Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35

Role of IL-35 in sublingual allergen immunotherapy

(2018) Mohamed H. Shamji et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization

(2018) Chih-Chan Lee et al.   Nature Communications

IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease

(2017) Ivy M. Dambuza et al.   Nature Communications

Commensal Lactobacillus Controls Immune Tolerance during Acute Liver Injury in Mice

(2017) Nobuhiro Nakamoto et al.   Cell Reports

Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells

(2016) Tae Jin Yun et al.   Cell Metabolism

Immunology in the liver — from homeostasis to disease

(2016) Felix Heymann et al.   Nature Reviews Gastroenterology & Hepatology

Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance

(2016) Xavier S. Revelo et al.   Cell Reports

Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members

(2015) Karen O. Dixon et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Autoimmune hepatitis – Update 2015

(2015) Michael P. Manns et al.   JOURNAL OF HEPATOLOGY

Plasmacytoid Dendritic Cells Mediate Anti-inflammatory Responses to a Gut Commensal Molecule via Both Innate and Adaptive Mechanisms

(2014) Suryasarathi Dasgupta et al.   Cell Host & Microbe

Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance

(2014) Tom Luedde et al.   GASTROENTEROLOGY

Roles for Chemokines in Liver Disease

(2014) Fabio Marra et al.   GASTROENTEROLOGY

Plasmacytoid dendritic cell-derived IFN-α promotes murine liver ischemia/reperfusion injury by induction of hepatocyte IRF-1

(2014) Antonino Castellaneta et al.   HEPATOLOGY

Acute autoimmune hepatitis: Many open questions

(2014) Christina Weiler-Normann et al.   JOURNAL OF HEPATOLOGY

Modulation of monocyte/macrophage function: A therapeutic strategy in the treatment of acute liver failure

(2014) Lucia A. Possamai et al.   JOURNAL OF HEPATOLOGY

CD4+CD25+ Foxp3+ Regulatory T Cells Protect against T Cell-Mediated Fulminant Hepatitis in a TGF- -Dependent Manner in Mice

(2014) H.-X. Wei et al.   JOURNAL OF IMMUNOLOGY

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

Interleukin-35 induces regulatory B cells that suppress autoimmune disease

(2014) Ren-Xi Wang et al.   NATURE MEDICINE

IL-27 Production and STAT3-Dependent Upregulation of B7-H1 Mediate Immune Regulatory Functions of Liver Plasmacytoid Dendritic Cells

(2012) B. M. Matta et al.   JOURNAL OF IMMUNOLOGY

IL-12 family cytokines: immunological playmakers

(2012) Dario A A Vignali et al.   NATURE IMMUNOLOGY

CCR9+ Macrophages Are Required for Acute Liver Inflammation in Mouse Models of Hepatitis

(2011) Nobuhiro Nakamoto et al.   GASTROENTEROLOGY

Plasmacytoid Dendritic Cells Are Crucial for the Initiation of Inflammation and T Cell Immunity In Vivo

(2011) Hideaki Takagi et al.   IMMUNITY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo

(2011) Melissa Swiecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tolerogenic plasmacytoid DC

(2010) Benjamin M. Matta et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion

(2010) Zubin M. Bamboat et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-35-mediated induction of a potent regulatory T cell population

(2010) Lauren W Collison et al.   NATURE IMMUNOLOGY

The Liver as a Lymphoid Organ

(2009) Ian Nicholas Crispe   Annual Review of Immunology

Comparison of clinical features and liver histology in acute and chronic autoimmune hepatitis

(2008) Masaki Iwai et al.   HEPATOLOGY RESEARCH

Poor allostimulatory function of liver plasmacytoid DC is associated with pro-apoptotic activity, dependent on regulatory T cells

(2008) Daisuke Tokita et al.   JOURNAL OF HEPATOLOGY

The importance of immune dysfunction in determining outcome in acute liver failure

(2008) Charalambos Gustav Antoniades et al.   JOURNAL OF HEPATOLOGY

CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease

(2008) Husein Hadeiba et al.   NATURE IMMUNOLOGY