Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs

Title
Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs
Authors
Keywords
HIV infection, Protease inhibitors, Indinavir free base, Pure drug Nanoparticle-in-Microparticle Delivery System (NiMDS), Mucoadhesion, Oral bioavailability
Journal
BIOMATERIALS
Volume 37, Issue -, Pages 383-394
Publisher
Elsevier BV
Online
2014-10-25
DOI
10.1016/j.biomaterials.2014.10.026

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