Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling

Published 2019 View Full Article

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Title
Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling
Authors
Keywords
Janus Kinase, JAK, JAK1, JAK2, Interleukin-13, IL-13, Structure-based design, Asthma, Atopic dermatitis
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 29, Issue 12, Pages 1522-1531
Publisher
Elsevier BV
Online
2019-04-05
DOI
10.1016/j.bmcl.2019.04.008

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