Article
Chemistry, Multidisciplinary
Lennart Graewe, Maximilian L. L. Hupfer, Martin Schulz, Atif Mahammed, Zeev Gross, Martin Presselt
Summary: Amphiphilic iron(III) corroles are assembled into well-defined quasi-two-dimensional molecular monolayers at air-water interfaces using the Langmuir-Blodgett (LB) technique. The optical density of the stacks of molecular monolayers allows for photometric detection of nitric oxide (NO) binding. The highest molecular efficiency for NO binding and detection is achieved at the smallest packing densities.
Article
Chemistry, Physical
Yan Nie, Maozhang Tian, Qun Zhang, Lu Wang, Zemin Ji, Xi Chen, Shengjian Yang, Wenfeng Song, Chunxian Wu, Hualong Xu, Meiwen Cao
Summary: The controlled fabrication of uniform graphene oxide (GO) films by Langmuir-Blodgett (LB) method using dialyzed GO sheets smaller than 200 nm allows for well control over the quality of the films. The dialysis procedure removes soluble impurities from the GO sheets to adjust their surface composition and physicochemical properties, ultimately helping to avoid edge folding and stacking during LB assembly and achieve better control over interactions between the GO sheets. This approach enables the successful fabrication of uniform GO films with controlled surface coverage and density, which exhibit high stability and biocompatibility for applications in mediating cell growth and proliferation.
JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Chenfang Sun, Rui Li, Yaru Song, Xiaoqian Jiang, Congcong Zhang, Shanshan Cheng, Wenping Hu
Summary: A novel organic material, BFPA, has been developed for OFET-based biosensors, enabling ultrasensitive determination of AFP in human serum and differentiation between liver cancer patients and healthy individuals.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Applied
Jia-Xin Li, Ji-Jun Xu, Wen-Qi Luo, Chuan-Ming Jin
Summary: Three non-classical amphiphilic phenylazoimidazole derivatives were synthesized and their in-situ molecular assemblies upon coordination with AgNO3 at the air/water interface were investigated. These compounds showed good photochromic properties and formed H-aggregates on the surface despite lacking alkyl chains. The Ag(I)-coordinated 4-PRIM films exhibited supramolecular chirality due to pi-pi stacking between neighboring azophenyl imidazolium units and symmetry breaking in some systems.
Article
Chemistry, Physical
Marystela Ferreira, Shiv K. Sharma, Suraj Paudyal, Roger M. Leblanc
Summary: This article explores the surface chemistry properties of the lactate oxidase (LacOx) enzyme monolayer at the air-subphase interface, finding that it remains active and stable without aggregation or irreversible domains. Spectroscopic experiments provided information on the enzyme's secondary structure conformation and showed that the LB film retains an alpha-helix conformation.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Marek Szablewski, Richard L. Thompson, Lars-Olof Palsson
Summary: Novel fluorescent Langmuir-Blodgett (LB) films have been constructed from different amphiphilic dicynaoquinodimethanes (DADQs), and the relationship between film structure and fluorescence properties, as well as the response of the films to non-fluorescent target analytes, has been studied. The results show that the modulation of fluorescence varies for different films, which can be attributed to restricted non-radiative decays or charge transfer reactions between target analyte and film.
Article
Chemistry, Applied
Qian Shen, Wei Zheng, Fei Han, Jingnan Zuo, Jun Dai, Cuie Tang, Rong Song, Bin Li, Yijie Chen
Summary: The air-water interfacial properties of pea protein isolate (PPI) and Tween 20 (T20) were investigated. The foam prepared with 0.5% PPI and 0.1% T20 showed higher stability and uniform bubble size distribution. Atomic force microscopy (AFM) observations revealed that Tween 20 displaced PPI at the air-water interface, leading to an increased protein quantity in the foam network and improved foam stability. This research enhances understanding of the protein displacement process and can potentially enhance the quality of foam-based foods.
FOOD HYDROCOLLOIDS
(2023)
Review
Polymer Science
Wei-Jie Wang, Xian Xu, Yu Shao, Jian-Wen Liao, Han-Xin Jian, Bing Xue, Shu-Guang Yang
Summary: This article summarizes the findings of fractal growth of giant amphiphiles in Langmuir-Blodgett (LB) films and discusses the effects of molecular structures and operation parameters on the fractal growth patterns. The aim of the study is to understand the basic molecular principle of fractal growth in LB systems.
CHINESE JOURNAL OF POLYMER SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Juan Wang
Summary: This study investigated the effects of potassium ions on the surface properties of Amphotericin B (AmB) using the Langmuir monolayer method. The results showed that potassium ions enhance the influence of AmB on membrane stability at low surface pressures but weaken it at high surface pressures. Potassium ions also significantly interfere with the interaction between AmB and the cholesterol-enriched region.
Article
Chemistry, Physical
Katarzyna Dopierala, Agnieszka Kolodziejczak-Radzimska, Krystyna Prochaska, Teofil Jesionowski
Summary: This study reports on the formation of interfacial films by amphiphilic, incompletely condensed silsesquioxane and enzyme, lipase, and their deposition on zirconium dioxide surface for use as a biocatalyst. The results indicate that this method can achieve high enzymatic activity, with the immobilized lipase showing promising stability and reusability. The strategy of coating zirconia with TCyPOSS film incorporating enzymes shows potential for controlled architecture at a molecular level.
APPLIED SURFACE SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Ki-Wan Jeon
Summary: The study reports the synthesis and fabrication of highly thionated reduced graphene oxide and its LB film, revealing sensitive electronic transport properties and optical characteristics of the film to the thiol content.
Article
Materials Science, Multidisciplinary
Jing Chen, Na Li, Lin Li, Chongling Wang, Dongxue Han, Tifeng Jiao
Summary: Molecular self-assembly is the process in which functional assemblies of different structural components are formed through weak and reversible non-covalent interactions based on molecular recognition. In this study, two special amphiphilic molecules, indocyanine green (ICG) and its derivative (CCS), were combined with two dye molecules for self-assembly using the Langmuir-Blodgett (LB) technique. The ordered LB films showed better optoelectronic properties and hydrophobicity compared to drop-casting films, indicating their potential application in optoelectronic functional ultrathin film devices.
Article
Nanoscience & Nanotechnology
Shan Du, Tiantian He, Guang Yang, Huali Nie
Summary: This study presents a new strategy for surface coating of wigs using a nanocomposite of hair-derived keratin and graphene oxide via the LB technique. Compared to the conventional immersion method, this strategy achieves higher surface coverage and a close-packed structure, resulting in improved performance and durability.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Engineering, Environmental
Wei Deng, Kun Xiong, Nina Ge, Miao Yu, Lin Chen, Jun Wang
Summary: In this study, a novel co-doped zinc ferrite film was prepared for efficient removal of residual tetracycline in the aquatic environment. The interfacial photoelectrocatalytic activities of the CoTiZFO films were significantly improved with the co-doping of Co and Ti. The five-layered LB-CoTiZFO films exhibited the optimal degradation and mineralization rates for tetracycline.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Physical
Pavan K. Narayanam, S. S. Major
Summary: The GO-TiO2 nanocomposite sheets were transferred onto solid substrates using Langmuir-Blodgett method and subjected to heat treatment to obtain rGO-wrapped TiO2 nanostructures. The heat treatment conditions significantly influenced the reduction of GO, crystalline phases of TiO2, and the development of composite nanostructures. Photocatalytic studies showed strong dependence of photo-degradation on the morphology of the nanocomposite sheets.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Engineering, Biomedical
Wenbo Zhang, Luca Bertinetti, Efe Cuma Yavuzsoy, Changyou Gao, Emanuel Schneck, Peter Fratzl
Summary: Physical forces play a crucial role in the development and function of biological tissues. However, the measurement of osmotic pressures in cell and organ culture systems has been challenging. In this study, novel liposomal sensors based on resonance energy transfer (FRET) were developed to accurately measure osmotic pressures in physiological conditions. These sensors were successfully applied in pre-osteoblastic cell culture systems, paving the way for in situ osmotic pressure sensing in biological cultures.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Physical
Matej Kanduc, Cosima Stubenrauch, Reinhard Miller, Emanuel Schneck
Summary: Surfactants play important roles in everyday applications and industrial processes. However, the characteristic time scales of surfactant exchange pose challenges for atomistic molecular dynamics simulations. In this study, a framework combining thermodynamic principles and atomistic MD simulations was introduced, which provided a full thermodynamic description and connected the experimental control parameter with the suitable control parameter in MD simulations. The results showed a semiquantitative agreement between simulation and experimental data, but also highlighted opportunities for improving the current atomistic models in predicting surfactant affinities to aggregates.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
(2023)
Article
Chemistry, Physical
Nayereh Sadat Mousavi, Reinhard Miller, Emanuel Schneck
Summary: An empirical adsorption isotherm model based on fundamental thermodynamic equations of adsorption is presented for the nonionic surfactants CnEOm. The model describes the surface properties of CnEOm better than the original Langmuir adsorption model. The results show that the increase of the alkyl chain length n leads to higher adsorption activity, while the increase of hydrophilic head group given by the number of EO units m leads to better solubility in water and smaller adsorbed amount.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Batuhan Kav, Thomas R. R. Weikl, Emanuel Schneck
Summary: Binding forces between biomolecules are common in nature and can be as weak as a few pico-Newtons (pN). In this study, we used molecular dynamics simulations to measure the forces generated by bonds involving membrane-anchored molecules. Our results demonstrate binding forces of up to 20 pN and support the idea that carbohydrate-carbohydrate interactions are generic.
JOURNAL OF PHYSICAL CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
V. I. Kovalchuk, E. V. Aksenenko, E. Schneck, R. . Miller
Summary: In recent years, significant progress has been made in the understanding of surfactant adsorption at liquid interfaces. New efficient methodologies, particularly interfacial selective optical methods, have been developed to directly access the adsorbed amounts and interfacial layer compositions. Thermodynamic equations of state provide a quantitative framework for describing surfactant interfacial layers, especially at water/oil interfaces. Molecular modeling techniques have also contributed to the understanding of interfacial layer structures. Improving the interrelationships between these aspects is a challenge for current and future research, with particular focus on dilational interfacial rheology studies.
Article
Chemistry, Multidisciplinary
Alexander Baer, Ingo Hoffmann, Najet Mahmoudi, Alexandre Poulhazan, Matthew J. Harrington, Georg Mayer, Stephan Schmidt, Emanuel Schneck
Summary: To understand the mechanoresponsive behavior of the bio-adhesive slime, the nanostructural organization of its components was studied using small-angle scattering with neutrons and X-rays. It was found that the majority of slime proteins exist freely in solution, while only less than 10% are contained in nanoglobules. Comparing scattering data of slime re-hydrated with light and heavy water revealed that the majority of lipids are contained in nanoglobules with homogeneous distribution. Vibrating mechanical impact without air did not lead to fiber formation, suggesting that interfacial phenomena and directional shearing are required for fiber formation.
Article
Chemistry, Physical
Miriam Grava, Mohd Ibrahim, Akhil Sudarsan, Julio Pusterla, Julian Philipp, Joachim O. Raedler, Nadine Schwierz, Emanuel Schneck
Summary: The protonation degree and lipid packing of ionizable lipids play crucial roles in the performance of lipid-based nanoparticles, and a combination of molecular dynamics simulations and experimental measurements can provide valuable insights for further predictive modeling.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Multidisciplinary Sciences
Marin Sako, Fabio Staniscia, Emanuel Schneck, Roland R. Netz, Matej Kanduc
Summary: This study reveals the conditions for stable lipid monolayer formation in aqueous solutions and water/alcohol mixtures through molecular dynamics simulations and thermodynamic principles. The wetting contact angle of the solvent on the surface is found to be the chief descriptor of the adsorption free energy of monolayers. In aqueous media, theta(ads) falls into a narrow range of around 60 to 70 degrees and is weakly dependent on surface chemistry. Addition of small amounts of alcohol lowers theta(ads) and facilitates monolayer formation on hydrophilic solid surfaces.
Article
Chemistry, Multidisciplinary
Cristina Stefaniu, Christian Woelk, Victoria M. Latza, Andrei Chumakov, Gerald Brezesinski, Emanuel Schneck
Summary: Synthetic amino lipids are utilized in a new way to produce cross-linked stable one-molecule-thin films for future applications in materials. The films are created as Langmuir monolayers at the air/water interface and cross-linked through dynamic imine chemistry. Surface-sensitive techniques such as X-ray diffraction and microscopy are employed to monitor the cross-linking process and film characteristics. The resulting films exhibit mechanically self-supported nanosheets with area dimensions over several micrometers, serving as a visual proof of successful cross-linking.
NANOSCALE ADVANCES
(2023)
Article
Chemistry, Physical
Richard A. Campbell, Talmira Kairaliyeva, Svetlana Santer, Emanuel Schneck, Reinhard Miller
Summary: In this study, the interfacial composition during and after the interactions of a saturated atmosphere of oil vapor with soluble surfactant solutions at a planar water/air interface was directly resolved. The experiments revealed the balance between cooperativity and competition of the components at the interface.
COLLOIDS AND INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Julio Pusterla, Ernesto Scoppola, Christian Appel, Tetiana Mukhina, Chen Shen, Gerald Brezesinski, Emanuel Schneck
Summary: This study investigates the characteristics of lipid bilayers adsorbed to soft air/water interfaces functionalized with amphiphilic Langmuir monolayers. The results show that chain-ordered lipid bilayers have significantly different structural features compared to regular Langmuir monolayers. This suggests that bilayers at air/water interfaces are well suited for fundamental studies in the field of membrane biophysics.
Review
Chemistry, Physical
Xiuying Qiao, Reinhard Miller, Emanuel Schneck, Kang Sun
Summary: Like other proteins, silk fibroin can stabilize foam by adsorbing at the air/water interface and forming water-insoluble viscoelastic films. The solution conditions play an important role in the molecular adsorption and foaming properties of silk fibroin.
COLLOIDS AND INTERFACES
(2022)
Article
Chemistry, Physical
Tetiana Mukhina, Georg Pabst, Jean-Marie Ruysschaert, Gerald Brezesinski, Emanuel Schneck
Summary: In this study, the properties of OL with saturated C14 alkyl chains in mono- and bilayers were investigated using various techniques. It was found that OL has a greater tendency to form ordered structures compared to PEL and can even form a molecular superlattice. These findings indicate that OL and PEL behave differently in different types of membranes.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Chemistry, Physical
Tetiana Mukhina, Gerald Brezesinski, Chen Shen, Emanuel Schneck
Summary: In this study, the phase behavior and structure of lipid monolayers containing glycolipids were investigated using various techniques. Distinct diffraction patterns were observed in glycolipid-enriched domains, revealing a rich phenomenology. The phase behavior was found to be influenced by the structure of the glycolipids.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Physical
Giuseppe Rosario Del Sorbo, Daniel Clemens, Emanuel Schneck, Ingo Hoffmann
Summary: Interactions between polyelectrolytes and oppositely charged surfactants can result in various self-assembled structures. Some of these systems exhibit a significant increase in solution viscosity, which is related to the formation of aggregates connecting multiple polyelectrolyte chains. In this study, the authors investigate a system composed of anionic surfactant sodium monododecyl phosphate and cationic cellulose-based polyelectrolyte JR 400. The hydrophobicity of the surfactant can be controlled by the solution's pH, leading to drastic changes in solution viscosity. The mesoscopic structure of the system and its impact on viscosity are examined using small angle neutron scattering and neutron spin-echo spectroscopy.
Article
Engineering, Biomedical
Lin-Lin Luo, Jie Xu, Bing-Qiao Wang, Chen Chen, Xi Chen, Qiu-Mei Hu, Yu-Qiu Wang, Wan-Yun Zhang, Wan-Xiang Jiang, Xin-Ting Li, Hu Zhou, Xiao Xiao, Kai Zhao, Sen Lin
Summary: A novel AAV serotype, AAVYC5, introduced in this study, showed more efficient transduction into multiple retinal layers compared to AAV2, and enabled successful delivery of anti-angiogenic molecules in mice and non-human primates.
