Viral Regulation of RNA Granules in Infected Cells

RNA granules associated with SAMD9-mediated poxvirus restriction are similar to antiviral granules in composition but do not require TIA1 for poxvirus restriction

(2019) Xiangzhi Meng et al.   VIROLOGY

Essential role of enterovirus 2A protease in counteracting stress granule formation and the induction of type I interferon

(2019) Linda J. Visser et al.   JOURNAL OF VIROLOGY

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies

(2018) Ji-Young Youn et al.   MOLECULAR CELL

Picornavirus 2A protease regulates stress granule formation to facilitate viral translation

(2018) Xiaodan Yang et al.   PLoS Pathogens

Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs

(2018) Zhulong Hu et al.   PLoS Pathogens

Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms

(2018) Xu Ye et al.   Frontiers in Immunology

Human host-range restriction of the vaccinia virus C7/K1 double deletion mutant is mediated by an atypical mode of translation inhibition

(2018) Gilad Sivan et al.   JOURNAL OF VIROLOGY

Rotavirus RNAs sponge host cell RNA binding proteins and interfere with their subcellular localization

(2018) Alfonso Oceguera et al.   VIROLOGY

Stress Granules and Processing Bodies in Translational Control

(2018) Pavel Ivanov et al.   Cold Spring Harbor Perspectives in Biology

Zika Virus Hijacks Stress Granule Proteins and Modulates the Host Stress Response

(2017) Shangmei Hou et al.   JOURNAL OF VIROLOGY

P-Body Purification Reveals the Condensation of Repressed mRNA Regulons

(2017) Arnaud Hubstenberger et al.   MOLECULAR CELL

Multivalent Recruitment of Human Argonaute by GW182

(2017) Elad Elkayam et al.   MOLECULAR CELL

Moloney leukemia virus 10 (MOV10) inhibits the degradation of APOBEC3G through interference with the Vif-mediated ubiquitin–proteasome pathway

(2017) Cancan Chen et al.   Retrovirology

Ebola virus VP35 blocks stress granule assembly

(2017) Valerie Le Sage et al.   VIROLOGY

Functional organization of cytoplasmic inclusion bodies in cells infected by respiratory syncytial virus

(2017) Vincent Rincheval et al.   Nature Communications

KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation

(2017) Nishi R. Sharma et al.   PLoS Pathogens

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

Arginine Demethylation of G3BP1 Promotes Stress Granule Assembly

(2016) Wei-Chih Tsai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanistic insights into mammalian stress granule dynamics

(2016) Marc D. Panas et al.   JOURNAL OF CELL BIOLOGY

G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

(2016) Nancy Kedersha et al.   JOURNAL OF CELL BIOLOGY

MOV10 Provides Antiviral Activity against RNA Viruses by Enhancing RIG-I–MAVS-Independent IFN Induction

(2016) Rolando A. Cuevas et al.   JOURNAL OF IMMUNOLOGY

LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner

(2016) Tian-Tian Liu et al.   JOURNAL OF IMMUNOLOGY

Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus Mutants

(2016) Ruikang Liu et al.   JOURNAL OF VIROLOGY

Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions

(2016) Emily V. Nelson et al.   JOURNAL OF VIROLOGY

Human Cytomegalovirus pTRS1 and pIRS1 Antagonize Protein Kinase R To Facilitate Virus Replication

(2016) Benjamin Ziehr et al.   JOURNAL OF VIROLOGY

Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage

(2016) Majid N. Humoud et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 2 Virion Host Shutoff Endoribonuclease Activity Is Required To Disrupt Stress Granule Formation

(2016) Renée L. Finnen et al.   JOURNAL OF VIROLOGY

The Herpes Simplex Virus Virion Host Shutoff Protein Enhances Translation of Viral True Late mRNAs Independently of Suppressing Protein Kinase R and Stress Granule Formation

(2016) Bianca Dauber et al.   JOURNAL OF VIROLOGY

Principles and Properties of Stress Granules

(2016) David S.W. Protter et al.   TRENDS IN CELL BIOLOGY

Who Regulates Whom? An Overview of RNA Granules and Viral Infections

(2016) Natalia Poblete-Durán et al.   Viruses-Basel

NEDDylation promotes stress granule assembly

(2016) Aravinth Kumar Jayabalan et al.   Nature Communications

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

(2016) Huib H. Rabouw et al.   PLoS Pathogens

Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories

(2016) Jovan Nikolic et al.   PLoS Pathogens

Distinct stages in stress granule assembly and disassembly

(2016) Joshua R Wheeler et al.   eLife

Dengue virus infection induces formation of G3BP1 granules in human lung epithelial cells

(2015) Jun Xia et al.   ARCHIVES OF VIROLOGY

Stress granules, P-bodies and cancer

(2015) Paul Anderson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Dynamic Interaction of Stress Granules, DDX3X, and IKK-α Mediates Multiple Functions in Hepatitis C Virus Infection

(2015) Véronique Pène et al.   JOURNAL OF VIROLOGY

Virus-induced translational arrest through 4EBP1/2-dependent decay of 5′-TOP mRNAs restricts viral infection

(2015) Kaycie C. Hopkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rotavirus disrupts cytoplasmic P bodies during infection

(2015) Rahul Bhowmick et al.   VIRUS RESEARCH

Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1

(2015) Lucas C. Reineke et al.   mBio

Viral Activation of MK2-hsp27-p115RhoGEF-RhoA Signaling Axis Causes Cytoskeletal Rearrangements, P-body Disruption and ARE-mRNA Stabilization

(2015) Jennifer A. Corcoran et al.   PLoS Pathogens

The Herpes Simplex Virus 2 Virion-Associated Ribonuclease vhs Interferes with Stress Granule Formation

(2014) R. L. Finnen et al.   JOURNAL OF VIROLOGY

Activation of Stress Response Pathways Promotes Formation of Antiviral Granules and Restricts Virus Replication

(2014) D. K. Rozelle et al.   MOLECULAR AND CELLULAR BIOLOGY

Processing bodies accumulate in human cytomegalovirus-infected cells and do not affect viral replication at high multiplicity of infection

(2014) Eri Seto et al.   VIROLOGY

Mov10 and APOBEC3G Localization to Processing Bodies Is Not Required for Virion Incorporation and Antiviral Activity

(2013) T. Izumi et al.   JOURNAL OF VIROLOGY

The Virion Host Shutoff RNase Plays a Key Role in Blocking the Activation of Protein Kinase R in Cells Infected with Herpes Simplex Virus 1

(2013) M. T. Sciortino et al.   JOURNAL OF VIROLOGY

Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses

(2013) C. S. Ng et al.   JOURNAL OF VIROLOGY

Inactivation of the mTORC1-Eukaryotic Translation Initiation Factor 4E Pathway Alters Stress Granule Formation

(2013) M.-J. Fournier et al.   MOLECULAR AND CELLULAR BIOLOGY

The HIV-1 Nef Protein Binds Argonaute-2 and Functions as a Viral Suppressor of RNA Interference

(2013) Madeeha Aqil et al.   PLoS One

Production of a Dominant-Negative Fragment Due to G3BP1 Cleavage Contributes to the Disruption of Mitochondria-Associated Protective Stress Granules during CVB3 Infection

(2013) Gabriel Fung et al.   PLoS One

Stress granules and cell signaling: more than just a passing phase?

(2013) Nancy Kedersha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dynamic Oscillation of Translation and Stress Granule Formation Mark the Cellular Response to Virus Infection

(2012) Alessia Ruggieri et al.   Cell Host & Microbe

Both G3BP1 and G3BP2 contribute to stress granule formation

(2012) Hideaki Matsuki et al.   GENES TO CELLS

HIV-1 Gag co-opts a cellular complex containing DDX6, a helicase that facilitates capsid assembly

(2012) Jonathan C. Reed et al.   JOURNAL OF CELL BIOLOGY

Inclusion Bodies Are a Site of Ebolavirus Replication

(2012) T. Hoenen et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 2 Infection Impacts Stress Granule Accumulation

(2012) R. L. Finnen et al.   JOURNAL OF VIROLOGY

Blocking Double-Stranded RNA-Activated Protein Kinase PKR by Japanese Encephalitis Virus Nonstructural Protein 2A

(2012) Y.-C. Tu et al.   JOURNAL OF VIROLOGY

The NS1 Protein of Influenza A Virus Interacts with Cellular Processing Bodies and Stress Granules through RNA-Associated Protein 55 (RAP55) during Virus Infection

(2012) B. W.-Y. Mok et al.   JOURNAL OF VIROLOGY

p38 and OGT Sequestration into Viral Inclusion Bodies in Cells Infected with Human Respiratory Syncytial Virus Suppresses MK2 Activities and Stress Granule Assembly

(2012) Jens Fricke et al.   JOURNAL OF VIROLOGY

Induction of Stress Granule-Like Structures in Vesicular Stomatitis Virus-Infected Cells

(2012) P. X. Dinh et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus (HCV) Induces Formation of Stress Granules Whose Proteins Regulate HCV RNA Replication and Virus Assembly and Egress

(2012) U. Garaigorta et al.   JOURNAL OF VIROLOGY

Stress Granule Formation Induced by Measles Virus Is Protein Kinase PKR Dependent and Impaired by RNA Adenosine Deaminase ADAR1

(2012) K. M. Okonski et al.   JOURNAL OF VIROLOGY

Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules

(2012) Ken Fujimura et al.   NUCLEIC ACIDS RESEARCH

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

(2012) Koji Onomoto et al.   PLoS One

Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells

(2012) G. Clavarino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of stress granules in virus systems

(2012) James P. White et al.   TRENDS IN MICROBIOLOGY

Recruitment of host translation initiation factor eIF4G by the Vaccinia Virus ssDNA-binding protein I3

(2012) Izabela Zaborowska et al.   VIROLOGY

P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication

(2012) Harendra S. Chahar et al.   VIROLOGY

P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation

(2012) C. J. Decker et al.   Cold Spring Harbor Perspectives in Biology

Influenza A virus inhibits cytoplasmic stress granule formation

(2011) Denys A. Khaperskyy et al.   FASEB JOURNAL

Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs

(2011) H. M. Burgess et al.   JOURNAL OF CELL SCIENCE

Junin virus infection impairs stress-granule formation in Vero cells treated with arsenite via inhibition of eIF2  phosphorylation

(2011) F. N. Linero et al.   JOURNAL OF GENERAL VIROLOGY

Hepatitis C Virus Hijacks P-Body and Stress Granule Components around Lipid Droplets

(2011) Y. Ariumi et al.   JOURNAL OF VIROLOGY

The Leader Protein of Cardioviruses Inhibits Stress Granule Assembly

(2011) F. Borghese et al.   JOURNAL OF VIROLOGY

Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm

(2011) Anthony K.L. Leung et al.   MOLECULAR CELL

Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3’ UTR structures

(2011) Alex Michael Ward et al.   RNA Biology

The adenovirus E4 11k protein binds and relocalizes the cytoplasmic P-body component Ddx6 to aggresomes

(2011) Amy E. Greer et al.   VIROLOGY

Activation of protein kinase R is required for induction of stress granules by respiratory syncytial virus but dispensable for viral replication

(2011) Michael E. Lindquist et al.   VIROLOGY

Poly(A)-binding protein (PABP): a common viral target

(2010) Richard W. P. Smith et al.   BIOCHEMICAL JOURNAL

Sindbis Virus Usurps the Cellular HuR Protein to Stabilize Its Transcripts and Promote Productive Infections in Mammalian and Mosquito Cells

(2010) Kevin J. Sokoloski et al.   Cell Host & Microbe

RNA granules: The good, the bad and the ugly

(2010) María Gabriela Thomas et al.   CELLULAR SIGNALLING

Viral Double-stranded RNAs from Vaccinia Virus Early or Intermediate Gene Transcripts Possess PKR Activating Function, Resulting in NF-κB Activation, When the K1 Protein Is Absent or Mutated

(2010) Kristen L. Willis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Staufen1 ribonucleoproteins prevent formation of stress granules but favour encapsidation of HIV-1 genomic RNA

(2010) L. G. Abrahamyan et al.   JOURNAL OF CELL SCIENCE

Regulation of PKR by HCV IRES RNA: Importance of Domain II and NS5A

(2010) Rebecca Toroney et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein Kinase R Is Responsible for the Phosphorylation of eIF2α in Rotavirus Infection

(2010) Margarito Rojas et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus Induces Host RNA Stress Granules To Facilitate Viral Replication

(2010) M. E. Lindquist et al.   JOURNAL OF VIROLOGY

Modulation of Stress Granules and P Bodies during Dicistrovirus Infection

(2010) A. Khong et al.   JOURNAL OF VIROLOGY

An RNA Pseudoknot Is Required for Production of Yellow Fever Virus Subgenomic RNA by the Host Nuclease XRN1

(2010) P. A. G. C. Silva et al.   JOURNAL OF VIROLOGY

Formation of Antiviral Cytoplasmic Granules during Orthopoxvirus Infection

(2010) M. Simpson-Holley et al.   JOURNAL OF VIROLOGY

P Body-Associated Protein Mov10 Inhibits HIV-1 Replication at Multiple Stages

(2010) R. Burdick et al.   JOURNAL OF VIROLOGY

Poliovirus-Mediated Disruption of Cytoplasmic Processing Bodies

(2010) J. D. Dougherty et al.   JOURNAL OF VIROLOGY

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Perturbation of the P-Body Component Mov10 Inhibits HIV-1 Infectivity

(2010) Vyacheslav Furtak et al.   PLoS One

Protein Expression Redirects Vesicular Stomatitis Virus RNA Synthesis to Cytoplasmic Inclusions

(2010) Bianca S. Heinrich et al.   PLoS Pathogens

RNA Dimerization Promotes PKR Dimerization and Activation

(2009) Laurie A. Heinicke et al.   JOURNAL OF MOLECULAR BIOLOGY

Functional Characterization of Negri Bodies (NBs) in Rabies Virus-Infected Cells: Evidence that NBs Are Sites of Viral Transcription and Replication

(2009) X. Lahaye et al.   JOURNAL OF VIROLOGY

NSs Protein of Rift Valley Fever Virus Induces the Specific Degradation of the Double-Stranded RNA-Dependent Protein Kinase

(2009) M. Habjan et al.   JOURNAL OF VIROLOGY

P-Body Components Are Required for Ty1 Retrotransposition during Assembly of Retrotransposition-Competent Virus-Like Particles

(2009) M. A. Checkley et al.   MOLECULAR AND CELLULAR BIOLOGY

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

Cellular MicroRNA and P Bodies Modulate Host-HIV-1 Interactions

(2009) Robin Nathans et al.   MOLECULAR CELL

RNA granules: post-transcriptional and epigenetic modulators of gene expression

(2009) Paul Anderson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rift Valley Fever Virus NSs Protein Promotes Post-Transcriptional Downregulation of Protein Kinase PKR and Inhibits eIF2α Phosphorylation

(2009) Tetsuro Ikegami et al.   PLoS Pathogens

Expression of poly(A)-binding protein is upregulated during recovery from heat shock in HeLa cells

(2008) Shuhua Ma et al.   FEBS Journal

Sendai Virus C Protein Plays a Role in Restricting PKR Activation by Limiting the Generation of Intracellular Double-Stranded RNA

(2008) K. Takeuchi et al.   JOURNAL OF VIROLOGY

Different Types of nsP3-Containing Protein Complexes in Sindbis Virus-Infected Cells

(2008) R. Gorchakov et al.   JOURNAL OF VIROLOGY

Storage of cellular 5' mRNA caps in P bodies for viral cap-snatching

(2008) M. A. Mir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Multiple Pathways Differentially Regulate Global Oxidative Stress Responses in Fission Yeast

(2007) Dongrong Chen et al.   MOLECULAR BIOLOGY OF THE CELL