Synthesis and biological evaluation of pyrazolo[3,4-b]pyridine-3-yl pyrimidine derivatives as sGC stimulators for the treatment of pulmonary hypertension

Title
Synthesis and biological evaluation of pyrazolo[3,4-b]pyridine-3-yl pyrimidine derivatives as sGC stimulators for the treatment of pulmonary hypertension
Authors
Keywords
Riociguat, pyrazolo[3,4-b]pyridine-3-yl pyrimidine derivatives, sGC stimulators, Pulmonary hypertension
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 173, Issue -, Pages 107-116
Publisher
Elsevier BV
Online
2019-04-10
DOI
10.1016/j.ejmech.2019.04.014

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