Journal
BIOINFORMATICS
Volume 35, Issue 22, Pages 4760-4763Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btz448
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Funding
- European Union [FP7 Marie Curie CIG grant] [631986]
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The Summary: Long non-coding RNAs (lncRNAs) can act as molecular sponge or decoys for an RNA-binding protein (RBP) through their RBP-binding sites, thereby modulating the expression of all target genes of the corresponding RBP of interest. Here, we present a web tool named RBPSponge to explore lncRNAs based on their potential to act as a sponge for an RBP of interest. RBPSponge identifies the occurrences of RBP-binding sites and CLIP peaks on lncRNAs, and enables users to run statistical analyses to investigate the regulatory network between lncRNAs, RBPs and targets of RBPs.
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