Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5

MAPK modulation of yeast pheromone signaling output and the role of phosphorylation sites in the scaffold protein Ste5

(2019) Matthew J. Winters et al.   MOLECULAR BIOLOGY OF THE CELL

CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5

(2018) María Victoria Repetto et al.   MOLECULAR CELL

Negative Feedback Phosphorylation of Gγ Subunit Ste18 and the Ste5 Scaffold Synergistically Regulates MAPK Activation in Yeast

(2018) Shilpa Choudhury et al.   Cell Reports

Protein kinase C and calcineurin cooperatively mediate cell survival under compressive mechanical stress

(2017) Ranjan Mishra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SCWISh network is essential for survival under mechanical pressure

(2017) Morgan Delarue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterotrimeric G Protein-coupled Receptor Signaling in Yeast Mating Pheromone Response

(2016) Christopher G. Alvaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway

(2016) Jacint G. Sanchez et al.   Cell Reports

Dynamic single cell measurements of kinase activity by synthetic kinase activity relocation sensors

(2015) Eric Durandau et al.   BMC BIOLOGY

A Cellular System for Spatial Signal Decoding in Chemical Gradients

(2015) Björn Hegemann et al.   DEVELOPMENTAL CELL

Anin vivodetection system for transient and low-abundant protein interactions and their kinetics in budding yeast

(2015) Andrea Brezovich et al.   YEAST

RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin

(2015) Zinaida Yudina et al.   Cell Reports

Transmembrane signaling in Saccharomyces cerevisiae as a model for signaling in metazoans: State of the art after 25years

(2014) David Engelberg et al.   CELLULAR SIGNALLING

Phosphoproteomic analyses reveal novel cross-modulation mechanisms between two signaling pathways in yeast

(2014) S. Vaga et al.   Molecular Systems Biology

The RING Domain of the Scaffold Protein Ste5 Adopts a Molten Globular Character with High Thermal and Chemical Stability

(2013) Michal J. Walczak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mate and fuse: how yeast cells do it

(2013) L. Merlini et al.   Open Biology

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy

(2012) Claudine Kraft et al.   EMBO JOURNAL

An integrated image analysis platform to quantify signal transduction in single cells

(2012) Serge Pelet et al.   Integrative Biology

Quantitative and dynamic assay of single cell chemotaxis

(2012) Sung Sik Lee et al.   Integrative Biology

Yeast Protein Phosphatase 2A-Cdc55 Regulates the Transcriptional Response to Hyperosmolarity Stress by Regulating Msn2 and Msn4 Chromatin Recruitment

(2012) W. Reiter et al.   MOLECULAR AND CELLULAR BIOLOGY

M-Track: detecting short-lived protein-protein interactions in vivo

(2012) Aurora Zuzuarregui et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The Proteomics Identifications (PRIDE) database and associated tools: status in 2013

(2012) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Validation of regulated protein phosphorylation events in yeast by quantitative mass spectrometry analysis of purified proteins

(2012) Wolfgang Reiter et al.   PROTEOMICS

Regulation of Cell Wall Biogenesis inSaccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway

(2011) David E. Levin   GENETICS

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Dynamic Control of Yeast MAP Kinase Network by Induced Association and Dissociation between the Ste50 Scaffold and the Opy2 Membrane Anchor

(2010) Katsuyoshi Yamamoto et al.   MOLECULAR CELL

The scaffold protein Ste5 directly controls a switch-like mating decision in yeast

(2010) Mohan K. Malleshaiah et al.   NATURE

Cell signaling: What is the signal and what information does it carry?

(2009) Roger Brent   FEBS LETTERS

Negative feedback that improves information transmission in yeast signalling

(2008) Richard C. Yu et al.   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY