Article
Oncology
Hongyan Li, Min Wang, Yajing Zhang, Fan Hu, Kun Wang, Chenyang Wang, Zairong Gao
Summary: This study investigated the utility of a new PET parameter in predicting progression-free survival and pathologic grade in follicular lymphoma. The results showed that high D-max, high TLG, and elevated serum lactate dehydrogenase were independent predictors of progression-free survival. A scoring system based on these factors effectively stratified patients into different risk categories. Additionally, SUVmax showed some value in distinguishing different grades of lymphoma.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, General & Internal
Woo Hee Choi, Eun Ji Han, Joo Hyun O, Eun Kyoung Choi, Joon-Il Choi, Gyeongsin Park, Byung-Ock Choi, Young-Woo Jeon, Gi-June Min, Seok-Goo Cho, Catholic Univ Lymphoma Grp
Summary: This study investigated the prognostic value of FDG PET/CT in nodal PTCL patients. The study retrospectively reviewed patients who had undergone FDG PET/CT at different stages of treatment and assessed the correlation between FDG PET/CT findings and survival using Cox regression analysis. The results showed that interim and end-of-therapy PET/CT responses were meaningful predictors of outcomes in patients with nodal PTCL.
Article
Oncology
Yi Wen Mo, Zi Zheng Xiao, Yuan Wei, Xin Ling Li, Xu Zhang, Wei Fan
Summary: This study analyzed the clinical accuracy of F-18-FDG PET/CT in assessing treatment response in Burkitt lymphoma at the end of therapy. The results showed that using Deauville 5-point score as a cutoff point significantly related to progression-free survival and overall survival, with DS 5 being a better cutoff point for predicting recurrence or progression.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Yassine Al Tabaa, Clement Bailly, Salim Kanoun
Summary: This article focuses on the role and current applications of 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography in managing lymphoma patients. It discusses potential future directions of innovative metabolic metrics and new radiopharmaceuticals, and highlights the importance of PET in personalized medicine approaches for lymphoma treatment.
Review
Radiology, Nuclear Medicine & Medical Imaging
Robert J. O'Shea, Chris Rookyard, Sam Withey, Gary J. R. Cook, Sophia Tsoka, Vicky Goh
Summary: Radiomic models offer potential for improving the assessment of oesophageal adenocarcinoma through quantitative medical image analysis. However, the selection and generalizability of these models remain challenges. Although radiomic models show promise in predicting and distinguishing clinical features of oesophageal adenocarcinoma, further improvements in sensitivity and generalizability are needed. Future research should prioritize the prospective validation of proposed models to facilitate their clinical translation.
INSIGHTS INTO IMAGING
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Pengcheng Ran, Hui Li, Yongzhen Hu, Miao Chen, Aisheng Dong
Summary: Primary lymphoma of the male breast is rare, but FDG PET/CT can aid in diagnosis by detecting the metabolic activity of the tumor.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaohui Zhang, Lin Chen, Han Jiang, Xuexin He, Liu Feng, Miaoqi Ni, Mindi Ma, Jing Wang, Teng Zhang, Shuang Wu, Rui Zhou, Chentao Jin, Kai Zhang, Wenbin Qian, Zexin Chen, Cheng Zhuo, Hong Zhang, Mei Tian
Summary: The hybrid nomograms combining RS with IPI significantly improved survival prediction in DLBCL. Radiomic analysis on MBV may serve as a potential approach for prognosis assessment in DLBCL.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Rang Wang, Pan Tang, Rong Tian
Summary: This report presents a rare case of primary lymphoma of the sternoclavicular joint, diagnosed through chest CT and biopsy. The key to treatment lies in accurate diagnosis and differential diagnosis.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Multidisciplinary Sciences
Akram Al-Ibraheem, Farah Anwer, Malik E. Juweid, Qaid Ahmed Shagera, Aysar N. Khalaf, Shahed Obeidat, Areen Mansour, Mohammad Ma'koseh, Khalid Halahleh, Imad Jaradat, Nidal Almasri, Asem Mansour
Summary: The study assessed the predictive value of interim FDG-PET/CT in HL patients treated with ABVD chemotherapy. The results showed that iPET was strongly associated with treatment response and prognosis, and could help tailor therapy to individual patients.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Chae Hong Lim, Sang Eun Yoon, Won Seog Kim, Kyung-Han Lee, Seok Jin Kim
Summary: In patients with Asian variant IVLBCL, the distribution and intensity of FDG uptake lesions on PET/CT can be useful for predicting treatment outcomes and survival. The Nodal and EN/DS3-4 groups had worse 5-year event-free survival and overall survival compared to the EN/DS5 group. Treatment-related deaths occurred in the Nodal and EN/DS3-4 groups, highlighting the importance of PET/CT in monitoring IVLBCL patients.
CANCER MANAGEMENT AND RESEARCH
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xuetao Chen, Shuailiang Wang, Yumei Lai, Guochang Wang, Maomao Wei, Xiao Jin, Jin Ding, Yan Zhang, Yunfei Shi, Feng Wang, Hua Zhu, Zhi Yang, Xuejuan Wang
Summary: The study aimed to compare the diagnostic performance of Ga-68-labeled fibroblast activation protein (FAP) inhibitor (FAPI) and F-18-labeled FDG PET/CT in diagnosing lymphomas and investigate the influence of FAP and glycolytic markers on tracer uptake. The results showed that F-18-FDG PET/CT had a higher staging accuracy and detected more lymph node and extranodal lesions than 68Ga-FAPI PET/CT. Ga-68-FAPI PET/CT was inferior in diagnosing lymphomas with low FAP expression, but it could help reveal the molecular profile of lymphomas.
JOURNAL OF NUCLEAR MEDICINE
(2023)
Article
Oncology
Lanping Hu, Nana Luo, Lei Li, Dasheng Qiu, Xiaoyan Hu
Summary: The purpose of this study was to determine the prognostic significance of metabolic parameters in baseline F-18-FDG PET/CT images obtained from patients with AITL. The results showed that TLG is a strong predictor of OS. A new prognostic scoring system for AITL based on clinical indicators and PET/CT metabolic parameters was constructed, which may help to simplify prognosis stratification and personalize treatment.
FRONTIERS IN ONCOLOGY
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Yun Chen, Shan Zheng, Zenan Wu, Yanmin Lin, Weibing Miao
Summary: A 76-year-old man with yellowish discoloration of sclera and skin for 2 months was referred for F-18-FDG PET/CT to characterize a mass in the pancreas. PET/CT images showed intense FDG uptake in the head of the pancreas, with a lymph nodal mass in the hepatic hilar region, consistent with pancreatic malignancy. Histopathologic findings confirmed diffuse large B-cell lymphoma with no evidence of adenocarcinoma.
CLINICAL NUCLEAR MEDICINE
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Wenjie Zhang, Hongbao Sun, Guohua Shen
Summary: A 54-year-old man presented with a growing nodule in the left upper arm, which was diagnosed as diffuse large B-cell lymphoma. After chemotherapy, most involved lesions showed complete remission, except for increased activity at the surgical site. Surgical resection confirmed the diagnosis of foreign body granuloma.
CLINICAL NUCLEAR MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Qixin Wang, Wenxin Tang, Songsong Yang, Yue Chen
Summary: Solitary non-Hodgkin lymphoma of the trachea is extremely rare, presenting symptoms such as cough and dyspnea. Diagnosis typically requires histology and immunohistochemistry confirmation.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ruxandra-Iulia Milos, Sebastian Roehrich, Florian Prayer, Andreas Strassl, Lucian Beer, Benedikt H. Heidinger, Michael Weber, Martin L. Watzenboeck, Daria Kifjak, Dietmar Tamandl, Helmut Prosch
Summary: This study compared the image quality of ultra-high-resolution (UHR) photon-counting detector (PCD) CT image sets of the lungs reconstructed using different kernels and slice thicknesses. The results showed that only the reconstruction using BI64(0.4-mm) yielded improved bronchial division identification and bronchial wall and pulmonary fissure sharpness without a loss in pulmonary vessel sharpness or conspicuity of nodules or other pathologies. Therefore, the findings of this study may guide protocol optimization for UHR PCD CT of the lungs.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Simone Krebs, Jazmin Schwartz, Christian Grommes, Robert J. Young, Heiko Schoder, Marius E. Mayerhoefer
JOURNAL OF NUCLEAR MEDICINE
(2023)
Article
Acoustics
S. F. Nemec, U. Schwarz-Nemec, D. Prayer, M. Weber, D. Bettelheim, G. Kasprian
Summary: This study aimed to investigate human femur development in fetal growth restriction (FGR) by analyzing femur morphometrics and distal epimetaphyseal features on prenatal magnetic resonance imaging (MRI). The results showed significant differences in femur morphometrics between FGR cases and controls, with bone shortening observed in FGR. However, FGR cases and normal controls shared similarly graded distal epimetaphyseal features.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Biology
Lisa Bartha-Doering, Kathrin Kollndorfer, Ernst Schwartz, Florian Ph. S. Fischmeister, Georg Langs, Michael Weber, Sonja Lackner-Schmelz, Patric Kienast, Marlene Stuempflen, Athena Taymourtash, Sophie Mandl, Johanna Alexopoulos, Daniela Prayer, Rainer Seidl, Gregor Kasprian
Summary: The depth asymmetry of the superior temporal sulcus (STS) may serve as a potential biomarker for the maturity and integrity of neural correlates of language. This study explored the prognostic value of STS depth asymmetry in healthy fetuses for later language abilities. The findings suggest that less right fetal STS depth asymmetry is associated with better verbal abilities and increased left language localization during childhood.
COMMUNICATIONS BIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marius E. Mayerhoefer, Markus Raderer, Michael Weber, Wolfgang Lamm, Barbara Kiesewetter, Marcus Hacker, Lukas Nics, Stefan Schmitl, Doris Leithner, Hans-Juergen Wester, Alexander Haug
Summary: The aim of this study was to compare CXCR4 imaging with Ga-68-pentixafor PET to MRI for treatment response assessment in patients with mantle cell lymphoma (MCL). The results indicated that Ga-68-pentixafor PET is superior to MRI for assessing complete remission status in MCL patients, especially at the end of treatment.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Doris Leithner, Rachel B. Nevin, Peter Gibbs, Michael Weber, Ricardo Otazo, H. Alberto Vargas, Marius E. Mayerhoefer
Summary: The study aimed to determine whether ComBat harmonization improves tissue classification in heterogeneous MRI datasets and compared the performances of 2 ComBat variants. A total of 100 patients who underwent T1-weighted 3D gradient echo Dixon MRI were included. Radiomic features were extracted and tissue classification was performed without harmonization, after ComBat harmonization with empirical Bayes estimation (ComBat-B), and after ComBat harmonization without empirical Bayes estimation (ComBat-NB). The results showed that ComBat harmonization can improve the classification accuracy of multicenter MRI radiomics studies with nonbinary tasks.
INVESTIGATIVE RADIOLOGY
(2023)
Article
Endocrinology & Metabolism
Katharina Kerschan-Schindl, Peter Dovjak, Maria Butylina, Anna Rainer, Bernhard Mayr, Veronika Roeggla, Helmuth Haslacher, Michael Weber, Galateja Jordakieva, Peter Pietschmann
Summary: In COVID-19 patients with moderately severe disease, bone metabolism is altered but remains coupled. Therefore, it is important to evaluate bone turnover markers and fracture risk in these patients during the post-infection period.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Medicine, General & Internal
Elizabeth Katherine Anna Triumbari, Roberto Gatta, Elena Maiolo, Marco De Summa, Luca Boldrini, Marius E. Mayerhoefer, Stefan Hohaus, Lorenzo Nardo, David Morland, Salvatore Annunziata
Summary: This study explores the predictive role of baseline F-18-FDG PET/CT radiomics in patients with classical Hodgkin's lymphoma (cHL). Two target lesions were selected for radiomic feature extraction and logistic regression analysis was conducted to build bivariate models for Deauville score (DS) and 24-month progression-free survival (PFS) prediction. The best models showed promising results and suggest that FDG-PET/CT radiomic features from specific lesions may provide valuable information for treatment response and prognosis in cHL patients.
Article
Neurosciences
Sophie Mandl, Patric Kienast, Kathrin Kollndorfer, Gregor Kasprian, Michael Weber, Rainer Seidl, Lisa Bartha-Doering
Summary: This study found that the size of the corpus callosum (CC) is related to theory of mind (ToM) abilities in healthy children. Specifically, larger mid-anterior and central subsections of the CC are significantly correlated with better ToM abilities. Additionally, age and sex have an impact on the relationship between the CC and ToM.
Article
Endocrinology & Metabolism
Katharina Thom, Janina Maria Patsch, Florentina Haufler, Christiane Pees, Sulaima Albinni, Michael Weber, Christoph Male, Adalbert Raimann
Summary: Childhood and adolescence are critical periods for bone mineral acquisition. Children on anticoagulation (AC) may have an increased risk for reduced bone mineral density (BMD). Risk factors for impaired bone accumulation include chronic diseases, immobility, and medication. Vitamin K (VK) deficiency, reflected by low levels of undercarboxylated osteocalcin, has been identified as a predictor of osteoporosis and fractures. Data on bone health in children on AC are limited.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Christian Wassipaul, Karin Janata-Schwatczek, Hans Domanovits, Dietmar Tamandl, Helmut Prosch, Martina Scharitzer, Stephan Polanec, Ruediger E. Schernthaner, Thomas Mang, Ulrika Asenbaum, Paul Apfaltrer, Filippo Cacioppo, Nikola Schuetz, Michael Weber, Peter Homolka, Wolfgang Birkfellner, Christian Herold, Helmut Ringl
Summary: This study compared the detection rates and clinical relevance of ultra-low-dose CT (ULDCT) and chest X-ray (CXR) in non-traumatic emergency department patients. The results showed that ULDCT had more than twice the detection rate for main diagnoses compared to CXR, and ULDCT also had higher detection rates for additional imaging modalities.
Article
Geriatrics & Gerontology
Peter Dovjak, Bernhard Iglseder, Anna Rainer, Gregor Dovjak, Michael Weber, Peter Pietschmann
Summary: The present study aimed to investigate the accuracy of pulse-echo ultrasound measurement of the lower leg for the detection of osteoporosis in older patients and evaluate the effect of a proposed diagnostic algorithm. It was found that the sensitivity of the ultrasound device was 94.4% and the specificity was 59% compared to dual-energy X-ray absorptiometry. Based on the proposed algorithm, specific treatment for osteoporosis could be determined in 90.9% of the patients.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nathania Bonanno, Dania Cioni, Damiano Caruso, Clemens C. Cyran, Julien Dinkel, Laure Fournier, Sofia Gourtsoyianni, Ralf-Thorsten Hoffmann, Andrea Laghi, Laura Martincich, Marius E. Mayerhoefer, Giulia A. Zamboni, Evis Sala, Heinz-Peter Schlemmer, Emanuele Neri, Melvin D'Anastasi
Summary: A survey of radiologists' opinions on the shift from in-person oncologic multidisciplinary team meetings (MDTMs) to online MDTMs showed that the majority viewed online meetings as a viable alternative, enabling high-quality care and coordination between specialties. The clinical standard of online MDTMs was reported to be comparable to in-person meetings, with no hindrance to interdisciplinary discussion and review of imaging data. Most participants favored a combination of online and in-person meetings.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sarah Poetter-Lang, Gregor O. Dovjak, Alina Messner, Raphael Ambros, Stephan H. Polanec, Pascal A. T. Baltzer, Antonia Kristic, Alexander Herold, Jacqueline C. Hodge, Michael Weber, Nina Bastati, Ahmed Ba-Ssalamah
Summary: Saline-diluted gadoxetic acid reduces arterial-phase artifacts without significant effects on signal intensity and focal lesion conspicuity.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sebastian Roehrich, Benedikt H. Heidinger, Florian Prayer, Michael Weber, Markus Krenn, Rui Zhang, Julie Sufana, Jakob Scheithe, Incifer Kanbur, Aida Korajac, Nina Poetsch, Marcus Raudner, Ali Al-Mukhtar, Barbara J. Fueger, Ruxandra-Iulia Milos, Martina Scharitzer, Georg Langs, Helmut Prosch
Summary: The study evaluated the impact of CBIRS on interpreting chest CT scans in patients with diffuse parenchymal lung disease, showing that CBIRS reduced reading time, increased radiologists' information search frequency, and trended towards improving overall diagnostic accuracy when available.
EUROPEAN RADIOLOGY
(2023)