Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)–Dependent Pulmonary Arterial Hypertension

An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

(2018) Clair Crewe et al.   CELL

Endothelial microparticles are increased in congenital heart diseases and contribute to endothelial dysfunction

(2017) Ze-Bang Lin et al.   Journal of Translational Medicine

Aberrant caveolin-1–mediated Smad signaling and proliferation identified by analysis of adenine 474 deletion mutation (c.474delA) in patient fibroblasts: a new perspective on the mechanism of pulmonary hypertension

(2017) Glenn Marsboom et al.   MOLECULAR BIOLOGY OF THE CELL

The molecular basis of endothelial cell plasticity

(2017) Elisabetta Dejana et al.   Nature Communications

The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways

(2016) Tilman Borggrefe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1

(2015) Mirza Saqib Baig et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nitroglycerin Tolerance in Caveolin-1 Deficient Mice

(2014) Mao Mao et al.   PLoS One

Nitrosation-Dependent Caveolin 1 Phosphorylation, Ubiquitination, and Degradation and its Association with Idiopathic Pulmonary Arterial Hypertension

(2014) Farnaz R. Bakhshi et al.   Pulmonary Circulation

Caveolin-1 Deficiency Induces Spontaneous Endothelial-to-Mesenchymal Transition in Murine Pulmonary Endothelial Cells in Vitro

(2012) Zhaodong Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension

(2012) Eric D. Austin et al.   Circulation-Cardiovascular Genetics

Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

(2012) Iván M. Moya et al.   DEVELOPMENTAL CELL

Pathobiology of pulmonary arterial hypertension and right ventricular failure

(2012) Norbert F. Voelkel et al.   EUROPEAN RESPIRATORY JOURNAL

Nitric oxide–dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition

(2012) Zhenlong Chen et al.   MOLECULAR BIOLOGY OF THE CELL

The WHO Classification of Pulmonary Hypertension: A Case-Based Imaging Compendium

(2012) John J. Ryan et al.   Pulmonary Circulation

Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension

(2011) Rasa Tamosiuniene et al.   CIRCULATION RESEARCH

Mechanisms of disease: pulmonary arterial hypertension

(2011) Ralph T. Schermuly et al.   Nature Reviews Cardiology

Increased Endothelial Cell-Leukocyte Interaction in Murine Schistosomiasis: Possible Priming of Endothelial Cells by the Disease

(2011) Suellen D. S. Oliveira et al.   PLoS One

Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration

(2009) You-Yang Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Filamin A Regulates Caveolae Internalization and Trafficking in Endothelial Cells

(2009) Maria Sverdlov et al.   MOLECULAR BIOLOGY OF THE CELL

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

Transforming growth factor-β1 protects against pulmonary artery endothelial cell apoptosis via ALK5

(2008) Qing Lu   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Increased pulmonary vascular resistance and defective pulmonary artery filling in caveolin-1−/− mice

(2008) Nikolaos A. Maniatis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Genetic Ablation of the Bmpr2 Gene in Pulmonary Endothelium Is Sufficient to Predispose to Pulmonary Arterial Hypertension

(2008) Kwon-Ho Hong et al.   CIRCULATION

Chronic NOS inhibition prevents adverse lung remodeling and pulmonary arterial hypertension in caveolin-1 knockout mice

(2008) Carsten Wunderlich et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS