Article
Engineering, Environmental
Swati Verma, Ki-Hyun Kim, Navneet Kumar, Satya Sundar Bhattacharya, Mu Naushad, Raj Kumar Dutta
Summary: In this study, ammonia-functionalized graphene oxide (NH(3)GO) sheets were synthesized via solvothermal method for the adsorptive removal of organic pollutants in water. The NH(3)GO sheets exhibited high adsorption capacity and partition coefficient for different types of organic pollutants. Thermodynamic analysis revealed the endothermic and spontaneous nature of the adsorption process.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Physical
P. Sirajudheen, Perumal Karthikeyan, Krishnapillai Ramkumar, P. Nisheetha, Sankaran Meenakshi
Summary: A magnetically retrievable adsorbent was successfully fabricated with high removal efficiency towards dye molecules.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Tariq A. Altalhi, Mohamed M. Ibrahim, Gaber A. M. Mersal, M. H. H. Mahmoud, Tushar Kumeria, Mohamed G. El-Desouky, Ashraf A. El-Bindary, Mohamed A. El-Bindary
Summary: In this study, mango seeds activated carbon (MSAC) nanoparticles were prepared with high biocompatibility for potential use as drug carriers. The experimental results showed that the nanocomposite significantly enhanced the adsorption performance of the anti-cancer drug DOX, indicating its potential in drug delivery applications.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Environmental Sciences
Ping Jiang, Guanzhong Zhou, Cuihong Li, Yanfei Yu, Lin Zhou, Haibo Kang
Summary: This study investigated the use of gypsum as an adsorbent for the removal of graphene oxide (GO) under different conditions. The results showed that the optimal conditions for GO removal were a solution pH of 8.0, gypsum dosage of 60 mg, initial GO concentration of 80 mg/L, and temperature of 303 K. The adsorption of GO by gypsum followed the Langmuir isotherm model, and it was found to be a spontaneous exothermic process. Characterization of the gypsum-graphene oxide composites provided insights into the mineral interactions and their impact on contaminant removal.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Oluwayinka M. Adedeji, Kauser Jahan
Summary: In this study, the adsorption of oxidizable reducing pollutants from aqueous co-product (ACP) onto granular and powdered activated carbon (GAC and PAC) was investigated. The results showed that PAC exhibited higher adsorptive capacity than GAC for COD, boron, copper, and phenol. The adsorption isotherms followed different models for PAC and GAC, and the Free Energy Change (Delta G0) indicated spontaneous reactions for copper and phenol adsorption. This study provides important information for the design of adsorption systems for ACP treatment.
Article
Energy & Fuels
Oluwatobi Samuel Agboola, Olugbenga Solomon Bello
Summary: Activated carbon from banana stalk was prepared and investigated for its potential in removing ciprofloxacin from water. The activated carbon showed well-developed pores and specific functional groups that enhanced the uptake of ciprofloxacin. The Langmuir isotherm best described the adsorption data, and the activated carbon was found to be an efficient and cost-effective adsorbent for ciprofloxacin removal.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Environmental Sciences
Tasrin Shahnaz, V. Vishnu Priyan, Sivakumar Pandian, Selvaraju Narayanasamy
Summary: The study focused on the adsorption of antibiotic Ciprofloxacin (CPXO) and anti-inflammatory agent Diclofenac (DCF) on Grass nanocellulose (GNC) extracted from Cyprus rotundas grass. Various experimental measures were optimized to study the adsorption process, and the maximum adsorption capacity of GNC for CPXO and DCF were determined. Phytotoxicity studies on plants and acute fish toxicity analysis on zebra fish were conducted to evaluate the effect of treated effluent on biological organisms.
ENVIRONMENTAL POLLUTION
(2021)
Article
Engineering, Environmental
Laishram Saya, W. Rameshwor Singh, Sunita Hooda
Summary: Given the large amount of harmful pharmaceuticals being released into the water stream, it is crucial to eradicate or reduce these chemicals to a minimum permissible limit. This study reports the fabrication of a magnetic guar gum graphene oxide nano-composite (mGG/GO NC) for the adsorption of ciprofloxacin from wastewater. Various techniques were used to characterize the guar gum and the nanocomposite, and it was found that the adsorption process followed the pseudo second order model and Langmuir isotherm model. The nanocomposite exhibited high adsorption capacity and recyclability, potentially due to a synergistic effect of multiple interactions in the adsorption mechanism.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Environmental Sciences
Yi Wang, Xuelin Chen, Jingfan Yan, Tianyu Wang, Xiaomin Xie, Sen Yang
Summary: Ce3+-enriched Ce-BC exhibited high adsorption capacity for As(V), with adsorption fitting the Langmuir model and described by the pseudo-second-order kinetics model. Decreasing Ce3+ concentration significantly reduced As(V) adsorption, indicating a strong affinity between As(V) and Ce3+.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Chemistry, Analytical
Hany M. Youssef, Wisam O. Toamah
Summary: In this study, nanoparticles of calcium oxide were synthesized using the sol-gel technique and introduced as a highly efficient adsorbent for removing nickel ions from aqueous solutions. The adsorbent was characterized and evaluated through various analyses, demonstrating its potential for efficient adsorption and regeneration. The results showed that CaO-NPs have rapid and efficient removal capabilities and good applicability in environmental cleaning and wastewater treatment.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Gamil A. A. S. AlHazmi, Khlood G. AbouMelha, Mohamed A. El-Desouky, Ashraf El-Bindary
Summary: Zirconium metal organic framework (Zr-MOF) was synthesized by hydrothermal method, and various spectroscopic methods were used for sample characterization. The adsorption of doxorubicin (DOX) onto Zr-MOF was studied. The effects of DOX concentration, contact time, solution pH, and temperature were investigated. The surface properties of Zr-MOF were determined by scanning electron microscopy (SEM). The adsorption efficiency of Zr-MOF for DOX was found to be higher at pH 6. The equilibrium isotherms and kinetic data were described using different adsorption models. The docking interactions between DOX and lung cancer and liver cancer receptors were evaluated.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Multidisciplinary
P. E. Dim, L. S. Mustapha, M. Termtanun, J. O. Okafor
Summary: The study focused on using modified clay as adsorbents to remove heavy metals from industrial effluents, showing promising results in terms of adsorption efficiency and cost-effectiveness.
ARABIAN JOURNAL OF CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Mohamed E. Mahmoud, Shaimaa R. Saad, Abdel Moneim El-Ghanam, Rabah Hanem A. Mohamed Department
Summary: The study fabricated novel magnetic adsorbents Fe3O4-MoO3 and Fe3O4-MoO3-AC, characterized their properties through various techniques, optimized the adsorption performance, found that the addition of activated carbon enhanced the removal of ciprofloxacin molecule, and investigated different adsorption isotherm models and kinetics models to better understand the removal process of antibiotics from aquatic systems.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Chemistry, Physical
Yalcin Altunkaynak, Mutlu Canpolat, Mehmet Aslan
Summary: Due to industrial activity, heavy metal contamination is present in water, air, and soil around the world, leading to serious environmental issues. In this investigation, natural kaolin (NK) clay was used as an effective adsorbent to remove Pb2+ from solution. The adsorption capacity and efficiency of NK were influenced by factors such as contact duration, dosage, temperature, and pH. It was found that NK had a maximum desorption efficiency of 93.07% and showed potential as an eco-friendly adsorbent for heavy metal removal.
Article
Chemistry, Physical
Julia D. Bronzato, Juliana D. Bronzato, Adrianne M. M. Brito, Jefferson Bettini, Maicon R. Z. Passini, Brenda P. F. A. Gomes, Iseli L. Nantes
Summary: A study found that magnetic Co3O4 quantum dots synthesized using biomolecules from tomato seed extract can efficiently degrade the emergent pollutant Ciprofloxacin under UV irradiation, reducing the risk of bacteria developing resistance.
APPLIED SURFACE SCIENCE
(2023)
Review
Engineering, Biomedical
Faisal Raza, Lauren Evans, Mahzad Motallebi, Hajra Zafar, Miguel Pereira-Silva, Kalsoom Saleem, Diana Peixoto, Abbas Rahdar, Esmaeel Sharifi, Francisco Veiga, Clare Hoskins, Ana Claudia Paiva-Santos
Summary: Pancreatic cancer is a challenging and often considered incurable disease. Liposomes have shown promise as future drug delivery systems for pancreatic cancer treatment due to their versatility, ease of fabrication, and modification. This review explores the various mechanisms of liposomes in treating pancreatic cancer, including chemotherapy, targeted therapy, mRNA therapy, immunotherapy, and photothermal therapy. Although multifunctional liposomal formulations have shown pre-clinical success, none have been clinically approved for pancreatic cancer. This review sheds light on the progress made so far and provides insights for future liposomal therapy and improved patient outcomes.
ACTA BIOMATERIALIA
(2023)
Review
Chemistry, Applied
Mehrab Pourmadadi, Shima Ostovar, Mohammad Mahdi Eshaghi, Maryam Rajabzadeh-Khosroshahi, Sara Safakhah, Suresh Ghotekar, Abbas Rahdar, Ana M. Diez-Pascual
Summary: Metal-organic frameworks (MOFs) have attracted attention for their flexibility, tunable porosity, and easy functionalization, and have been investigated as carriers for therapeutics delivery to cancerous organs due to their high encapsulating capacity, controlled cargo release, biodegradability, and biocompatibility. Various methods have been used to fabricate MOFs, and post-synthetic modification is commonly employed to functionalize them. This literature review focuses on drug-loaded MOFs for cancer detection and treatment, as well as bacterial, fungal, and viral infections, describing different types of MOFs as drug carriers and biosensing platforms. The review also discusses future perspectives and challenges, particularly in cancer therapy.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Sonia Fathi-Karkan, Shekoufeh Mirinejad, Fulden Ulucan-Karnak, Mahwash Mukhtar, Hossein Ghahramani Almanghadim, Saman Sargazi, Abbas Rahdar, Ana M. Diez-Pascual
Summary: Chitosan nanoparticles (CS NPs) combine the beneficial properties of natural polymers and nanoscale particles, with potential applications in biomedical fields such as bioimaging and drug delivery. Aptamer-conjugated CS NPs can improve the efficacy of conventional therapies and have antibacterial and antiviral properties. This review aims to provide an overview of the bioapplications of aptamer-conjugated CS NPs and their potential future directions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Sahand Parvaneh, Mehrab Pourmadadi, Majid Abdouss, Seied Ali Pourmousavi, Fatemeh Yazdian, Abbas Rahdar, Ana M. Diez-Pascual
Summary: Nanocomposite hydrogels composed of CMC/starch/RGO were synthesized and encapsulated in double nanoemulsions for pH-responsive delivery of curcumin. The nanocarriers exhibited improved drug loading and entrapment efficiencies compared to previous systems. The release experiments showed pH-responsiveness and faster release at lower pH. The developed nanocarriers were stable, uniform, and effective for sustained curcumin release.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Hemil S. Patel, Anju Kunjadiya, Abbas Rahdar, Rakesh K. Sharma
Summary: In this study, a mixed polymeric nanomicellar formulation composed of Pluronic P123, Pluronic F68, and phosphatidylcholine (PC) was designed and investigated as nanovehicles for improving the bioavailability of curcumin (CUR). The formulation showed excellent compatibility and stability, and exhibited powerful antibacterial and antifungal properties. These results suggest that the CUR-PFPC mixed polymeric nanomicellar formulation can be considered as a novel nanovehicle for hydrophobic antimicrobial drugs.
JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS
(2023)
Review
Pharmacology & Pharmacy
Mehrab Pourmadadi, Maryam Rajabzadeh-Khosroshahi, Mohammad Mahdi Eshaghi, Erfan Rahmani, Hamidreza Motasadizadeh, Rabia Arshad, Abbas Rahdar, Sadanand Pandey
Summary: In biomedical engineering, researchers are studying the modification of TiO2 (titania) to enhance its physiochemical properties. This comprehensive review focuses on the potential applications of nanoscale TiO2 and its nanocomposites in biomedical research, specifically in cancer therapeutics. The use of titania-based nanomaterials in biosensors, particularly in the electrochemical field, has been widely explored. Various bioimaging techniques, such as FL, PA, CT, PET, MR, and multi-mode imaging, have been evaluated for their applicability. Nanoscale titania has also emerged as a popular candidate for cancer treatment methods including phototherapy, chemotherapy, and microwave hyperthermia. Finally, a multifunctional nanoplatform combining different treatment methods has been developed for cancer treatment.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Mahmood Barani, Mohammad Reza Hajinezhad, Sheida Shahraki, Shekoufeh Mirinejad, Mahtab Razlansari, Saman Sargazi, Abbas Rahdar, Ana M. Diez-Pascual
Summary: The introduction of innovative medications such as proteasome inhibitors (PIs) has significantly increased the response rate and overall survival of cancer patients. In this study, novel nickel-based metal-organic frameworks (Ni-MOFs) loaded with the second-generation PI carfilzomib (CFZ) were developed and demonstrated to have high loading efficiency and controlled release behavior. The CFZ-loaded Ni-MOFs exhibited higher cytotoxic effects against cancer cells compared to free CFZ and showed potential as promising carriers for targeted drug delivery. Rating: 9 out of 10.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Materials Science, Ceramics
Shraddha Shinde, Shradha Parjane, Harshada Turakane, Parita Basnet, Rajeshwari Oza, Yogita Abhale, Shreyas Pansambal, Kuan Shiong Khoo, Abbas Rahdar, Suresh Ghotekar
Summary: Bio-waste material-assisted nanomaterials synthesis is a newer aspect of modern nanotechnology. In this report, the green fabrication of Cu/CuO/Cu2O NPs using groundnut shell extract was studied. Diverse characterization techniques confirmed the synthesis of the NPs, and their biomedical properties were assessed, including anticancer efficacy and antioxidant properties.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Article
Materials Science, Ceramics
Suresh Ghotekar, Parita Basnet, Kun-Yi Andrew Lin, Abbas Rahdar, Alejandro Perez Larios, Vimal Gandhi, Rajeshwari Oza
Summary: In this study, cerium vanadate nanoparticles (CeVO4 NPs) were fabricated for the first time using Azadirachta indica leaves extract as a natural fuel, providing a green approach. The textural properties, including structure, topology, and optical characteristics, of the synthesized CeVO4 NPs were analyzed using various techniques. The results showed that the NPs had a pseudo-spherical shape with a size of 43 nm. Furthermore, the anticancer performance against HeLa cancer cell lines and antioxidant efficacy of the biosynthesized CeVO4 NPs were evaluated. This study presents a facile, safe, cheap, rapid, and greener method for producing CeVO4 NPs, which has potential for clinical applications.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Article
Materials Science, Ceramics
Amir Hossein Khodabandehloo, Mehrab Pourmadadi, Amin Shamsabadipour, Hadis Langari, Amanda-Lee Manicum, Abbas Rahdar, Francesco Baino
Summary: Various diseases during cancer surgery, including infections, trauma, and tumor resections, can lead to bone damage or skeletal defects. These defects cannot heal spontaneously due to medical conditions such as diabetes, hormone-related problems, and autoimmune disorders. Bone-tissue engineering has emerged as a solution to these challenges, utilizing strategies like studying bone structures, employing growth factors, scaffolds, and biomaterial-centered regenerative approaches. This study reviews recent bone-tissue-engineering strategies using 2D materials such as graphene and its derivatives, black phosphorus, and MXenes, which show great potential in regenerative medicine.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2023)
Article
Water Resources
Soumya Ghosh, Shabnam Ahmadi, Alhadji Malloum, Leili Mohammadi, Chinenye Adaobi Igwegbe
Summary: Dyes in wastewater are major pollutants that pose significant environmental challenges, contaminating surface and groundwater and endangering human health and ecological balance. This study examines the effectiveness of nanoscale zero-valent iron (nZVI) in removing Eosin Y (Eo-Y) and Erythrosin B (Er-B) from aqueous solutions. Through experiments and modeling, the research demonstrates the remarkable adsorption capacity of nZVI and describes the chemisorption mechanisms, adsorption isotherm models, and molecular interactions involved in the process.
SUSTAINABLE WATER RESOURCES MANAGEMENT
(2023)
Article
Environmental Sciences
Roghaieh Holghoomi, Siavash Hosseini Sarghein, Jalil Khara, Bahman Hosseini, Abbas Rahdar, George Z. Kyzas
Summary: The aim of this research was to study the effect of different concentrations of functionalized multi-walled carbon nanotubes on the phenol and flavonoid content, antioxidant capacity, H2O2 content, reactive oxygen species detection, antioxidant enzyme activity, and volatile compound concentration of basil. The highest content of total phenol, flavonoid, anthocyanin, antioxidant capacity, and hydrogen peroxide were observed in the 200 mg/l functionalized carbon nanotube treatment. The highest percentage of certain compounds was observed at 150 mg/l and 100 mg/l of functionalized carbon nanotube. Overall, the use of functionalized carbon nanotubes as a stimulant increased the antioxidant capacity and secondary metabolite content of basil.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Chinenye Adaobi Igwegbe, Christopher Chiedozie Obi, Paschal Enyinanya Ohale, Shabnam Ahmadi, Okechukwu Dominic Onukwuli, Joseph Tagbo Nwabanne, Andrzej Bialowiec
Summary: This study investigated the modeling and optimization of electrocoagulation-flocculation (ECF) for the recovery of aquaculture effluent (AQE) using aluminum electrodes. The response surface methodology (RSM), artificial neural network (ANN), and adaptive neuro-fuzzy inference system (ANFIS) were employed for modeling, while the numerical RSM and genetic algorithm (GA) were used for optimization. The kinetics of the ECF process were also studied to understand its mechanism. The results showed that ANFIS performed the best in terms of prediction accuracy, and ANFIS-GA achieved the highest turbidity removal efficiency. The Elovich kinetic model had the best correlation with experimental data, indicating that electrostatic interaction governed the ECF process. This study demonstrated the effective modeling and optimization of AQE treatment using ECF, with ANFIS > ANN > RSM and ANFIS-GA > ANN-GA > RSM in terms of performance.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Cell Biology
Zahra Keramati, Gholamreza Motalleb, Abbas Rahdar, Mohammad Amin Kerachian
Summary: This study investigated the effect of co-incubation of 5-FU and gum-based cerium oxide nanoparticles (Ceo-2-XG) on the apoptosis and IC50 of Caco-2 cancer cells. The synthesized Ceo-2-XG nanoparticles were characterized using various techniques. The results showed that co-incubation of 5-FU and Ceo-2-XG nanoparticles significantly increased apoptosis and had a higher antiproliferative activity compared to 5-FU alone.
Review
Materials Science, Multidisciplinary
Saman Sargazi, Mahtab Ghasemi Toudeshkchouei, Abbas Rahdar, Aisha Rauf, Soheil Amani, Muhammad Bilal, Razieh Behzadmehr, Ana M. Diez-Pascual, Francesco Baino
Summary: As a major global cause of liver damage, non-alcoholic fatty liver disease (NAFLD) is associated with excessive hepatocellular lipid accumulation, elevated hepatic enzymes, and fibrotic evidence. Nanotechnology has revolutionized the synthesis of nanostructures for imaging, diagnosis, and treatment of diseases, including NAFLD. Loading drugs into nanocarriers is a promising strategy for extending their circulating time and treating NAFLD. Various nanostructures, such as inorganic nanoparticles, organic-based nanoparticles, metallic nanocarriers, and lipid-based nanocarriers, have been designed and shown significant effects on glucose/lipid levels and liver function indices in NAFLD treatment. However, limitations exist for their use as diagnostic agents. This review aims to discuss recent advancements in nanomedicine for the early diagnosis, treatment, and prognosis of NAFLD.
IRANIAN JOURNAL OF MATERIALS SCIENCE AND ENGINEERING
(2023)