brains, it was found that cetacean brains show enhanced thermogenetic functionality, possibly related to their aquatic niche.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Jordan Swiegers, Adhil Bhagwandin, Busisiwe C. Maseko, Chet C. Sherwood, Therese Hard, Mads F. Bertelsen, Muhammad A. Spocter, Zoltan Molnar, Paul R. Manger
Summary: In this study, the number, distribution, and neurochemical identities of infracortical white matter neurons were examined in three primate species. The density of WMICs varies across brain regions, with some WMICs containing specific markers like nNOS and calretinin. Squirrel monkeys and crested macaques may serve as valuable animal models for studying WMICs in neurodegenerative and psychiatric disorders in humans.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Anatomy & Morphology
Eniola Risikat Kadir, Aminu Imam, Olayemi Joseph Olajide, Moyosore Saliu Ajao
Summary: High doses of bisphenol-A and melatonin lead to elevated gonadotropins and androgens levels in rats, with disrupted reactive oxygen species in ovarian tissues and altered gene expression in hypothalamus and pituitary glands regulating reproduction. Antioxidant effects of melatonin show promising outcomes against bisphenol-A induced toxicities.
ANATOMY & CELL BIOLOGY
(2021)
Article
Anthropology
Manisha R. Dayal, Brendon K. Billings, Desire Brits, Abdallah Abdallah, Muhammad A. Spocter, Mubarak A. Bidmos
Summary: This study investigates the use of the foramen magnum region in the cranial base for sex estimation in Black South Africans during forensic analyses. The average accuracies obtained through discriminant function analyses ranged from 60-71%, indicating a lower accuracy compared to other skeletal elements. Therefore, caution should be exercised when using the equations provided in this study, and only in the absence of more accurate elements.
ANTHROPOLOGISCHER ANZEIGER
(2022)
Article
Neurosciences
Aminu Imam, Adhil Bhagwandin, Moyosore S. Ajao, Paul R. Manger
Summary: This study provides a detailed analysis of the subpallial telencephalon in tree pangolins, revealing a high degree of similarity with other mammals, indicating evolutionary conservation. The functions associated with subpallial nuclei in other mammals may be directly applicable to tree pangolins, albeit with consideration for specific stimuli related to the life history requirements of the species.
JOURNAL OF COMPARATIVE NEUROLOGY
(2022)
Article
Neurosciences
Aminu Imam, Adhil Bhagwandin, Moyosore S. Ajao, Paul R. Manger
Summary: Despite its short length, the spinal cord of the tree pangolin has a similar anatomical organization to that of other mammals, indicating potential similarities in its functional aspects.
JOURNAL OF COMPARATIVE NEUROLOGY
(2022)
Article
Behavioral Sciences
[Anonymous]
Summary: The 2022 meetings of the J.B. Johnston Club for Evolutionary Neuroscience and Karger Workshop in Evolutionary Neuroscience will be held in San Diego, California, USA, focusing on the concept and forces behind the evolution of the nervous system. The meetings consist of the Karger Workshop and the JBJC meeting, organized by different parties.
BRAIN BEHAVIOR AND EVOLUTION
(2022)
Article
Neurosciences
Demi Oddes, Ayanda Ngwenya, Illke B. Malungo, Anita Burkevica, Therese Hard, Mads F. Bertelsen, Muhammad A. Spocter, D. Michael Scantlebury, Paul R. Manger
Summary: Using orexin-A immunohistochemistry, the distribution, morphology, and nuclear parcellation of orexinergic neurons in the hypothalami of Asiatic lions, African lions, and Southeast African cheetahs were studied. The clustering and distribution of orexinergic neurons in these felids appear to be more complex than in other mammals.
JOURNAL OF COMPARATIVE NEUROLOGY
(2023)
Review
Medicine, General & Internal
Olivia C. Matz, Muhammad Spocter
Summary: Huntington's disease is an autosomal dominant genetic disorder characterized by the degeneration of basal nuclei, causing symptoms such as impaired voluntary movement, cognitive decline, and psychiatric disorders. The accumulation of Huntingtin protein in the striatum leads to the destruction of medium spiny neurons. Currently, there is no cure for Huntington's disease, but there are symptomatic treatments available for chorea and psychiatric conditions.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)