Histone methyltransferase PRDM9 is not essential for meiosis in male mice

Interrogating the Functions of PRDM9 Domains in Meiosis

(2018) Sarah Thibault-Sennett et al.   GENETICS

PRDM9 Methyltransferase Activity Is Essential for Meiotic DNA Double-Strand Break Formation at Its Binding Sites

(2018) Boubou Diagouraga et al.   MOLECULAR CELL

Interrogating the Functions of PRDM9 Domains in Meiosis

(2018) Sarah Thibault-Sennett et al.   GENETICS

Impeding DNA Break Repair Enables Oocyte Quality Control

(2018) Huanyu Qiao et al.   MOLECULAR CELL

PRDM9, a driver of the genetic map

(2018) Corinne Grey et al.   PLoS Genetics

Pharmacological Inhibition of the DNA Damage Checkpoint Prevents Radiation-Induced Oocyte Death

(2017) Vera D. Rinaldi et al.   GENETICS

Repeated losses of PRDM9-directed recombination despite the conservation of PRDM9 across vertebrates

(2017) Zachary Baker et al.   eLife

Pharmacological Inhibition of the DNA Damage Checkpoint Prevents Radiation-Induced Oocyte Death

(2017) Vera D. Rinaldi et al.   GENETICS

The evolutionary turnover of recombination hot spots contributes to speciation in mice

(2016) Fatima Smagulova et al.   GENES & DEVELOPMENT

Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice

(2016) Benjamin Davies et al.   NATURE

Health and population effects of rare gene knockouts in adult humans with related parents

(2016) V. M. Narasimhan et al.   SCIENCE

Hybrid Sterility Locus on Chromosome X Controls Meiotic Recombination Rate in Mouse

(2016) Maria Balcova et al.   PLoS Genetics

Nuclear localization of PRDM9 and its role in meiotic chromatin modifications and homologous synapsis

(2015) Fengyun Sun et al.   CHROMOSOMA

Sex chromosome recombination failure, apoptosis, and fertility in male mice

(2015) Imrul Faisal et al.   CHROMOSOMA

Stable recombination hotspots in birds

(2015) S. Singhal et al.   SCIENCE

PRDM9 Drives Evolutionary Erosion of Hotspots in Mus musculus through Haplotype-Specific Initiation of Meiotic Recombination

(2015) Christopher L. Baker et al.   PLoS Genetics

Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots

(2015) Christopher L. Baker et al.   PLoS Genetics

Histone H2AFX Links Meiotic Chromosome Asynapsis to Prophase I Oocyte Loss in Mammals

(2015) Jeffrey M. Cloutier et al.   PLoS Genetics

PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration

(2014) C. L. Baker et al.   GENOME RESEARCH

Prdm9 Incompatibility Controls Oligospermia and Delayed Fertility but No Selfish Transmission in Mouse Intersubspecific Hybrids

(2014) Petr Flachs et al.   PLoS One

Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway

(2014) E. Bolcun-Filas et al.   SCIENCE

X Chromosome Control of Meiotic Chromosome Synapsis in Mouse Inter-Subspecific Hybrids

(2014) Tanmoy Bhattacharyya et al.   PLoS Genetics

Numerical constraints and feedback control of double-strand breaks in mouse meiosis

(2013) L. Kauppi et al.   GENES & DEVELOPMENT

Mechanistic basis of infertility of mouse intersubspecific hybrids

(2013) T. Bhattacharyya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normalization of ChIP-seq data with control

(2012) Kun Liang et al.   BMC BIOINFORMATICS

Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms

(2012) L. Wojtasz et al.   GENES & DEVELOPMENT

HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes

(2012) Hiroshi Kogo et al.   GENES TO CELLS

Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA

(2012) P. P. Khil et al.   GENOME RESEARCH

ENU mutagenesis in mice identifies candidate genes for hypogonadism

(2012) Jeffrey Weiss et al.   MAMMALIAN GENOME

Genetic recombination is directed away from functional genomic elements in mice

(2012) Kevin Brick et al.   NATURE

Interallelic and Intergenic Incompatibilities of the Prdm9 (Hst1) Gene in Mouse Hybrid Sterility

(2012) Petr Flachs et al.   PLoS Genetics

Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome

(2011) E. Axelsson et al.   GENOME RESEARCH

Prdm9, a Major Determinant of Meiotic Recombination Hotspots, Is Not Functional in Dogs and Their Wild Relatives, Wolves and Coyotes

(2011) Violeta Muñoz-Fuentes et al.   PLoS One

Mutation discovery in mice by whole exome sequencing

(2011) Heather Fairfield et al.   GENOME BIOLOGY

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Prdm9 Controls Activation of Mammalian Recombination Hotspots

(2010) E. D. Parvanov et al.   SCIENCE

Drive Against Hotspot Motifs in Primates Implicates the PRDM9 Gene in Meiotic Recombination

(2010) S. Myers et al.   SCIENCE

PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice

(2010) F. Baudat et al.   SCIENCE

The consequences of asynapsis for mammalian meiosis

(2009) Paul S. Burgoyne et al.   NATURE REVIEWS GENETICS

Mouse consomic strains: Exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies

(2008) S. Gregorova et al.   GENOME RESEARCH

A Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase

(2008) O. Mihola et al.   SCIENCE

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY