Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2019, Issue 31-32, Pages 5205-5213Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201900608
Keywords
C-H borylation; Metalation; Indolizines; Cross-coupling; Heterocycles
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The C-H borylation of indolizines has not previously been reported. In this communication, we describe our preliminary efforts to apply this chemistry to this scaffold and contrast this approach to directed metalation. Through these methodologies, it was possible obtain a library of substituted indolizines functionalized on both the pyridinic and pyrrole rings.
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