Anticancer effect of berberine based on experimental animal models of various cancers: a systematic review and meta-analysis

Berberine and zinc oxide-based nanoparticles for the chemo-photothermal therapy of lung adenocarcinoma

(2018) Sungyun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oncosis-like cell death is induced by berberine through ERK1/2-mediated impairment of mitochondrial aerobic respiration in gliomas

(2018) Yuxue Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Berberine suppresses growth and metastasis of endometrial cancer cells via miR-101/COX-2

(2018) Yu Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Berberine Suppresses Cell Motility Through Downregulation of TGF-β1 in Triple Negative Breast Cancer Cells

(2018) Sangmin Kim et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Relationship Between Metabolic Disorders and Breast Cancer Incidence and Outcomes. Is There a Preventive and Therapeutic Role for Berberine?

(2018) MASSIMILIANO CAZZANIGA et al.   ANTICANCER RESEARCH

Antitumor Effects of Berberine against EGFR, ERK1/2, P38 and AKT in MDA-MB231 and MCF-7 Breast Cancer Cells Using Molecular Modelling and in Vitro Study

(2018) Parham Jabbarzadeh Kaboli et al.   Pharmacological Reports

Berberine Attenuated Proliferation, Invasion and Migration by Targeting the AMPK/HNF4α/WNT5A Pathway in Gastric Carcinoma

(2018) Qian Hu et al.   Frontiers in Pharmacology

Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells

(2017) H Ruan et al.   ONCOGENE

Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism

(2017) Chao Wang et al.   ONCOLOGY REPORTS

Berberine inhibits androgen synthesis by interaction with aldo-keto reductase 1C3 in 22Rv1 prostate cancer cells

(2016) Jing Li et al.   ASIAN JOURNAL OF ANDROLOGY

Synergistic anti-cancer effects of galangin and berberine through apoptosis induction and proliferation inhibition in oesophageal carcinoma cells

(2016) Kewei Ren et al.   BIOMEDICINE & PHARMACOTHERAPY

Berberine modulates cisplatin sensitivity of human gastric cancer cells by upregulation of miR-203

(2016) He-Yi You et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric cancer MGC 803 cell proliferation and IL-8 secretion in vitro and in vivo

(2016) Hong-Li Li et al.   Molecular Medicine Reports

Effect of evodiamine and berberine on miR-429 as an oncogene in human colorectal cancer

(2016) Bin Wen et al.   OncoTargets and Therapy

Berberine Increases Doxorubicin Sensitivity by Suppressing STAT3 in Lung Cancer

(2015) Ting Zhu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma

(2015) Chi Man Tsang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Berberine, a natural compound, suppresses Hedgehog signaling pathway activity and cancer growth

(2015) Juan Wang et al.   BMC CANCER

Antiangiogenic and antitumor activities of berberine derivative NAX014 compound in a transgenic murine model of HER2/neu-positive mammary carcinoma

(2015) Elisa Pierpaoli et al.   CARCINOGENESIS

Sidestream dark field videomicroscopy forin vivoevaluation of vascularization and perfusion of mammary tumours in HER2/neu transgenic mice

(2015) Elisa Damiani et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Berberine induces apoptosis by suppressing the arachidonic acid metabolic pathway in hepatocellular carcinoma

(2015) JING LI et al.   Molecular Medicine Reports

Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil

(2015) Arvind Pandey et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Metformin and Berberine Prevent Olanzapine-Induced Weight Gain in Rats

(2014) Yueshan Hu et al.   PLoS One

Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts

(2013) Chi Man Tsang et al.   BMC CANCER

Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo

(2013) Yuchen Cai et al.   Journal of Natural Medicines

Correction: Identification of Proteins Sensitive to Thermal Stress in Human Neuroblastoma and Glioma Cell Lines

(2013) Guilian Xu et al.   PLoS One

Berberine enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast cancer

(2013) ALAA REFAAT et al.   Oncology Letters

Synthesis and Cytotoxicity Evaluation of 13-n-Alkyl Berberine and Palmatine Analogues as Anticancer Agents

(2012) Lei Zhang et al.   MOLECULES

Lipid-lowering effect of berberine in human subjects and rats

(2012) Yueshan Hu et al.   PHYTOMEDICINE

Animal Research: Reporting in vivo Experiments—The ARRIVE Guidelines

(2011) Carol Kilkenny et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dietary administration of berberine or Phellodendron amurense extract inhibits cell cycle progression and lung tumorigenesis

(2010) Michael A. James et al.   MOLECULAR CARCINOGENESIS

Berberine inhibits adipogenesis in high-fat diet-induced obesity mice

(2009) Yueshan Hu et al.   FITOTERAPIA

Berbamine induces Fas-mediated apoptosis in human hepatocellular carcinoma HepG2 cells and inhibits its tumor growth in nude mice

(2009) Guan-Yu Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Berberine inhibits human tongue squamous carcinoma cancer tumor growth in a murine xenograft model

(2009) Yung-Tsuan Ho et al.   PHYTOMEDICINE

Protective effects of berberine on radiation-induced lung injury via intercellular adhesion molecular-1 and transforming growth factor-beta-1 in patients with lung cancer

(2008) Yunfang Liu et al.   EUROPEAN JOURNAL OF CANCER

Treatment of Type 2 Diabetes and Dyslipidemia with the Natural Plant Alkaloid Berberine

(2008) Yifei Zhang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

p53 cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo

(2008) Santosh K. Katiyar et al.   MOLECULAR CARCINOGENESIS