Journal
HEREDITY
Volume 123, Issue 1, Pages 50-57Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41437-019-0220-4
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Funding
- Medical Research Council University Unit programme grant [MC_UU_00007/2]
- MRC [MC_UU_00007/2] Funding Source: UKRI
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The human genome is not randomly organised, with respect to both the linear organisation of the DNA sequence along chromosomes and to the spatial organisation of chromosomes in the cell nucleus. Here I discuss how these patterns of sequence organisation were first discovered by molecular biologists and how they relate to the patterns revealed decades earlier by cytogeneticists and manifest as chromosome bands.
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