Excess glutamate secreted from astrocytes drives upregulation of P-glycoprotein in endothelial cells in amyotrophic lateral sclerosis

Published 2019 View Full Article

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Title
Excess glutamate secreted from astrocytes drives upregulation of P-glycoprotein in endothelial cells in amyotrophic lateral sclerosis
Authors
Keywords
Amyotrophic lateral sclerosis, Blood brain barrier, P-glycoprotein, Pharmacoresistance, Glutamate, Endothelial cells, Riluzole, NMDA receptor
Journal
EXPERIMENTAL NEUROLOGY
Volume 316, Issue -, Pages 27-38
Publisher
Elsevier BV
Online
2019-04-09
DOI
10.1016/j.expneurol.2019.04.002

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