Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis

Title
Discovery and optimization of pyridyl-cycloalkyl-carboxylic acids as inhibitors of microsomal prostaglandin E synthase-1 for the treatment of endometriosis
Authors
Keywords
mPGES-1, PTGES, Pain, Prostaglandin pathway, PGE, 2
Journal
Publisher
Elsevier BV
Online
2019-07-24
DOI
10.1016/j.bmcl.2019.07.007

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