Early‐onset aging and mitochondrial defects associated with loss of histone acetyltransferase 1 (Hat1)

Epigenetic effects of metformin: From molecular mechanisms to clinical implications

(2018) Stephanie Claire Bridgeman et al.   DIABETES OBESITY & METABOLISM

Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice

(2018) Shrestha Ghosh et al.   eLife

Identification of multiple roles for histone acetyltransferase 1 in replication-coupled chromatin assembly

(2017) Paula A. Agudelo Garcia et al.   NUCLEIC ACIDS RESEARCH

AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1

(2017) Traci L. Marin et al.   Science Signaling

AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1

(2017) Traci L. Marin et al.   Science Signaling

The world of protein acetylation

(2016) Adrian Drazic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Epigenetic Mechanisms of Longevity and Aging

(2016) Payel Sen et al.   CELL

Mouse models of ageing and their relevance to disease

(2016) Sulev Kõks et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mechanisms and Dynamics of Protein Acetylation in Mitochondria

(2016) Josue Baeza et al.   TRENDS IN BIOCHEMICAL SCIENCES

Pathology of Mouse Models of Accelerated Aging

(2016) L. Harkema et al.   VETERINARY PATHOLOGY

Decline in Weight and Incident Mild Cognitive Impairment

(2016) Rabe E. Alhurani et al.   JAMA Neurology

Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging

(2016) Rui-Hong Wang et al.   Scientific Reports

Epigenetic regulation of ageing: linking environmental inputs to genomic stability

(2015) Bérénice A. Benayoun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SIRT3 regulates progression and development of diseases of aging

(2015) Eoin McDonnell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF

(2015) Anthony J. Sadler et al.   Nature Communications

The growing landscape of lysine acetylation links metabolism and cell signalling

(2014) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deletion of atrophy enhancing genes fails to ameliorate the phenotype in a mouse model of spinal muscular atrophy

(2014) Chitra C. Iyer et al.   NEUROMUSCULAR DISORDERS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Mice as a Mammalian Model for Research on the Genetics of Aging

(2013) R. Yuan et al.   ILAR JOURNAL

FoxP3 Acts as a Cotranscription Factor with STAT3 in Tumor-Induced Regulatory T Cells

(2013) Dewan Md Sakib Hossain et al.   IMMUNITY

Histone Acetyltransferase 1 Promotes Homologous Recombination in DNA Repair by Facilitating Histone Turnover

(2013) Xiaohan Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sites of Acetylation on Newly Synthesized Histone H4 Are Required for Chromatin Assembly and DNA Damage Response Signaling

(2013) Zhongqi Ge et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone Acetyl Transferase 1 Is Essential for Mammalian Development, Genome Stability, and the Processing of Newly Synthesized Histones H3 and H4

(2013) Prabakaran Nagarajan et al.   PLoS Genetics

SIRT3 Is a Mitochondrial Tumor Suppressor: A Scientific Tale That Connects Aberrant Cellular ROS, the Warburg Effect, and Carcinogenesis

(2012) M. C. Haigis et al.   CANCER RESEARCH

Mechanistic insights into the regulation of metabolic enzymes by acetylation

(2012) Yue Xiong et al.   JOURNAL OF CELL BIOLOGY

The histone acetyltransferase Hat1 facilitates DNA damage repair and morphogenesis inCandida albicans

(2012) Michael Tscherner et al.   MOLECULAR MICROBIOLOGY

Nuclear Hat1p Complex (NuB4) Components Participate in DNA Repair-linked Chromatin Reassembly

(2011) Zhongqi Ge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Physical and Biological Characterization of a Frail Mouse Model

(2011) J. Walston et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes

(2011) Mohan Viswanathan et al.   NATURE

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

(2011) F. G. Osorio et al.   Science Translational Medicine

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

(2010) Q. Wang et al.   SCIENCE

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated

(2008) Shao H. Yang et al.   JOURNAL OF CLINICAL INVESTIGATION