Article
Chemistry, Multidisciplinary
Grigorios-Aris Cheimariotis, Maria Riga, Kostas Haris, Konstantinos Toutouzas, Aggelos K. Katsaggelos, Nicos Maglaveras
Summary: The study proposed a novel automatic method for A-line classification, utilizing convolutional neural networks (CNNs) for classification in its core and including arterial wall segmentation and an OCT-specific pre-processing step, as well as a post-processing step based on the majority of classifications. The OCT-specific transformation, based on estimation of the attenuation coefficient in every pixel of the OCT image, was identified as a critical step leading to improved accuracy in plaque type characterization.
APPLIED SCIENCES-BASEL
(2021)
Article
Biochemical Research Methods
Zeinab Hajjarian, Jimmy D. Toussaint, J. Luis Guerrero, Seemantini K. Nadkarni
Summary: This study demonstrated for the first time in living swine the capability of intravascular laser speckle imaging (ILSI) to measure an index of coronary plaque viscoelasticity, showing promising potential in evaluating plaque stability.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Cardiac & Cardiovascular Systems
Xing Luo, Minghao Liu, Shengfang Wang, Yuwu Chen, Xiaoyi Bao, Ying Lv, Shan Zhang, Biyi Xu, Xiuzhu Weng, Xiaoxuan Bai, Ming Zeng, Chen Zhao, Ji Li, Haibo Jia, Bo Yu
Summary: In this study, it was found that docosahexaenoic acid (DHA), salicylic acid, and proline could be used as non-invasive biomarkers to differentiate plaque erosion (PE) and plaque rupture (PR) in ST-segment elevation myocardial infarction (STEMI).
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Biochemical Research Methods
Mansour Abtahi, David LE, Jennifer I. Lim, Xincheng Yao
Summary: This study demonstrates the impact of multimodal fusion on deep learning artery-vein segmentation in optical coherence tomography and OCT angiography, and explores the characteristics used in this segmentation. The performance of multimodal architectures with OCT-OCTA fusion is compared to unimodal architectures with only OCT or OCTA inputs. The results show that both early and late fusion architectures perform competitively. Saliency maps are used to identify the characteristics in OCT and OCTA images for artery-vein segmentation.
BIOMEDICAL OPTICS EXPRESS
(2022)
Article
Biotechnology & Applied Microbiology
Juhwan Lee, Justin N. N. Kim, Lia Gomez-Perez, Yazan Gharaibeh, Issam Motairek, Gabriel T. R. Pereira, Vladislav N. N. Zimin, Luis A. P. Dallan, Ammar Hoori, Sadeer Al-Kindi, Giulio Guagliumi, Hiram G. G. Bezerra, David L. L. Wilson
Summary: This study developed an automated deep learning method for detecting microvessels in intravascular optical coherence tomography (IVOCT) images. The method showed significantly improved microvessel segmentation performance and high classification accuracy. It has important implications for research and potential future treatment planning.
BIOENGINEERING-BASEL
(2022)
Article
Cardiac & Cardiovascular Systems
Wenjie Zuo, Renhua Sun, Xiaoguo Zhang, Yangyang Qu, Zhenjun Ji, Yamin Su, Rui Zhang, Genshan Ma
Summary: Lower quantitative flow ratio (QFR) was found to be associated with vulnerable plaque features defined by intravascular imaging, suggesting that QFR may be a useful tool for ruling out high-risk plaques.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Alexander G. Truesdell, Mirvat A. Alasnag, Prashant Kaul, Syed Tanveer Rab, Robert F. Riley, Michael N. Young, Wayne B. Batchelor, Akiko Maehara, Frederick G. Welt, Ajay J. Kirtane, ACC Interventional Counci
Summary: Coronary angiography has been the standard for diagnosing coronary artery disease and guiding percutaneous coronary intervention (PCI). Intravascular imaging (IVI) technologies are used in conjunction with angiography to better assess plaque morphology and optimize PCI. IVI has utility in preintervention assessment, procedural guidance, and postintervention evaluation. IVI's role in reducing major adverse cardiac events in complex lesions is emerging, and further studies are underway. This paper provides an overview of available IVI technologies, reviews evidence supporting their use in PCI, and advocates for broader utilization.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Ophthalmology
Ko Eun Kim, Seong Joon Ahn, Se Joon Woo, Kyu Hyung Park, Byung Ro Lee, Yeon-Kyung Lee, Yoon-Kyoung Sung
Summary: This study investigated the use of a retinal thickness deviation map for screening hydroxychloroquine retinopathy, showing that this method can enhance diagnostic performance when used in conjunction with traditional screening methods. The map identified different abnormal patterns of retinopathy and had high sensitivity and specificity in diagnosing the condition.
Article
Optics
Yusi Miao, Jun Song, Myeong Jin Ju
Summary: A fast and practical computational cross-calibration method for multiple spectrometers is described, which constructs a signal correlation matrix and can be used for physical alignment or numerical matching of spectra. The performance is comparable to the previously reported optimization approach.
Article
Optics
Yusi Miao, Mahsa Siadati, Jun Song, Da Ma, Yifan Jian, Mirza Faisal Beg, Marinko Sarunic, Myeong Jin Ju
Summary: The article presents a coherent buffer averaging technique for megahertz-rate retinal imaging to improve OCTA contrast, demonstrating a 10-fold increase in phase alignment among buffers. This method provides better OCTA contrast than conventional approaches with a faster acquisition time.
Review
Biochemistry & Molecular Biology
Vlad Constantin Donica, Anisia Iuliana Alexa, Irina Andreea Pavel, Ciprian Danielescu, Manuela Andreea Ciapa, Alexandra Lori Donica, Camelia Margareta Bogdanici
Summary: This paper discusses the increasing prevalence of multiple sclerosis among young people in developing countries and introduces the main biomarkers identified through Optical Coherence Tomography Angiography. It investigates the potential role of this technology in studying changes to the central nervous system.
Article
Cardiac & Cardiovascular Systems
Fuxue Deng, Danni Li, Lei Lei, Qiang Yang, Qing Li, Hongtao Wang, Jie Deng, Qiangsun Zheng, Wei Jiang
Summary: The study found that the Apo B/A1 ratio was higher in ACS patients than CCS patients, and also higher in patients with plaque rupture, erosion, or thrombus. A high Apo B/A1 ratio was associated with a high percentage of vulnerable plaques, and negatively related to fibrous cap thickness in lipid-rich plaques.
CARDIOVASCULAR DIABETOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Emrah Erdogan, Retesh Bajaj, Alexandra Lansky, Anthony Mathur, Andreas Baumbach, Christos Bourantas
Summary: Advancements in stent technology and endovascular devices have improved the safety and effectiveness of second-generation drug-eluting stents. However, in-stent restenosis and stent thrombosis still pose challenges in percutaneous coronary intervention. Recent studies have highlighted the value of intravascular imaging in identifying causes of stent failure and guiding therapy.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Muhua Cao, Linlin Zhao, Xuefeng Ren, Tianyu Wu, Guang Yang, Zhuo Du, Huai Yu, Jiannan Dai, Lulu Li, Yini Wang, Guo Wei, Lijia Ma, Lei Xing, Yingfeng Tu, Shaohong Fang, Jinwei Tian, Haibo Jia, Gary S. Mintz, Bo Yu
Summary: This study investigated nonculprit plaque characteristics in patients with STEMI presenting with PE and PR. Patients with culprit PE have limited pancoronary vulnerability, which may explain better outcomes compared to patients with culprit PR.
JACC-CARDIOVASCULAR IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Reza Fazel, Robert W. Yeh, David J. Cohen, Sunil Rao, Siling Li, Yang Song, Eric A. Secemsky
Summary: The use of intravascular imaging (IVI)-guided percutaneous coronary intervention (PCI) has been increasing among Medicare beneficiaries in the USA. IVI-guided PCI is associated with lower rates of major adverse cardiovascular events and target lesion revascularization compared with standard angiographic guidance.
EUROPEAN HEART JOURNAL
(2023)