Activation of ADAM17 (A Disintegrin and Metalloprotease 17) on Glutamatergic Neurons Selectively Promotes Sympathoexcitation

Deoxycorticosterone acetate-salt hypertension activates placental growth factor in the spleen to couple sympathetic drive and immune system activation

(2018) Marialuisa Perrotta et al.   CARDIOVASCULAR RESEARCH

Glutamatergic neurons of the paraventricular nucleus are critical contributors to the development of neurogenic hypertension

(2018) Tyler Basting et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons

(2017) Yuriko Iwakura et al.   PLoS One

Src Kinases Regulate Glutamatergic Input to Hypothalamic Presympathetic Neurons and Sympathetic Outflow in HypertensionNovelty and Significance

(2016) Xin Qiao et al.   HYPERTENSION

Astrocytes Contribute to Angiotensin II Stimulation of Hypothalamic Neuronal Activity and Sympathetic OutflowNovelty and Significance

(2016) Javier E. Stern et al.   HYPERTENSION

Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors

(2016) Lei Wang et al.   NEUROPHARMACOLOGY

A cholinergic-sympathetic pathway primes immunity in hypertension and mediates brain-to-spleen communication

(2016) Daniela Carnevale et al.   Nature Communications

A Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous Systems

(2016) Jiaxi Xu et al.   Frontiers in Physiology

Angiotensin II type 1 receptor expression in astrocytes is upregulated leading to increased mortality in mice with myocardial infarction-induced heart failure

(2014) Kengo Isegawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TACE/ADAM17 Is Essential for Oligodendrocyte Development and CNS Myelination

(2014) J. Palazuelos et al.   JOURNAL OF NEUROSCIENCE

A mathematical model of salt-sensitive hypertension: the neurogenic hypothesis

(2014) Viktoria A. Averina et al.   JOURNAL OF PHYSIOLOGY-LONDON

Inhibition of TNF-α in hypothalamic paraventricular nucleus attenuates hypertension and cardiac hypertrophy by inhibiting neurohormonal excitation in spontaneously hypertensive rats

(2014) Xin-Ai Song et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Brain Angiotensin-Converting Enzyme Type 2 Shedding Contributes to the Development of Neurogenic Hypertension

(2013) Huijing Xia et al.   CIRCULATION RESEARCH

Neuromodulatory role of angiotensin-(1–7) in the central nervous system

(2013) Mariela M. Gironacci et al.   CLINICAL SCIENCE

TNF-  Downregulates Inhibitory Neurotransmission through Protein Phosphatase 1-Dependent Trafficking of GABAA Receptors

(2013) H. Pribiag et al.   JOURNAL OF NEUROSCIENCE

Cardiovascular effects of angiotensin II and glutamate in the PVN of Dahl salt-sensitive rats

(2012) Alexander Gabor et al.   BRAIN RESEARCH

Renin–Angiotensin System Modulates Neurotransmitters in the Paraventricular Nucleus and Contributes to Angiotensin II-Induced Hypertensive Response

(2012) Jie Qi et al.   Cardiovascular Toxicology

NF-κB in the paraventricular nucleus modulates neurotransmitters and contributes to sympathoexcitation in heart failure

(2011) Yu-Ming Kang et al.   BASIC RESEARCH IN CARDIOLOGY

Angiotensin-Converting Enzyme 2: Central Regulator for Cardiovascular Function

(2010) Huijing Xia et al.   CURRENT HYPERTENSION REPORTS

AT2 receptor signaling and sympathetic regulation

(2010) Lie Gao et al.   CURRENT OPINION IN PHARMACOLOGY

Regulation of central angiotensin type 1 receptors and sympathetic outflow in heart failure

(2009) Irving H. Zucker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin II Type 1 Receptor–Mediated Reduction of Angiotensin-Converting Enzyme 2 Activity in the Brain Impairs Baroreflex Function in Hypertensive Mice

(2009) Huijing Xia et al.   HYPERTENSION

Deficiency of TNFα Converting Enzyme (TACE/ADAM17) Causes a Lean, Hypermetabolic Phenotype in Mice

(2008) Richard W. Gelling et al.   ENDOCRINOLOGY