- Home
- Publications
- Publication Search
- Publication Details
Title
Direct reprogramming into interneurons: potential for brain repair
Authors
Keywords
Transdifferentiation, Viral injections, Neuronal conversion, Intracerebral injections, Mice, Cell therapy, Parvalbumin, Neurodegenerative diseases, Neuropsychiatric disorders, Dopamine, iPSC, ESCs, iNs
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-27
DOI
10.1007/s00018-019-03193-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion
- (2019) Taito Matsuda et al. NEURON
- Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons
- (2019) Chongyuan Luo et al. eLife
- Region-Restrict Astrocytes Exhibit Heterogeneous Susceptibility to Neuronal Reprogramming
- (2019) Xin Hu et al. Stem Cell Reports
- Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease
- (2019) Elena P. Moreno-Jiménez et al. NATURE MEDICINE
- Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons
- (2019) Joseph Herdy et al. eLife
- Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program
- (2018) Marisa Karow et al. NATURE NEUROSCIENCE
- Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer’s Disease
- (2018) Magdalena Martinez-Losa et al. NEURON
- Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn
- (2018) Allen C. Dickie et al. PAIN
- Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain
- (2018) Wenze Niu et al. Stem Cell Reports
- Altered postnatal maturation of striatal GABAergic interneurons in a phenotypic animal model of dystonia
- (2017) Christoph Bode et al. EXPERIMENTAL NEUROLOGY
- Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons
- (2017) Marc S. Weinberg et al. MOLECULAR THERAPY
- Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model
- (2017) Tetsuhiro Kikuchi et al. NATURE
- Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model
- (2017) Pia Rivetti di Val Cervo et al. NATURE BIOTECHNOLOGY
- Neural grafting for Parkinson's disease: challenges and prospects
- (2017) ThomasB Stoker et al. Neural Regeneration Research
- Lineage Reprogramming of Astroglial Cells from Different Origins into Distinct Neuronal Subtypes
- (2017) Malek Chouchane et al. Stem Cell Reports
- Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons
- (2017) Maria Pereira et al. Stem Cell Reports
- NEUROD1 Instructs Neuronal Conversion in Non-Reactive Astrocytes
- (2017) Rebecca Brulet et al. Stem Cell Reports
- Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming
- (2016) Sergio Gascón et al. Cell Stem Cell
- Conversion of Fibroblasts to Parvalbumin Neurons by One Transcription Factor, Ascl1, and the Chemical Compound Forskolin
- (2016) Zixiao Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brain repair and reprogramming: the route to clinical translation
- (2016) S. Grealish et al. JOURNAL OF INTERNAL MEDICINE
- Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq
- (2016) Barbara Treutlein et al. NATURE
- GABAergic Interneurons in the Neocortex: From Cellular Properties to Circuits
- (2016) Robin Tremblay et al. NEURON
- Interneuron Progenitor Transplantation to Treat CNS Dysfunction
- (2016) Muhammad O. Chohan et al. Frontiers in Neural Circuits
- Electrical coupling regulates layer 1 interneuron microcircuit formation in the neocortex
- (2016) Xing-Hua Yao et al. Nature Communications
- Direct Induction and Functional Maturation of Forebrain GABAergic Neurons from Human Pluripotent Stem Cells
- (2016) Alfred Xuyang Sun et al. Cell Reports
- Simultaneous effects on parvalbumin-positive interneuron and dopaminergic system development in a transgenic rat model for sporadic schizophrenia
- (2016) Hannah Hamburg et al. Scientific Reports
- Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders
- (2016) Ravit Hadar et al. Scientific Reports
- Nanogrooved substrate promotes direct lineage reprogramming of fibroblasts to functional induced dopaminergic neurons
- (2015) Junsang Yoo et al. BIOMATERIALS
- Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming
- (2015) Gaia Colasante et al. Cell Stem Cell
- Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes
- (2015) Giacomo Masserdotti et al. Cell Stem Cell
- Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons
- (2015) Lei Zhang et al. Cell Stem Cell
- Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects
- (2015) Jerome Mertens et al. Cell Stem Cell
- Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells
- (2015) J. A. Tyson et al. DEVELOPMENT
- Striatal astrocytes produce neuroblasts in an excitotoxic model of Huntington's disease
- (2015) G. Nato et al. DEVELOPMENT
- How to make a midbrain dopaminergic neuron
- (2015) E. Arenas et al. DEVELOPMENT
- Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo
- (2015) Y. Liu et al. JOURNAL OF NEUROSCIENCE
- In vivo reprogramming for tissue repair
- (2015) Christophe Heinrich et al. NATURE CELL BIOLOGY
- Moving Stem Cells to the Clinic: Potential and Limitations for Brain Repair
- (2015) Julius A. Steinbeck et al. NEURON
- A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior
- (2015) Eyal Vardy et al. NEURON
- The neuropathology of schizophrenia: A selective review of past studies and emerging themes in brain structure and cytoarchitecture
- (2015) K. Bakhshi et al. NEUROSCIENCE
- Chemokine receptors and cortical interneuron dysfunction in schizophrenia
- (2015) David W. Volk et al. SCHIZOPHRENIA RESEARCH
- Cell cycle and p53 gate the direct conversion of human fibroblasts to dopaminergic neurons
- (2015) Houbo Jiang et al. Nature Communications
- In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry
- (2015) Olof Torper et al. Cell Reports
- SOX2 Reprograms Resident Astrocytes into Neural Progenitors in the Adult Brain
- (2015) Wenze Niu et al. Stem Cell Reports
- Remote control of induced dopaminergic neurons in parkinsonian rats
- (2014) Maria Teresa Dell’Anno et al. JOURNAL OF CLINICAL INVESTIGATION
- Interneuron cell types are fit to function
- (2014) Adam Kepecs et al. NATURE
- Selective conversion of fibroblasts into peripheral sensory neurons
- (2014) Joel W Blanchard et al. NATURE NEUROSCIENCE
- Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts
- (2014) Matheus B. Victor et al. NEURON
- Glial Cells as Progenitors and Stem Cells: New Roles in the Healthy and Diseased Brain
- (2014) Leda Dimou et al. PHYSIOLOGICAL REVIEWS
- Cortical plasticity induced by transplantation of embryonic somatostatin or parvalbumin interneurons
- (2014) Yunshuo Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse
- (2014) J. P. Magnusson et al. SCIENCE
- Interneurons from Embryonic Development to Cell-Based Therapy
- (2014) D. G. Southwell et al. SCIENCE
- DISC1 knockdown impairs the tangential migration of cortical interneurons by affecting the actin cytoskeleton
- (2014) André Steinecke et al. Frontiers in Cellular Neuroscience
- In vivo conversion of astrocytes to neurons in the injured adult spinal cord
- (2014) Zhida Su et al. Nature Communications
- Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain
- (2014) Maria Pereira et al. Scientific Reports
- Sox2-Mediated Conversion of NG2 Glia into Induced Neurons in the Injured Adult Cerebral Cortex
- (2014) Christophe Heinrich et al. Stem Cell Reports
- Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation
- (2014) Daisuke Doi et al. Stem Cell Reports
- Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog
- (2013) Swetlana Sirko et al. Cell Stem Cell
- Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells
- (2013) Asif M. Maroof et al. Cell Stem Cell
- Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development
- (2013) Cory R. Nicholas et al. Cell Stem Cell
- In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model
- (2013) Ziyuan Guo et al. Cell Stem Cell
- In vivo reprogramming of astrocytes to neuroblasts in the adult brain
- (2013) Wenze Niu et al. NATURE CELL BIOLOGY
- Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells
- (2013) Yan Liu et al. Nature Protocols
- Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo
- (2013) Ira Espuny-Camacho et al. NEURON
- Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism
- (2013) D. Rylander et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generation of induced neurons via direct conversion in vivo
- (2013) O. Torper et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Environmental impact on direct neuronal reprogramming in vivo in the adult brain
- (2013) Andrew Grande et al. Nature Communications
- Development and specification of GABAergic cortical interneurons
- (2013) Corey Kelsom et al. Cell and Bioscience
- Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors
- (2012) Dong Wook Han et al. Cell Stem Cell
- Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells
- (2012) Marc Thier et al. Cell Stem Cell
- Reprogramming of Pericyte-Derived Cells of the Adult Human Brain into Induced Neuronal Cells
- (2012) Marisa Karow et al. Cell Stem Cell
- Interneuron dysfunction in psychiatric disorders
- (2012) Oscar Marín NATURE REVIEWS NEUROSCIENCE
- The Logic of Inhibitory Connectivity in the Neocortex
- (2012) Elodie Fino et al. NEUROSCIENTIST
- Efficient induction of functional neurons from adult human fibroblasts
- (2011) Ulrich Pfisterer et al. CELL CYCLE
- Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts
- (2011) Jongpil Kim et al. Cell Stem Cell
- Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons
- (2011) Esther Y. Son et al. Cell Stem Cell
- Context-specific -to- -cell reprogramming by forced Pdx1 expression
- (2011) Y.-P. Yang et al. GENES & DEVELOPMENT
- Selective Inhibition of Striatal Fast-Spiking Interneurons Causes Dyskinesias
- (2011) A. H. Gittis et al. JOURNAL OF NEUROSCIENCE
- Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
- (2011) Massimiliano Caiazzo et al. NATURE
- Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease
- (2011) Sonja Kriks et al. NATURE
- Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors
- (2011) Pengyu Huang et al. NATURE
- Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
- (2011) Sayaka Sekiya et al. NATURE
- Induction of human neuronal cells by defined transcription factors
- (2011) Zhiping P. Pang et al. NATURE
- Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
- (2011) Jem A. Efe et al. NATURE CELL BIOLOGY
- Efficient Conversion of Astrocytes to Functional Midbrain Dopaminergic Neurons Using a Single Polycistronic Vector
- (2011) Russell C. Addis et al. PLoS One
- Direct conversion of human fibroblasts to dopaminergic neurons
- (2011) U. Pfisterer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GABAergic Neuronal Precursor Grafting: Implications in Brain Regeneration and Plasticity
- (2011) Manuel Alvarez Dolado et al. NEURAL PLASTICITY
- Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors
- (2010) Masaki Ieda et al. CELL
- Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons
- (2010) Bernardo Rudy et al. Developmental Neurobiology
- Direct conversion of human fibroblasts to multilineage blood progenitors
- (2010) Eva Szabo et al. NATURE
- Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss
- (2010) Fabrizio Thorel et al. NATURE
- Direct conversion of fibroblasts to functional neurons by defined factors
- (2010) Thomas Vierbuchen et al. NATURE
- Direct reprogramming of fibroblasts into epiblast stem cells
- (2010) Dong Wook Han et al. NATURE CELL BIOLOGY
- Optogenetics
- (2010) Karl Deisseroth NATURE METHODS
- Directing Astroglia from the Cerebral Cortex into Subtype Specific Functional Neurons
- (2010) Christophe Heinrich et al. PLOS BIOLOGY
- Physiology and Pharmacology of Striatal Neurons
- (2009) Anatol C. Kreitzer Annual Review of Neuroscience
- Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome
- (2009) Yuko Kataoka et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Common circuit defect of excitatory-inhibitory balance in mouse models of autism
- (2009) Nadine Gogolla et al. Journal of Neurodevelopmental Disorders
- Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
- (2009) Vikaas S. Sohal et al. NATURE
- Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals
- (2008) Mototsugu Eiraku et al. Cell Stem Cell
- Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage
- (2008) Y. Elkabetz et al. GENES & DEVELOPMENT
- Progeny of Olig2-Expressing Progenitors in the Gray and White Matter of the Adult Mouse Cerebral Cortex
- (2008) L. Dimou et al. JOURNAL OF NEUROSCIENCE
- In vivo reprogramming of adult pancreatic exocrine cells to β-cells
- (2008) Qiao Zhou et al. NATURE
- An intrinsic mechanism of corticogenesis from embryonic stem cells
- (2008) Nicolas Gaspard et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started