Silencing of RHEB inhibits cell proliferation and promotes apoptosis in colorectal cancer cells via inhibition of the mTOR signaling pathway

POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling

(2018) Yuheng Du et al.   Cell Death & Disease

Physical activity, mediating factors and risk of colon cancer: insights into adiposity and circulating biomarkers from the EPIC cohort

(2017) Krasimira Aleksandrova et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis

(2016) Sandra Fernandes Martins et al.   BMC CANCER

A short interval between bevacizumab and anti-epithelial growth factor receptor therapy interferes with efficacy of subsequent anti-EGFR therapy for refractory colorectal cancer

(2016) Hiroya Taniguchi et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Diet and Colorectal Cancer Risk in Asia - a Systematic Review

(2015) Salman Azeem et al.   Asian Pacific Journal of Cancer Prevention

Colorectal Cancer Screening and Surveillance in the Elderly: Updates and Controversies

(2015) Lukejohn W. Day et al.   Gut and Liver

Rheb signaling and tumorigenesis: mTORC1 and new horizons

(2015) Marisol E. Armijo et al.   INTERNATIONAL JOURNAL OF CANCER

Downregulation of angiogenin inhibits the growth and induces apoptosis in human bladder cancer cells through regulating AKT/mTOR signaling pathway

(2015) Jing Shu et al.   JOURNAL OF MOLECULAR HISTOLOGY

Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy

(2015) Tania Campos et al.   MOLECULAR CARCINOGENESIS

Sex- and gender-specific disparities in colorectal cancer risk

(2015) Sung-Eun Kim   WORLD JOURNAL OF GASTROENTEROLOGY

Rheb phosphorylation is involved in p38-regulated/activated protein kinase-mediated tumor suppression in liver cancer

(2015) MIN ZHENG et al.   Oncology Letters

Point mutations of the mTOR-RHEB pathway in renal cell carcinoma

(2015) Arindam P. Ghosh et al.   Oncotarget

mTOR pathway in colorectal cancer: an update

(2015) Maria Giovanna Francipane et al.   Oncotarget

PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance

(2014) AndrewC Hsieh et al.   ASIAN JOURNAL OF ANDROLOGY

Association between the IFN-γ and IL-1 genetic polymorphisms and colorectal cancer in the Chinese Han population

(2014) BAO-YING FEI et al.   JOURNAL OF GENETICS

Early Detection of Colorectal Cancer Recurrence in Patients Undergoing Surgery with Curative Intent: Current Status and Challenges

(2014) Patrick. E. Young et al.   Journal of Cancer

Bevacizumab reduces tumor targeting of antiepidermal growth factor and anti-insulin-like growth factor 1 receptor antibodies

(2013) Sandra Heskamp et al.   INTERNATIONAL JOURNAL OF CANCER

Mutations in Critical Domains Confer the HumanmTORGene Strong Tumorigenicity

(2013) Avaniyapuram Kannan Murugan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Upregulation of Ras homolog enriched in the brain (Rheb) in lipopolysaccharide-induced neuroinflammation

(2013) Maohong Cao et al.   NEUROCHEMISTRY INTERNATIONAL

Polyisoprenylated Methylated Protein Methyl Esterase Is Both Sensitive to Curcumin and Overexpressed in Colorectal Cancer: Implications for Chemoprevention and Treatment

(2013) Felix Amissah et al.   Biomed Research International

mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

(2012) Ramiro Iglesias-Bartolome et al.   Cell Stem Cell

Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells

(2012) Farhat V.N. Din et al.   GASTROENTEROLOGY

Cellular Entry of Human Papillomavirus Type 16 Involves Activation of the Phosphatidylinositol 3-Kinase/Akt/mTOR Pathway and Inhibition of Autophagy

(2012) Z. Surviladze et al.   JOURNAL OF VIROLOGY

Rheb/mTOR Activation and Regulation in Cancer: Novel Treatment Strategies beyond Rapamycin

(2011) Justin T. Babcock et al.   CURRENT DRUG TARGETS

Signaling circuitries controlling stem cell fate: to be or not to be

(2011) Ramiro Iglesias-Bartolome et al.   CURRENT OPINION IN CELL BIOLOGY

mTOR Signaling and Metabolic Regulation of T Cells: New Potential Therapeutic Targets in Autoimmune Diseases

(2011) Marina Pierdominici et al.   CURRENT PHARMACEUTICAL DESIGN

Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2-null ELT3 cells: A potential treatment for lymphangioleiomyomatosis

(2011) Victoria Makovski et al.   INTERNATIONAL JOURNAL OF CANCER

Surveillance after Curative Resection of Colorectal Cancer

(2009) Adena Scheer et al.   Clinics in Colon and Rectal Surgery

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE