CD161 contributes to prenatal immune suppression of IFN-γ–producing PLZF+ T cells

Memory CD4+ T cells are generated in the human fetal intestine

(2019) Na Li et al.   NATURE IMMUNOLOGY

Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life

(2019) Renée R.C.E. Schreurs et al.   IMMUNITY

The microbiome in preterm birth

(2018) Derrick M. Chu et al.   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

Developmental Origin Governs CD8 + T Cell Fate Decisions during Infection

(2018) Norah L. Smith et al.   CELL

Ontogeny of human mucosal-associated invariant T cells and related T cell subsets

(2018) Ghada Ben Youssef et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-γ and TNF-α

(2018) Michela Frascoli et al.   Science Translational Medicine

Stereotypic Immune System Development in Newborn Children

(2018) Axel Olin et al.   CELL

Preterm birth: Inflammation, fetal injury and treatment strategies

(2017) Ashley K. Boyle et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2

(2017) Naomi McGovern et al.   NATURE

Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery

(2017) Derrick M Chu et al.   NATURE MEDICINE

Onset of human preterm and term birth is related to unique inflammatory transcriptome profiles at the maternal fetal interface

(2017) Radek Bukowski et al.   PeerJ

BCL-2 protects human and mouse Th17 cells from glucocorticoid-induced apoptosis

(2016) J. Banuelos et al.   ALLERGY

Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5

(2016) Michela Frascoli et al.   JOURNAL OF IMMUNOLOGY

LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation

(2016) Alba Llibre et al.   JOURNAL OF IMMUNOLOGY

Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells

(2016) Judith F. Ashouri et al.   JOURNAL OF IMMUNOLOGY

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

(2016) Hui-Fern Koay et al.   NATURE IMMUNOLOGY

Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine

(2016) Maria Nikiforou et al.   Scientific Reports

Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid

(2016) Maria Carmen Collado et al.   Scientific Reports

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Effect of chorioamnionitis on regulatory T cells in moderate/late preterm neonates

(2015) Cesar M. Rueda et al.   HUMAN IMMUNOLOGY

PLZF RegulatesCCR6and Is Critical for the Acquisition and Maintenance of the Th17 Phenotype in Human Cells

(2015) Satya P. Singh et al.   JOURNAL OF IMMUNOLOGY

Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire

(2015) Tanya Dimova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Timely and spatially regulated maturation of B and T cell repertoire during human fetal development

(2015) Erez Rechavi et al.   Science Translational Medicine

Emerging concepts in tissue-resident T cells: lessons from humans

(2015) Joseph J.C. Thome et al.   TRENDS IN IMMUNOLOGY

Chorioamnionitis-induced fetal gut injury is mediated by direct gut exposure of inflammatory mediators or by lung inflammation

(2014) Tim G. A. M. Wolfs et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life

(2014) Joseph J.C. Thome et al.   CELL

Functional Consequences of Interactions between Human NKR-P1A and Its Ligand LLT1 Expressed on Activated Dendritic Cells and B Cells

(2014) D. B. Rosen et al.   JOURNAL OF IMMUNOLOGY

CD39 and CD161 Modulate Th17 Responses in Crohn's Disease

(2014) Aiping Bai et al.   JOURNAL OF IMMUNOLOGY

Invariant natural killer T cells developing in the human fetus accumulate and mature in the small intestine

(2014) L Loh et al.   Mucosal Immunology

Meconium Microbiome Analysis Identifies Bacteria Correlated with Premature Birth

(2014) Alexandria N. Ardissone et al.   PLoS One

CD4 T Cells with Effector Memory Phenotype and Function Develop in the Sterile Environment of the Fetus

(2014) X. Zhang et al.   Science Translational Medicine

Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development

(2014) Edwin Leeansyah et al.   Nature Communications

CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages

(2014) Joannah R. Fergusson et al.   Cell Reports

Characterization of the Fetal Blood Transcriptome and Proteome in Maternal Anti-Fetal Rejection: Evidence of a Distinct and Novel Type of Human Fetal Systemic Inflammatory Response

(2013) JoonHo Lee et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

An expression atlas of human primary cells: inference of gene function from coexpression networks

(2013) Neil A Mabbott et al.   BMC GENOMICS

Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection

(2013) Shokrollah Elahi et al.   NATURE

Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness

(2013) Melanie Wencker et al.   NATURE IMMUNOLOGY

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

Memory T Cell Subsets, Migration Patterns, and Tissue Residence

(2012) Scott N. Mueller et al.   Annual Review of Immunology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Memory CD4+CCR5+ T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1

(2012) M. J. Bunders et al.   BLOOD

Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

(2012) Taheri Sathaliyawala et al.   IMMUNITY

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

(2012) K. A. Casey et al.   JOURNAL OF IMMUNOLOGY

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

Neonatal T-cell maturation and homing receptor responses to Toll-like receptor ligands differ from those of adult naive T cells: relationship to prematurity

(2012) Maricruz Crespo et al.   PEDIATRIC RESEARCH

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Innate signals overcome acquired TCR signaling pathway regulation and govern the fate of human CD161hi CD8 + semi-invariant T cells

(2011) C. J. Turtle et al.   BLOOD

Induction of Lectin-like Transcript 1 (LLT1) Protein Cell Surface Expression by Pathogens and Interferon-γ Contributes to Modulate Immune Responses

(2011) Claire Germain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Naive-Like Population of Human CD1d-Restricted T Cells Expressing Intermediate Levels of Promyelocytic Leukemia Zinc Finger

(2011) M. G. Constantinides et al.   JOURNAL OF IMMUNOLOGY

Preterm Labor and Chorioamnionitis Are Associated with Neonatal T Cell Activation

(2011) Angel A. Luciano et al.   PLoS One

IL-1α Mediated Chorioamnionitis Induces Depletion of FoxP3+ Cells and Ileal Inflammation in the Ovine Fetal Gut

(2011) Tim G. A. M. Wolfs et al.   PLoS One

Altered Development of NKT Cells, γδ T Cells, CD8 T Cells and NK Cells in a PLZF Deficient Patient

(2011) Maggie Eidson et al.   PLoS One

CD161-Expressing Human T Cells

(2011) Joannah R. Fergusson et al.   Frontiers in Immunology

Fetal and Adult Hematopoietic Stem Cells Give Rise to Distinct T Cell Lineages in Humans

(2010) J. E. Mold et al.   SCIENCE

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Generation of PLZF+CD4+T cells via MHC class II–dependent thymocyte–thymocyte interaction is a physiological process in humans

(2009) You Jeong Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Murine neonates develop vigorous in vivo cytotoxic and Th1/Th2 responses upon exposure to low doses of NIMA-like alloantigens

(2008) S. J. Opiela et al.   BLOOD

The Transcription Factor PLZF Directs the Effector Program of the NKT Cell Lineage

(2008) Adam K. Savage et al.   IMMUNITY

The BTB–zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

(2008) Damian Kovalovsky et al.   NATURE IMMUNOLOGY

Maternal Alloantigens Promote the Development of Tolerogenic Fetal Regulatory T Cells in Utero

(2008) J. E. Mold et al.   SCIENCE