Small GTPase Arf6 regulates diabetes-induced cholesterol accumulation in podocytes

N-terminal mutation of apoA-I and interaction with ABCA1 reveal mechanisms of nascent HDL biogenesis

(2018) Minjing Liu et al.   JOURNAL OF LIPID RESEARCH

Hydroxypropyl-β-cyclodextrin protects from kidney disease in experimental Alport syndrome and focal segmental glomerulosclerosis

(2018) Alla Mitrofanova et al.   KIDNEY INTERNATIONAL

Chronic Kidney Disease

(2017) Angela C Webster et al.   LANCET

Liraglutide and Renal Outcomes in Type 2 Diabetes

(2017) Johannes F.E. Mann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy Protects against Palmitic Acid-Induced Apoptosis in Podocytes in vitro

(2017) Xu-shun Jiang et al.   Scientific Reports

Angiotensin II induces cholesterol accumulation and injury in podocytes

(2017) Yingjie Yang et al.   Scientific Reports

Small GTPase ARF6 Regulates Endocytic Pathway Leading to Degradation of ATP-Binding Cassette Transporter A1Highlights

(2016) Nigora Mukhamedova et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury

(2016) Christopher E. Pedigo et al.   JOURNAL OF CLINICAL INVESTIGATION

Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism

(2016) Catherine Marquer et al.   Nature Communications

Dysregulation of low-density lipoprotein receptor contributes to podocyte injuries in diabetic nephropathy

(2015) Yang Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

(2015) Bei-Bei Chu et al.   CELL

CD36 Mediated Fatty Acid-Induced Podocyte Apoptosis via Oxidative Stress

(2015) Wei Hua et al.   PLoS One

Molecular Mechanisms of Cellular Cholesterol Efflux

(2014) Michael C. Phillips   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid Droplet Accumulation Is Associated with an Increase in Hyperglycemia-Induced Renal Damage

(2013) Eva Kiss et al.   AMERICAN JOURNAL OF PATHOLOGY

Glucagon-Induced Acetylation of Foxa2 Regulates Hepatic Lipid Metabolism

(2013) Ferdinand von Meyenn et al.   Cell Metabolism

Cyclodextrin Protects Podocytes in Diabetic Kidney Disease

(2013) S. Merscher-Gomez et al.   DIABETES

Liver X receptors preserve renal glomerular integrity under normoglycaemia and in diabetes in mice

(2013) Monika Patel et al.   DIABETOLOGIA

Lipid Absorption Defects in Intestine-specific Microsomal Triglyceride Transfer Protein and ATP-binding Cassette Transporter A1-deficient Mice

(2013) Jahangir Iqbal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy

(2013) Michal Herman-Edelstein et al.   JOURNAL OF LIPID RESEARCH

Activation of Liver X Receptor Inhibits Osteopontin and Ameliorates Diabetic Nephropathy

(2012) H. Tachibana et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mutations in the phospholipid remodeling gene SERAC1 impair mitochondrial function and intracellular cholesterol trafficking and cause dystonia and deafness

(2012) Saskia B Wortmann et al.   NATURE GENETICS

Coordination between RAB GTPase and phosphoinositide regulation and functions

(2012) Steve Jean et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages

(2010) Margarita de la Llera-Moya et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Binding of PDZ-RhoGEF to ATP-binding Cassette Transporter A1 (ABCA1) Induces Cholesterol Efflux through RhoA Activation and Prevention of Transporter Degradation

(2010) Keiichiro Okuhira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab8 Regulates ABCA1 Cell Surface Expression and Facilitates Cholesterol Efflux in Primary Human Macrophages

(2009) Matts D. Linder et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation

(2009) Yuya Azuma et al.   GENES TO CELLS

Hyperglycemia and mechanical stress: Targeting the renal podocyte

(2009) Barbara Lewko et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ARF6-Mediated Endosome Recycling Reverses Lipid Accumulation Defects in Niemann-Pick Type C Disease

(2009) Jill Kuglin Schweitzer et al.   PLoS One