Article
Cardiac & Cardiovascular Systems
Alastair Moss, Marwa Daghem, Evangelos Tzolos, Mohammed N. Meah, Kang-Ling Wang, Anda Bularga, Philip D. Adamson, Jacek Kwiecinski, Alison Fletcher, Dana Dawson, Parthiban Arumugam, Nikant Sabharwal, John P. Greenwood, Jon N. Townend, Patrick A. Calvert, James H. F. Rudd, Dan Berman, Johan Verjans, Piotr Slomka, Damini Dey, Laura Forsyth, Lauren Murdoch, Robert J. Lee, Steff Lewis, Nicholas L. Mills, Edwin J. R. van Beek, Michelle C. Williams, Marc R. Dweck, David E. Newby
Summary: In patients with recent myocardial infarction, coronary atherosclerotic plaque activity as assessed by noninvasive imaging was not associated with the primary composite end point, but was associated with an increased risk of cardiovascular death or myocardial infarction.
Article
Radiology, Nuclear Medicine & Medical Imaging
David C. Rotzinger, Virginie Magnin, Allard C. van der Wal, Silke Grabherr, Salah D. Qanadli, Katarzyna Michaud
Summary: Multiphase postmortem CT angiography (PMCTA) can be used to detect plaque enhancement as a surrogate marker of inflammation, providing a noninvasive method for evaluating inflammation in coronary plaques.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Sagit Ben Zekry, Subhashaan Sreedharan, Donghee Han, Stephanie Sellers, Amir A. Ahmadi, Philipp Blanke, Martin Hadamitzky, Yong-Jin Kim, Edoardo Conte, Daniele Andreini, Gianluca Pontone, Matthew J. Budoff, Ilan Gottlieb, Byoung Kwon Lee, Eun Ju Chun, Filippo Cademartiri, Erica Maffei, Hugo Marques, Sanghoon Shin, Jung Hyun Choi, Renu Virmani, Habib Samady, Peter H. Stone, Daniel S. Berman, Jagat Narula, Leslee J. Shaw, Jeroen J. Bax, Jonathon Leipsic, Hyuk-Jae Chang
Summary: This study compared plaque composition and progression between East Asians and Caucasians and identified clinical predictors of plaque progression in East Asians. The results showed that East Asians and Caucasians had similar plaque composition and progression, but East Asians with plaque progression had higher baseline plaque burden and were associated with increased clinical events.
JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY
(2022)
Article
Cardiac & Cardiovascular Systems
A. Maxim Bax, Alexander R. van Rosendael, Xiaoyue Ma, Inge J. van den Hoogen, Umberto Gianni, Sara W. Tantawy, Emma J. Hollenberg, Daniele Andreini, Mouaz H. Al-Mallah, Matthew J. Budoff, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Edoardo Conte, Hugo Marques, Pedro de Araujo Goncalves, Ilan Gottlieb, Martin Hadamitzky, Jonathon A. Leipsic, Erica Maffei, Gianluca Pontone, Sanghoon Shin, Yong-Jin Kim, Byoung Kwon Lee, Eun Ju Chun, Ji Min Sung, Sang-Eun Lee, Renu Virmani, Habib Samady, Peter H. Stone, Daniel S. Berman, James K. Min, Jagat Narula, Fay Y. Lin, Hyuk-Jae Chang, Leslee J. Shaw
Summary: The study found that atherosclerotic plaque burden and composition varied across the major epicardial coronary arteries, with lower burden and different compositions in the LCx compared to the LAD and RCA.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Yang Liu, Shaoyan Liu, Zhizhuang Zhao, Xiang Song, Haixian Qu, Hongbin Liu
Summary: The study revealed a positive correlation between plasma PAG levels and coronary atherosclerotic burden, with higher PAG levels associated with obstructive CAD and high coronary lesion complexity.
Article
Cardiac & Cardiovascular Systems
Sophie E. van Rosendael, Inge J. van den Hoogen, Fay Y. Lin, Daniele Andreini, Mouaz H. Al-Mallah, Matthew J. Budoff, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Edoardo Conte, Hugo Marques, Pedro de Araujo Goncalves, Ilan Gottlieb, Martin Hadamitzky, Jonathon A. Leipsic, Erica Maffei, Gianluca Pontone, Gilbert L. Raff, Sanghoon Shin, Yong-Jin Kim, Byoung Kwon Lee, Eun Ju Chun, Ji Min Sung, Sang-Eun Lee, Renu Virmani, Habib Samady, Peter H. Stone, James K. Min, Jagat Narula, Leslee J. Shaw, Hyuk-Jae Chang, Alexander R. van Rosendael, Jeroen J. Bax
Summary: This study aimed to investigate factors associated with statin nonresponse-defined atherosclerosis progression in patients treated with statins. The results showed that age, diabetes, hypertension, and baseline plaque characteristics were significantly different between patients with and without statin nonresponse. Diabetes, number of high-risk plaque features, and plaque volume were independently associated with statin nonresponse.
JACC-CARDIOVASCULAR IMAGING
(2023)
Article
Critical Care Medicine
Mi Lu, Fang Fang, Zhenjia Wang, Lei Xu, John E. Sanderson, Xiaojun Zhan, Lianping He, Chan Wu, Yongxiang Wei
Summary: The study found that moderate to severe OSA was associated with the presence and burden of coronary plaque, indicating an increased risk of coronary events.
Article
Cardiac & Cardiovascular Systems
A. Maxim Bax, Fay Y. Lin, Alexander R. van Rosendael, Xiaoyue Ma, Yao Lu, Inge J. van den Hoogen, Umberto Gianni, Sara W. Tantawy, Daniele Andreini, Matthew J. Budoff, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Edoardo Conte, Pedro de Araujo Goncalves, Ilan Gottlieb, Martin Hadamitzky, Jonathon A. Leipsic, Erica Maffei, Gianluca Pontone, Gregg Stone, Sanghoon Shin, Yong-Jin Kim, Byoung Kwon Lee, Eun Ju Chun, Ji Min Sung, Sang-Eun Lee, Daniel S. Berman, Jagat Narula, Hyuk-Jae Chang, Leslee J. Shaw
Summary: There are variations in the progression of atherosclerotic plaque between the left circumflex (LCx), right coronary artery (RCA), and left anterior descending (LAD). The LCx has less plaque progression compared to the RCA and LAD, and the LAD is associated with a higher risk of progression to obstructive coronary artery disease.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pengxi Han, Jinyan Tang, Ximing Wang, Yuwen Su, Guijie Li, Kai Deng
Summary: This study aimed to establish a non-invasive and simple screening model for coronary atherosclerosis burden based on blood parameters, in order to reduce unnecessary coronary angiography in patients with coronary artery disease.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Robert W. McGarrah, Maros Ferencik, Stephanie N. Giamberardino, Udo Hoffmann, Borek Foldyna, Julia Karady, Geoffrey S. Ginsburg, William E. Kraus, Pamela S. Douglas, Svati H. Shah
Summary: This study found an association between high-density lipoprotein (HDL) subclasses and high-risk coronary atherosclerotic plaque (HRP), and an association between medium-sized HDL subclasses and major adverse cardiovascular events (MACE). These findings can help stratify the risk of individuals with chest pain and provide insight into the pathobiology of HRP.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mengyuan Jing, Huaze Xi, Hao Zhu, Xiaoyue Zhang, Zheng Xu, Shijie Wu, Jiachen Sun, Liangna Deng, Tao Han, Bin Zhang, Junlin Zhou
Summary: This study aimed to explore the potential relationship between coronary artery inflammation and coronary atherosclerotic burden. The results showed that there was no clear correlation between them based on computed tomography assessment.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Review
Clinical Neurology
Robert Hurford, Peter M. Rothwell
Summary: Studies have shown that intracranial atherosclerotic stenosis is more prevalent in Caucasians, especially in the elderly population. Intensive medical therapy is the preferred treatment for patients with symptomatic and asymptomatic intracranial atherosclerotic stenosis, as percutaneous stenting and angioplasty have not shown superiority over medical management.
INTERNATIONAL JOURNAL OF STROKE
(2021)
Article
Cardiac & Cardiovascular Systems
Curtis Williams, Donghee Han, Hidenobu Takagi, Christopher B. Fordyce, Stephanie Sellers, Philipp Blanke, Fay Y. Lin, Leslee J. Shaw, Sang-Eun Lee, Daniele Andreini, Mouaz H. Al-Mallah, Matthew J. Budoff, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Edoardo Conte, Hugo Marques, Pedro de Araujo Gonsalves, Ilan Gottlieb, Martin Hadamitzky, Erica Maffei, Gianluca Pontone, Sanghoon Shin, Yong-Jin Kim, Byoung Kwon Lee, Eun Ju Chun, Ji Min Sung, Renu Virmani, Habib Samady, Peter H. Stone, Daniel S. Berman, Jagat Narula, Jeroen J. Bax, Jonathon A. Leipsic, Hyuk-Jae Chang
Summary: The study aimed to investigate the effects of RAAS inhibitor on plaque progression and composition assessed by CCTA. Results showed that over nearly 4 years, RAAS inhibitor use did not significantly impact total atherosclerotic plaque progression, but there was a significant decrease in progression of non-calcified plaque in patients with a higher burden of baseline atherosclerosis.
Article
Cardiac & Cardiovascular Systems
Sara Papp, Gyoergy Barczi, Julia Karady, Marton Kolossvary, Zsofia D. Drobni, Judit Simon, Melinda Boussoussou, Borbala Vattay, Balint Szilveszter, Gyoergy Jermendy, Bela Merkely, Pal Maurovich-Horvat
Summary: The study found that the presence of myocardial bridging on the left anterior descending artery is not associated with increased plaque volumes in the LAD segment proximal to the bridging. In fact, plaque quantity was smaller in the bridging segment compared to control segments.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Bernhard Foellmer, Michelle C. C. Williams, Damini Dey, Armin Arbab-Zadeh, Pal Maurovich-Horvat, Rick H. J. A. Volleberg, Daniel Rueckert, Julia A. A. Schnabel, David E. E. Newby, Marc R. R. Dweck, Giulio Guagliumi, Volkmar Falk, Aldo J. Vazquez J. Mezquita, Federico Biavati, Ivana Isgum, Marc Dewey
Summary: In this Roadmap, Follmer et al. summarize the evidence for the application of AI technology to the imaging of vulnerable plaques in coronary arteries and discuss the current and future approaches to addressing the limitations of AI-guided coronary plaque imaging. AI has the potential to improve the assessment of images of vulnerable plaque in coronary arteries, but requires robust development, testing and validation.
NATURE REVIEWS CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Alexander Chua, Daniel Adams, Damini Dey, Ron Blankstein, Timothy Fairbairn, Jonathon Leipsic, Abdul Rahman Ihdayhid, Brian Ko
Summary: Epidemiological studies have found differences in the development of coronary artery disease between East Asians and Caucasians, with East Asians exhibiting less calcification and high-risk plaque. South Asians, on the other hand, show higher rates of coronary calcification and stenosis. Future research may clarify the prognostic value of cardiac CT in South Asians and guide preventative therapy for coronary artery disease in both East and South Asians.
Article
Cardiac & Cardiovascular Systems
Hidenobu Takagi, Jonathon A. Leipsic, Noah McNamara, Isabella Martin, Timothy A. Fairbairn, Takashi Akasaka, Bjarne L. Norgaard, Daniel S. Berman, Kavitha Chinnaiyan, Lynne M. Hurwitz-Koweek, Gianluca Pontone, Tomohiro Kawasaki, Niels Peter Ronnow Sand, Jesper M. Jensen, Tetsuya Amano, Michael Poon, Kristian A. Ovrehus, Jeroen Sonck, Mark G. Rabbat, Sarah Mullen, Bernard De Bruyne, Campbell Rogers, Hitoshi Matsuo, Jeroen J. Bax, Pamela S. Douglas, Manesh R. Patel, Koen Nieman, Abdul Rahman Ihdayhid
Summary: This study investigates the incremental value of Delta FFRCT in predicting early revascularization and improving efficiency of catheter laboratory utilization in patients with stable coronary artery disease. The results show that AFFRCT improves the discrimination of patients who underwent early revascularization compared to a standard diagnostic strategy of CCTA with FFRCT. AFFRCT has the potential to aid decision-making for ICA referral and improve efficiency of catheter laboratory utilization.
JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY
(2022)
Article
Cardiac & Cardiovascular Systems
Sean Tan, Udit Thakur, Kuan Yee Chow, Senhong Lee, Andy Ngoi, Nitesh Nerlekar, Arthur Nasis
Summary: The incidence of left ventricular thrombus after anterior ST-elevation myocardial infarction (STEMI) is 6.8%. Severe triple vessel coronary disease, apical akinesis on left ventriculogram, wrap-around LAD, and failure of recanalization after PCI are predictors for LVT formation.
CARDIOVASCULAR REVASCULARIZATION MEDICINE
(2022)
Article
Medicine, General & Internal
Sriraag Balaji Srinivasan, Amro Sehly, Biyanka Jaltotage, Simon Qin, Abdul Rahman Ihdayhid, James Marangou, James M. Rankin, Frank M. Sanfilippo, Girish Dwivedi
Summary: There is no significant difference in both bleeding and ischemic outcomes between long-term and short-term dual antiplatelet therapy for first- and second-generation drug-eluting stents in a real-world population.
IRISH JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Abdul Rahman Ihdayhid, Nick S. R. Lan, Gemma A. Figtree, Sanjay Patel, Clare Arnott, Christian Hamilton-Craig, Peter J. Psaltis, Jonathon Leipsic, Timothy Fairbairn, Sudhir Wahi, Graham S. Hillis, James M. Rankin, Girish Dwivedi, Stephen J. Nicholls
Summary: Computed tomography coronary angiography (CTCA) is an effective non-invasive diagnostic method that provides a comprehensive assessment of coronary arteries and atherosclerosis. It has been increasingly used to evaluate both stable and acute chest pain, and recent guidelines support its use as a first-line diagnostic strategy. CTCA offers advantages over functional tests in detecting coronary artery disease and guiding preventive therapies. Further studies are needed to evaluate the feasibility and cost-effectiveness of CTCA for chest pain evaluation in Australia.
HEART LUNG AND CIRCULATION
(2023)
Article
Endocrinology & Metabolism
Gavin Huangfu, Biyanka Jaltotage, Jing Pang, Nick S. R. Lan, Arun Abraham, Jacobus Otto, Abdul R. Ihdayhid, James M. Rankin, Benjamin J. W. Chow, Gerald F. Watts, Oyekoya T. Ayonrinde, Girish Dwivedi
Summary: Hepatic steatosis is associated with multiple indices of advanced coronary atherosclerosis in patients with familial hypercholesterolaemia, particularly high-risk plaque features, independent of conventional cardiovascular risk factors and markers.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2023)
Letter
Cardiac & Cardiovascular Systems
Nick S. R. Lan, Abdul Rahman Ihdayhid, Glenn Boardman, Geoff Strange, David Playford, Girish Dwivedi
ANATOLIAN JOURNAL OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Hidenobu Takagi, Abdul Rahman Ihdayhid, Jonathon A. Leipsic
Summary: Fractional flow reserve (FFR) is considered as the gold standard for revascularization decision-making in patients with stable coronary artery disease (CAD). By applying computational fluid dynamics to coronary computed tomography (CT) angiography (CCTA), FFR can be calculated without additional testing and radiation exposure, yielding FFRCT. However, integrating FFRCT into clinical practice remains a challenge due to various factors affecting FFRCT calculation and interpretation.
JOURNAL OF CARDIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Abdul Rahman Ihdayhid, Breandan Yeats, Michael Vernon, Janarthanan Sathananthan, John Webb, Jonathon Leipsic, Sharad Shetty, Vinod H. Thourani, Gerald Yong, Elena De-Juan-Pardo, Lakshmi P. Dasi
STRUCTURAL HEART-THE JOURNAL OF THE HEART TEAM
(2023)
Article
Cardiac & Cardiovascular Systems
Ciaran Kelly, Nick S. R. Lan, Jane Phan, Cherng Hng, Amy Matthews, James M. Rankin, Carl J. Schultz, Graham S. Hillis, Christopher M. Reid, Girish Dwivedi, Gemma A. Figtree, Abdul Rahman Ihdayhid
Summary: Patients with ST-elevation myocardial infarction (STEMI) without standard modifiable risk factors (SMURFS) have higher short-term mortality. The association between SMURFS and mortality in younger patients is unclear. A retrospective cohort study of young patients aged 18 to 45 years with STEMI was conducted. SMURF-less patients were more likely to have cardiac arrest, require vasopressors, mechanical support, intensive care admission, and experience left anterior descending artery infarcts. Higher mortality rates were observed in SMURF-less patients at 30 days, 1 year, and 2 years. These findings emphasize the need for improved prevention and management of SMURF-less STEMI.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Computer Science, Interdisciplinary Applications
Juan Lu, Jonathon Stewart, Mohammed Bennamoun, Adrian Goudie, Jason Eshraghian, Abdul Ihdayhid, Frank Sanfilippo, Gary R. Small, Benjamin J. W. Chow, Girish Dwivedi
Summary: Machine learning models developed using demographic and pre-test clinical information can accurately predict the results of cardiac exercise stress testing, including inconclusive or non-diagnostic results. This can help clinicians optimize the diagnostic test selection strategy for patients with coronary artery disease and reduce healthcare expenditure.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Biyanka Jaltotage, Abdul Rahman Ihdayhid, Nick S. R. Lan, Faraz Pathan, Sanjay Patel, Clare Arnott, Gemma Figtree, Leonard Kritharides, Syed Mohammed Shamsul Islam, Clara K. Chow, James M. Rankin, Stephen J. Nicholls, Girish Dwivedi
Summary: This paper provides an Australian perspective on the current state and implementation challenges of artificial intelligence in cardiology. It highlights current AI applications and emphasizes the need to address issues such as data privacy, ethical considerations, and integration with existing infrastructures.
HEART LUNG AND CIRCULATION
(2023)
Article
Medicine, General & Internal
Mikhail Alexander, Nick S. R. Lan, Michael J. Dallo, Tom G. Briffa, Frank M. Sanfilippo, Andrew Hooper, Helen Bartholomew, Loletta Hii, Graham S. Hillis, Brendan M. McQuillan, Girish Dwivedi, James M. Rankin, Abdul Rahman Ihdayhid
Summary: This study aims to examine the severity of coronary artery disease (CAD) in rural and remote Western Australian patients referred for invasive coronary angiography (ICA) in Perth and their subsequent management, and to estimate the cost savings of using computed tomography coronary angiography (CTCA) as a first line investigation. The results show that using CTCA in rural centers can avert nearly half of the referrals and is a cost-effective strategy for risk stratification of patients with suspected CAD.
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Abdul Rahman Ihdayhid, Nick S. R. Lan, Michelle Williams, David Newby, Julien Flack, Simon Kwok, Jack Joyner, Sahil Gera, Lawrence Dembo, Brendan Adler, Brian Ko, Benjamin J. W. Chow, Girish Dwivedi
Summary: This study developed and evaluated a fully automated model for identifying and quantifying coronary artery calcium (CAC). The model showed high accuracy and low analysis times, indicating its potential to optimize clinical workflow efficiency and improve patient outcomes.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Ata Doost, Thato Mabote, Richard Clugston, Abdul Rahman Ihdayhid
Summary: This case reports a large coronary perforation during IVL treatment in a patient with calcified coronary lesions. The perforation was successfully sealed with a covered stent and further imaging-guided treatment. This case highlights the importance of awareness of IVL-related complications and the potential limitation of new generation thinner-wall covered stents.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Jose E. Exaire, Timothy A. Mixon
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Giuseppe Di Gioia, Federica Coletti, Lorenzo Buzzelli, Viviana Maestrini, Sara Monosilio, Andrea Segreti, Maria Rosaria Squeo, Erika Lemme, Antonio Nenna, Antonio Pelliccia
Summary: Dyslipidemia is common in Paralympic athletes, with lipid levels influenced by the type of disability and sporting discipline.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Esra Donmez, Sevgi Ozcan, Irfan Sahin, Murat Ziyrek, Ertugrul Okuyan
Summary: This study aimed to evaluate the predictive value of the GRACE risk score in acute pulmonary embolism (PE) patients for 30-day mortality and the need for thrombolytic treatment. The study found that the GRACE risk score, along with the PESI score, were independent risk factors associated with 30-day mortality and the need for thrombolytic treatment. The GRACE risk score showed high sensitivity and specificity in predicting mortality, and its combination with the PESI score helped define high-risk PE patients and predict poor prognosis.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Tom Kai Ming Wang, Reza Reyaldeen, Kevser Akyuz, Zoran B. Popovic, A. Marc Gillinov, Bo Xu, Brian P. Griffin, Milind Y. Desai
Summary: Transthoracic echocardiography (TTE) is commonly used to evaluate isolated tricuspid regurgitation (TR), but there is limited research comparing its quantification with magnetic resonance imaging (MRI). In this study, a novel TTE algorithm was developed to identify severe TR based on TTE parameters. The algorithm had a higher accuracy than the current guidelines' criteria in detecting severe TR by MRI.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Enkhtsogt Sainbayar, Ramzi Ibrahim, Hoang Nhat Pham, Wisam Beauti, Mahek Shahid, Natalie Hickerson, Mohammed Salih, Joao Paulo Ferreira, Mamas A. Mamas
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Richard E. Casazza, Hymie Chera, Carlos Adolfo Rodriguez, Sergey Ayzenberg
Summary: This article presents a case of a patient with known situs inversus who underwent cardiac catheterization and was found to have chronic total occlusion in the right coronary artery. Situs inversus is a rare congenital abnormality characterized by the inverted position of chest and abdominal organs. Cardiac catheterization is uncommon in patients with this particular abnormality, highlighting the importance of customizing techniques to engage coronary arteries and optimize guide support for percutaneous coronary intervention if needed.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Editorial Material
Cardiac & Cardiovascular Systems
Georgiana Pintea Bentea, Brahim Berdaoui, Sophie Samyn, Marielle Morissens, Philippe van de Borne, Jose Castro Rodriguez
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Bulbul Ahmed, Melissa G. Farb, Shakun Karki, Sophia D'Alessandro, Niloo M. Edwards, Noyan Gokce
Summary: This study evaluated the angiogenic capacity of adipose tissue in patients undergoing cardiac surgeries and found that patients with coronary artery disease (CAD) had reduced angiogenic capacity in their pericardial adipose tissue. Gene expression analysis revealed upregulated expression of the anti-angiogenic gene TSP-1 in CAD patients, with no significant differences in other angiogenic factors. Additionally, inhibiting TSP-1 expression significantly improved angiogenic deficiency in CAD patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moshe Rav-Acha, Orli Wube, Oholi Tovia Brodie, Yoav Michowitz, Michael Ilan, Tal Ovdat, Robert Klempfner, Mahmud Suleiman, Ilan Goldenberg, Michael Glikson
Summary: The current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) for patients with symptomatic heart failure (HF) and low left ventricular ejection fraction. However, not all patients will benefit from ICD treatment. This study evaluated the feasibility of using the MADIT-II-based Risk Stratification Score (MRSS) to predict the survival benefit of prophylactic ICDs in patients with HF. The results showed that different risk subgroups had varying levels of ICD survival benefit.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ariel Banai, Rachel Retsky, Lior Lupu, Erez Levi, David Zahler, Omri Feder, Roei Merin, Yan Topilsky, Raphael Rosso, Shmuel Banai, Sami Viskin, Ehud Chorin
Summary: This study aims to evaluate the association between electromechanical window (EMW) and ventricular tachyarrhythmias in patients with Takotsubo syndrome (TTS). The study found that TTS patients had a lower EMW value, which was associated with an increased risk of ventricular tachyarrhythmias.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Harun Kundi, Kobina Hagan, Tamer Yahya, Garima Sharma, Sadeer Al-Kindi, Zulqarnain Javed, Khurram Nasir
Summary: Using latent class analysis (LCA), the study identified clinical, demographic, and social subphenotypes in ASCVD population and assessed the risk of all-cause and cardiovascular mortality across different socioclinical classes. The results showed that the younger, female, non-Hispanic Black or Hispanic individuals with a high burden of co-morbidities and unfavorable social determinants of health had the highest risk of mortality in the identified latent classes.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Moises A. Vasquez, Mina Iskander, Mohammed Mustafa, Juan A. Quintero-Martinez, Antonio Luna, Joel Mintz, Jose Noy, Juan Uribe, Ivan Mijares, Eduardo de Marchena, Yiannis S. Chatzizisis
Summary: The benefits of pericardiocentesis (PC) in patients with pulmonary hypertension (PH) and pericardial effusions are unclear. The study found that PC in PH patients is associated with higher in-hospital mortality and rates of cardiovascular complications.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ken Kuwajima, Mana Ogawa, Irving Ruiz, Hiroko Hasegawa, Nobuichiro Yagi, Florian Rader, Robert J. Siegel, Takahiro Shiota
Summary: After cardiac surgery, the longitudinal function of the right ventricle and left ventricle is reduced, despite preserved global functions. In particular, tricuspid annular plane systolic excursion (TAPSE) remains decreased after surgery.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Min -Jung Kim, Robert H. Aseltine Jr, Sara R. Tabtabai
Summary: This study evaluated the rates and causes of 30-day readmissions after discharge for heart failure (HF) as a primary and secondary diagnosis. The findings indicate that efforts to reduce readmission rates should include patients with secondary HF diagnosis, and surveillance should extend to 2 weeks postdischarge to identify at-risk patients.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)
Article
Cardiac & Cardiovascular Systems
Ya He, Jianzhong Zhou
Summary: This study aimed to examine the relation between reverse septal curvature (RSC) and nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM). The study found that patients with RSC were younger and had a higher incidence of NSVT, and RSC was identified as a strong independent risk factor for NSVT.
AMERICAN JOURNAL OF CARDIOLOGY
(2024)