Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors

Published 2019 View Full Article

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Title
Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors
Authors
Keywords
STAT3, Benzo[, b, ]thiophene 1, 1-Dioxide, N, , , N, -Diethyl-7-aminocoumarin fluorophore, Ser727 phosphorylation, Mitochondrial apoptosis pathway, Antitumor activity
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 174, Issue -, Pages 236-251
Publisher
Elsevier BV
Online
2019-04-16
DOI
10.1016/j.ejmech.2019.04.024

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