Inter-alpha inhibitor proteins attenuate lipopolysaccharide-induced blood–brain barrier disruption and downregulate circulating interleukin 6 in mice

Systemic infusions of anti-interleukin-1β neutralizing antibodies reduce short-term brain injury after cerebral ischemia in the ovine fetus

(2018) Xiaodi Chen et al.   BRAIN BEHAVIOR AND IMMUNITY

Ulinastatin protects brain against cerebral ischemia/reperfusion injury through inhibiting MMP-9 and alleviating loss of ZO-1 and occludin proteins in mice

(2018) Xiao-Fang Li et al.   EXPERIMENTAL NEUROLOGY

Alterations in inter-alpha inhibitor protein expression after hypoxic-ischemic brain injury in neonatal rats

(2018) Clémence Disdier et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Genetics and sex influence peripheral and central innate immune responses and blood-brain barrier integrity

(2018) Michelle A. Erickson et al.   PLoS One

Neutralizing anti-interleukin-1β antibodies reduce ischemia-related interleukin-1β transport across the blood–brain barrier in fetal sheep

(2017) Aparna Patra et al.   NEUROSCIENCE

Effects of age, experience and inter-alpha inhibitor proteins on working memory and neuronal plasticity after neonatal hypoxia-ischemia

(2016) Cynthia M. Gaudet et al.   BEHAVIOURAL BRAIN RESEARCH

Extracellular granzyme K mediates endothelial activation through the cleavage of protease-activated receptor-1

(2016) Mehul Sharma et al.   FEBS Journal

Differential Expression of Inflammatory Cytokines and Stress Genes in Male and Female Mice in Response to a Lipopolysaccharide Challenge

(2016) Ashleigh Everhardt Queen et al.   PLoS One

Inter-  inhibitor protein and its associated glycosaminoglycans protect against histone-induced injury

(2015) H. Chaaban et al.   BLOOD

Anti–IL-6 neutralizing antibody modulates blood-brain barrier function in the ovine fetus

(2015) Jiyong Zhang et al.   FASEB JOURNAL

Interleukin-1β Transfer across the Blood–Brain Barrier in the Ovine Fetus

(2015) Grazyna B Sadowska et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit

(2015) William A. Banks et al.   Journal of Neuroinflammation

Ontogeny of inter-alpha inhibitor proteins in ovine brain and somatic tissues

(2014) Mariya S Spasova et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Effects of inter-alpha inhibitor proteins on neonatal brain injury: Age, task and treatment dependent neurobehavioral outcomes

(2014) Steven W. Threlkeld et al.   EXPERIMENTAL NEUROLOGY

Assessment of Blood-Brain Barrier Function and the Neuroinflammatory Response in the Rat Brain by Using Cerebral Open Flow Microperfusion (cOFM)

(2014) Arijit Ghosh et al.   PLoS One

Downregulation of Blood-Brain Barrier Phenotype by Proinflammatory Cytokines Involves NADPH Oxidase-Dependent ROS Generation: Consequences for Interendothelial Adherens and Tight Junctions

(2014) Keith D. Rochfort et al.   PLoS One

Species-Dependent Blood-Brain Barrier Disruption of Lipopolysaccharide: Amelioration by ColistinIn VitroandIn Vivo

(2013) Liang Jin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ulinastatin attenuates experimental autoimmune encephalomyelitis by enhancing anti-inflammatory responses

(2013) Ming Feng et al.   NEUROCHEMISTRY INTERNATIONAL

Effects of Interleukin-6 on the Expression of Tight Junction Proteins in Isolated Cerebral Microvessels from Yearling and Adult Sheep

(2013) Susan S. Cohen et al.   NEUROIMMUNOMODULATION

Cytokine and chemokine responses in serum and brain after single and repeated injections of lipopolysaccharide: Multiplex quantification with path analysis

(2011) Michelle A. Erickson et al.   BRAIN BEHAVIOR AND IMMUNITY

Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide

(2011) Andrej Kovac et al.   Journal of Neuroinflammation

Neuroprotection by Ulinastatin in Experimental Autoimmune Encephalomyelitis

(2011) Yaqing Shu et al.   NEUROCHEMICAL RESEARCH

Inter-Alpha Inhibitor Protein Level in Neonates Predicts Necrotizing Enterocolitis

(2010) Hala Chaaban et al.   JOURNAL OF PEDIATRICS

Ovine Proinflammatory Cytokines Cross the Murine Blood-Brain Barrier by a Common Saturable Transport Mechanism

(2010) Steven W. Threlkeld et al.   NEUROIMMUNOMODULATION

Inter-Alpha Inhibitor Protein Administration Improves Survival From Neonatal Sepsis in Mice

(2010) Kultar Singh et al.   PEDIATRIC RESEARCH

Inter-α Inhibitor Proteins

(2010) Steven M. Opal et al.   SHOCK

Minimal penetration of lipopolysaccharide across the murine blood–brain barrier

(2009) William A. Banks et al.   BRAIN BEHAVIOR AND IMMUNITY

The Role of Inter-Alpha Inhibitor Proteins in the Diagnosis of Neonatal Sepsis

(2009) Hala Chaaban et al.   JOURNAL OF PEDIATRICS

The blood–brain barrier and immune function and dysfunction

(2009) William A. Banks et al.   NEUROBIOLOGY OF DISEASE

Equivalent Involvement of Inter-α-trypsin Inhibitor Heavy Chain Isoforms in Forming Covalent Complexes with Hyaluronan

(2008) Long Zhu et al.   CONNECTIVE TISSUE RESEARCH