T-cell receptor sequencing demonstrates persistence of virus-specific T cells after antiviral immunotherapy

Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation

(2017) Ifigeneia Tzannou et al.   JOURNAL OF CLINICAL ONCOLOGY

Identifying specificity groups in the T cell receptor repertoire

(2017) Jacob Glanville et al.   NATURE

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

(2017) Mikhail Shugay et al.   NUCLEIC ACIDS RESEARCH

T cells for viral infections after allogeneic hematopoietic stem cell transplant

(2016) Catherine M. Bollard et al.   BLOOD

How I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipients

(2016) F. El Chaer et al.   BLOOD

Virus-specific T-cell banks for 'off the shelf' adoptive therapy of refractory infections

(2016) R J O'Reilly et al.   BONE MARROW TRANSPLANTATION

Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific T lymphocytes

(2016) Swati Naik et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Specific T cells for the treatment of cytomegalovirus and/or adenovirus in the context of hematopoietic stem cell transplantation

(2016) Rita Creidy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Public T cell receptors confer high-avidity CD4 responses to HIV controllers

(2016) Daniela Benati et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of memory T cell subsets for adoptive immunotherapy

(2016) Dirk H. Busch et al.   SEMINARS IN IMMUNOLOGY

Immunotherapy with Donor T Cells Sensitized with Overlapping Pentadecapeptides for Treatment of Persistent Cytomegalovirus Infection or Viremia

(2015) Guenther Koehne et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire

(2015) Yvonne Suessmuth et al.   BLOOD

CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo

(2015) Patrick J. Hanley et al.   Science Translational Medicine

The time is now: moving toward virus-specific T cells after allogeneic hematopoietic stem cell transplantation as the standard of care

(2014) Francesco Saglio et al.   CYTOTHERAPY

Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development

(2014) Xiaomin Yu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors

(2014) Alena Gros et al.   JOURNAL OF CLINICAL INVESTIGATION

Activity of Broad-Spectrum T Cells as Treatment for AdV, EBV, CMV, BKV, and HHV6 Infections after HSCT

(2014) A. Papadopoulou et al.   Science Translational Medicine

Donor-derived CMV-specific T cells reduce the requirement for CMV-directed pharmacotherapy after allogeneic stem cell transplantation

(2013) E. Blyth et al.   BLOOD

Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

(2013) A. M. Leen et al.   BLOOD

Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant

(2013) Ulrike Gerdemann et al.   MOLECULAR THERAPY

Combining Next-Generation Sequencing and Immune Assays: A Novel Method for Identification of Antigen-Specific T Cells

(2013) Mark Klinger et al.   PLoS One

Rapid Intrahost Evolution of Human Cytomegalovirus Is Shaped by Demography and Positive Selection

(2013) Nicholas Renzette et al.   PLoS Genetics

Rapid Salvage Treatment With Virus-Specific T Cells for Therapy-Resistant Disease

(2012) M. Uhlin et al.   CLINICAL INFECTIOUS DISEASES

Methods for diversity and overlap analysis in T-cell receptor populations

(2012) Grzegorz A. Rempala et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Rapidly Generated Multivirus-specific Cytotoxic T Lymphocytes for the Prophylaxis and Treatment of Viral Infections

(2012) Ulrike Gerdemann et al.   MOLECULAR THERAPY

TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

(2012) Huabiao Chen et al.   NATURE IMMUNOLOGY

Adoptive immunotherapy with unselected or EBV-specific T cells for biopsy-proven EBV+ lymphomas after allogeneic hematopoietic cell transplantation

(2011) E. Doubrovina et al.   BLOOD

Escape from highly effective public CD8+ T-cell clonotypes by HIV

(2011) M. C. Iglesias et al.   BLOOD

Management of multidrug-resistant viruses in the immunocompromised host

(2011) Rob S. Sellar et al.   BRITISH JOURNAL OF HAEMATOLOGY

Directly Selected Cytomegalovirus-Reactive Donor T Cells Confer Rapid and Safe Systemic Reconstitution of Virus-Specific Immunity Following Stem Cell Transplantation

(2010) K. S. Peggs et al.   CLINICAL INFECTIOUS DISEASES

Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation

(2009) A. M. Leen et al.   BLOOD

How we treat cytomegalovirus in hematopoietic cell transplant recipients

(2009) M. Boeckh et al.   BLOOD

Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients

(2009) H. E. Heslop et al.   BLOOD