Targeted Notch1 inhibition with a Notch1 antibody, OMP‐A2G1, decreases tumor growth in two murine models of prostate cancer in association with differing patterns of DNA damage response gene expression
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Title
Targeted Notch1 inhibition with a Notch1 antibody, OMP‐A2G1, decreases tumor growth in two murine models of prostate cancer in association with differing patterns of DNA damage response gene expression
Authors
Keywords
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Journal
JOURNAL OF CELLULAR BIOCHEMISTRY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-05-17
DOI
10.1002/jcb.28954
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Note: Only part of the references are listed.- Reversal of docetaxel resistance in prostate cancer by Notch signaling inhibition
- (2018) Shi Qiu et al. ANTI-CANCER DRUGS
- Pharmacological inhibition of the Notch pathway enhances the efficacy of androgen deprivation therapy for prostate cancer
- (2018) Jian Cui et al. INTERNATIONAL JOURNAL OF CANCER
- P53 enhances apoptosis induced by doxorubicin only under conditions of severe DNA damage
- (2018) Ru-Wei Lin et al. CELL CYCLE
- Synergistic Activity with NOTCH Inhibition and Androgen Ablation in ERG-Positive Prostate Cancer Cells
- (2017) Ahmed A. Mohamed et al. MOLECULAR CANCER RESEARCH
- TMPRSS2–ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer
- (2017) Ken J Kron et al. NATURE GENETICS
- Notch Pathway Inhibition Using PF-03084014, a -Secretase Inhibitor (GSI), Enhances the Antitumor Effect of Docetaxel in Prostate Cancer
- (2015) D. Cui et al. CLINICAL CANCER RESEARCH
- Notch signaling in the prostate: critical roles during development and in the hallmarks of prostate cancer biology
- (2015) Gang Deng et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- HES6 promotes prostate cancer aggressiveness independently of Notch signalling
- (2015) Filipe L. F. Carvalho et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The TMPRSS2-ERG Gene Fusion Blocks XRCC4-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP Inhibition
- (2015) P. Chatterjee et al. MOLECULAR CANCER THERAPEUTICS
- Notch is a direct negative regulator of the DNA-damage response
- (2015) Jelena Vermezovic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Notch is a direct negative regulator of the DNA-damage response
- (2015) Jelena Vermezovic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Androgen Receptor Promotes the Oncogenic Function of Overexpressed Jagged1 in Prostate Cancer by Enhancing Cyclin B1 Expression via Akt Phosphorylation
- (2014) Yongjiang Yu et al. MOLECULAR CANCER RESEARCH
- Notch signaling in prostate cancer: A moving target
- (2014) Filipe L. F. Carvalho et al. PROSTATE
- Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut
- (2014) Maia Chanrion et al. Nature Communications
- In vitro model systems to study androgen receptor signaling in prostate cancer
- (2013) Natalie Sampson et al. ENDOCRINE-RELATED CANCER
- p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3
- (2012) William H. Chappell et al. CELL CYCLE
- Repression of Androgen Receptor Activity by HEYL, a Third Member of the Hairy/Enhancer-of-split-related Family of Notch Effectors
- (2011) Derek N. Lavery et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
- (2010) Michael C Haffner et al. NATURE GENETICS
- The diverse and contrasting effects of using human prostate cancer cell lines to study androgen receptor roles in prostate cancer
- (2008) Sheng-Qiang Yu et al. ASIAN JOURNAL OF ANDROLOGY
- The Notch pathway in prostate development and cancer
- (2008) Kevin G. Leong et al. DIFFERENTIATION
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