E2F1 activates MFN2 expression by binding to the promoter and decreases mitochondrial fission and mitophagy in HeLa cells

Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy

(2017) Anne-Sophie Benischke et al.   Scientific Reports

MiR-195 dependent roles of mitofusin2 in the mitochondrial dysfunction of hippocampal neurons in SAMP8 mice

(2016) Rui Zhang et al.   BRAIN RESEARCH

MicroRNA-761 is upregulated in hepatocellular carcinoma and regulates tumorigenesis by targeting Mitofusin-2

(2016) Xiaohu Zhou et al.   CANCER SCIENCE

Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis

(2016) Rukmini Mukherjee et al.   JOURNAL OF CELL SCIENCE

miR-106a promotes cardiac hypertrophy by targeting mitofusin 2

(2016) Xiaoxiang Guan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Interaction of Mitochondrial Biogenesis and Fission/Fusion Mediated by PGC-1α Regulates Rotenone-Induced Dopaminergic Neurotoxicity

(2016) Kaige Peng et al.   MOLECULAR NEUROBIOLOGY

Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential

(2016) Larry L. Luchsinger et al.   NATURE

Phosphorylation of Ku70 subunit by cell cycle kinases modulates the replication related function of Ku heterodimer

(2016) Soumita Mukherjee et al.   NUCLEIC ACIDS RESEARCH

ChIPBase v2.0: decoding transcriptional regulatory networks of non-coding RNAs and protein-coding genes from ChIP-seq data

(2016) Ke-Ren Zhou et al.   NUCLEIC ACIDS RESEARCH

Transcriptional profiling revealed the anti-proliferative effect of MFN2 deficiency and identified risk factors in lung adenocarcinoma

(2016) Yuqing Lou et al.   TUMOR BIOLOGY

Upregulated miR-17 Regulates Hypoxia-Mediated Human Pulmonary Artery Smooth Muscle Cell Proliferation and Apoptosis by Targeting Mitofusin 2

(2016) Zheng Lu et al.   MEDICAL SCIENCE MONITOR

Regulation of mitochondrial morphology and cell cycle by microRNA-214 targeting Mitofusin2

(2015) Sudha Bucha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma

(2015) Yuqing Lou et al.   MEDICAL ONCOLOGY

miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database

(2015) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

Pro-apoptotic and anti-proliferative effects of mitofusin-2 via PI3K/Akt signaling in breast cancer cells

(2015) LI MA et al.   Oncology Letters

E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1

(2015) Kun Wang et al.   Nature Communications

Overexpression of E2F mRNAs Associated with Gastric Cancer Progression Identified by the Transcription Factor and miRNA Co-Regulatory Network Analysis

(2015) XiaoTian Zhang et al.   PLoS One

Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death

(2014) A. Martorell-Riera et al.   EMBO JOURNAL

Cyclebase 3.0: a multi-organism database on cell-cycle regulation and phenotypes

(2014) Alberto Santos et al.   NUCLEIC ACIDS RESEARCH

A miR-199a/miR-214 Self-Regulatory Network via PSMD10, TP53 and DNMT1 in Testicular Germ Cell Tumor

(2014) Bi-Feng Chen et al.   Scientific Reports

A Combination of Transcriptional and MicroRNA Regulation Improves the Stability of the Relative Concentrations of Target Genes

(2014) Andrea Riba et al.   PLoS Computational Biology

MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2

(2013) Ying Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Grb2 Is Regulated by Foxd3 and Has Roles in Preventing Accumulation and Aggregation of Mutant Huntingtin

(2013) Shounak Baksi et al.   PLoS One

p53 Orchestrates the PGC-1α-Mediated Antioxidant Response Upon Mild Redox and Metabolic Imbalance

(2012) Katia Aquilano et al.   ANTIOXIDANTS & REDOX SIGNALING

E2F-1 lacking the transcriptional activity domain induces autophagy

(2012) Aracely Garcia-Garcia et al.   CANCER BIOLOGY & THERAPY

The promoter activity of human Mfn2 depends on Sp1 in vascular smooth muscle cells

(2012) Eleonora Sorianello et al.   CARDIOVASCULAR RESEARCH

Architecture of the human regulatory network derived from ENCODE data

(2012) Mark B. Gerstein et al.   NATURE

Systems biology of the autophagy-lysosomal pathway

(2011) Anil G. Jegga et al.   Autophagy

PGC-1α, a Key Modulator of p53, Promotes Cell Survival upon Metabolic Stress

(2011) Nirmalya Sen et al.   MOLECULAR CELL

E2F transcription factor-1 regulates oxidative metabolism

(2011) Emilie Blanchet et al.   NATURE CELL BIOLOGY

Towards the global understanding of the autophagy regulatory network

(2010) Marta M. Lipinski   Autophagy

Mitofusin-2 is a novel direct target of p53

(2010) Weilin Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Specific interaction between E2F1 and Sp1 regulates the expression of murine CTP:phosphocholine cytidylyltransferase alpha during the S phase

(2010) Claudia Elena et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions

(2010) Marta M. Lipinski et al.   DEVELOPMENTAL CELL

Regulation of mitofusin-2 expression in skeletal muscleThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process.

(2009) Antonio Zorzano   Applied Physiology Nutrition and Metabolism

Mitochondrial structural and functional dynamics in Huntington's disease

(2009) P. Hemachandra Reddy et al.   BRAIN RESEARCH REVIEWS

Peroxisome proliferator-activated receptor δ regulates mitofusin 2 expression in the heart

(2009) Yuquan Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1

(2009) M. Banerjee et al.   NUCLEIC ACIDS RESEARCH

E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer

(2008) Fabio Petrocca et al.   CANCER CELL

E2F1 regulates autophagy and the transcription of autophagy genes

(2008) S Polager et al.   ONCOGENE

Mitochondrial Fusion Is Increased by the Nuclear Coactivator PGC-1β

(2008) Marc Liesa et al.   PLoS One