Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry

Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry

(2019) Xun Bao et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Pharmacokinetic interaction study of novel combination of palbociclib and sorafenib for hepatocellular carcinoma in SD rats

(2019) David Paul et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

CDK4/6 Inhibitors: The Mechanism of Action May Not Be as Simple as Once Thought

(2018) Mary E. Klein et al.   CANCER CELL

An assessment of the impact of green tea extract on palbociclib pharmacokinetics using a validated UHPLC‐QTOF‐MS method

(2018) David Paul et al.   BIOMEDICAL CHROMATOGRAPHY

Development and validation of LC–MS/MS methods for the measurement of ribociclib, a CDK4/6 inhibitor, in mouse plasma and Ringer’s solution and its application to a cerebral microdialysis study

(2017) Ashish Kala et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Cyclin-Dependent Kinase 4/6 Inhibitors for the Treatment of Breast Cancer: A Review of Preclinical and Clinical Data

(2016) Neelima Vidula et al.   Clinical Breast Cancer

Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance

(2016) P. Chen et al.   MOLECULAR CANCER THERAPEUTICS

Treating cancer with selective CDK4/6 inhibitors

(2016) Ben O'Leary et al.   Nature Reviews Clinical Oncology

Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 – 2014)

(2015) Veronika Malínková et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Evolution of targeted therapies in cancer: opportunities and challenges in the clinic

(2015) Sam Santhosh et al.   Future Oncology

Bioanalysis of drug in tissue: current status and challenges

(2012) Y-J Xue et al.   Bioanalysis

Quantitative analysis of PD 0332991 in mouse plasma using automated micro-sample processing and microbore liquid chromatography coupled with tandem mass spectrometry

(2011) Danielle Smith et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Quantitative analysis of PD 0332991 in xenograft mouse tumor tissue by a 96-well supported liquid extraction format and liquid chromatography/mass spectrometry

(2010) Leslie Nguyen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS