An Inactivation Switch Enables Rhythms in a Neurospora Clock Model

A Robust Model for Circadian Redox Oscillations

(2019) Marta del del Olmo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A symmetric toggle switch explains the onset of random X inactivation in different mammals

(2019) Verena Mutzel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Computing with biological switches and clocks

(2018) Neil Dalchau et al.   Natural Computing

CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch

(2018) Rajesh Narasimamurthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computing with biological switches and clocks

(2018) Neil Dalchau et al.   Natural Computing

Revisiting a skeleton model for the mammalian cell cycle: From bistability to Cdk oscillations and cellular heterogeneity

(2018) Claude Gérard et al.   JOURNAL OF THEORETICAL BIOLOGY

Circadian Proteomic Analysis Uncovers Mechanisms of Post-Transcriptional Regulation in Metabolic Pathways

(2018) Jennifer M. Hurley et al.   Cell Systems

Protein sequestration versus Hill-type repression in circadian clock models

(2016) Jae Kyoung Kim   IET Systems Biology

Feedback, Mass Conservation and Reaction Kinetics Impact the Robustness of Cellular Oscillations

(2016) Katharina Baum et al.   PLoS Computational Biology

Feedback Loops of the Mammalian Circadian Clock Constitute Repressilator

(2016) J. Patrick Pett et al.   PLoS Computational Biology

Mathematical Modeling and Validation of Glucose Compensation of the Neurospora Circadian Clock

(2015) Andrey A. Dovzhenok et al.   BIOPHYSICAL JOURNAL

A Period2 Phosphoswitch Regulates and Temperature Compensates Circadian Period

(2015) Min Zhou et al.   MOLECULAR CELL

Decoupling circadian clock protein turnover from circadian period determination

(2015) L. F. Larrondo et al.   SCIENCE

Circadian systems biology: When time matters

(2015) Luise Fuhr et al.   Computational and Structural Biotechnology Journal

Positive Feedback Promotes Oscillations in Negative Feedback Loops

(2014) Bharath Ananthasubramaniam et al.   PLoS One

Ultrasensitivity part I: Michaelian responses and zero-order ultrasensitivity

(2014) James E. Ferrell et al.   TRENDS IN BIOCHEMICAL SCIENCES

Ultrasensitivity part III: cascades, bistable switches, and oscillators

(2014) James E. Ferrell et al.   TRENDS IN BIOCHEMICAL SCIENCES

The RNA helicase FRH is an ATP-dependent regulator of CK1a in the circadian clock of Neurospora crassa

(2014) Linda Lauinger et al.   Nature Communications

Ras-Mediated Deregulation of the Circadian Clock in Cancer

(2014) Angela Relógio et al.   PLoS Genetics

Neurospora WC-1 Recruits SWI/SNF to Remodel frequency and Initiate a Circadian Cycle

(2014) Bin Wang et al.   PLoS Genetics

Conserved RNA Helicase FRH Acts Nonenzymatically to Support the Intrinsically Disordered Neurospora Clock Protein FRQ

(2013) Jennifer M. Hurley et al.   MOLECULAR CELL

Mechanism for 12 Hr Rhythm Generation by the Circadian Clock

(2013) Pål O. Westermark et al.   Cell Reports

A Circadian Clock-Regulated Toggle Switch Explains AtGRP7 and AtGRP8 Oscillations in Arabidopsis thaliana

(2013) Christoph Schmal et al.   PLoS Computational Biology

Epigenetics meets mathematics: Towards a quantitative understanding of chromatin biology

(2012) Philipp A. Steffen et al.   BIOESSAYS

Metabolic compensation of the Neurospora clock by a glucose-dependent feedback of the circadian repressor CSP1 on the core oscillator

(2012) G. Sancar et al.   GENES & DEVELOPMENT

Switching between oscillations and homeostasis in competing negative and positive feedback motifs

(2012) Weihan Li et al.   JOURNAL OF THEORETICAL BIOLOGY

A mechanism for robust circadian timekeeping via stoichiometric balance

(2012) Jae Kyoung Kim et al.   Molecular Systems Biology

The Interplay of cis-Regulatory Elements Rules Circadian Rhythms in Mouse Liver

(2012) Anja Korenčič et al.   PLoS One

Adaptive Temperature Compensation in Circadian Oscillations

(2012) Paul François et al.   PLoS Computational Biology

Phosphorylations: making the Neurospora crassa circadian clock tick

(2011) A.C.R. Diernfellner et al.   FEBS LETTERS

A New Twist on Clock Protein Phosphorylation: A Conformational Change Leads to Protein Degradation

(2011) Jerome S. Menet et al.   MOLECULAR CELL

Circadian Conformational Change of the Neurospora Clock Protein FREQUENCY Triggered by Clustered Hyperphosphorylation of a Basic Domain

(2011) Christina Querfurth et al.   MOLECULAR CELL

Tuning the Mammalian Circadian Clock: Robust Synergy of Two Loops

(2011) Angela Relógio et al.   PLoS Computational Biology

Dynamic PER repression mechanisms in the Drosophila circadian clock: from on-DNA to off-DNA

(2010) J. S. Menet et al.   GENES & DEVELOPMENT

Fungal Functional Genomics: Tunable Knockout-Knock-in Expression and Tagging Strategies: FIG. 1.

(2009) Luis F. Larrondo et al.   EUKARYOTIC CELL

Multisite protein phosphorylation - from molecular mechanisms to kinetic models

(2009) Carlos Salazar et al.   FEBS Journal

Phosphorylation modulates rapid nucleocytoplasmic shuttling and cytoplasmic accumulation of Neurospora clock protein FRQ on a circadian time scale

(2009) A. C.R. Diernfellner et al.   GENES & DEVELOPMENT

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

Oscillating signaling pathways during embryonic development

(2008) Alexander Aulehla et al.   CURRENT OPINION IN CELL BIOLOGY

Circadian gene expression is resilient to large fluctuations in overall transcription rates

(2008) Charna Dibner et al.   EMBO JOURNAL

Biological switches and clocks

(2008) J. J Tyson et al.   Journal of the Royal Society Interface

Interlocked feedback loops of the circadian clock of Neurospora crassa

(2008) Michael Brunner et al.   MOLECULAR MICROBIOLOGY

Design principles of biochemical oscillators

(2008) Béla Novák et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Simulating Dark Expressions and Interactions of frq and wc-1 in the Neurospora Circadian Clock

(2007) Christian I. Hong et al.   BIOPHYSICAL JOURNAL