Design and Characterization of Inulin Conjugate for Improved Intracellular and Targeted Delivery of Pyrazinoic Acid to Monocytes

Investigation of the biodistribution, breakdown and excretion of delta inulin adjuvant

(2017) Lixin Wang et al.   VACCINE

Delta inulin-based adjuvants promote the generation of polyfunctional CD4+ T cell responses and protection against Mycobacterium tuberculosis infection

(2017) Claudio Counoupas et al.   Scientific Reports

Immunotherapy – 2076. A controlled study of delta inulin-adjuvanted honey bee venom immunotherapy

(2017) Robert Heddle et al.   World Allergy Organization Journal

Physical characterization and in silico modeling of inulin polymer conformation during vaccine adjuvant particle formation

(2016) Thomas G. Barclay et al.   CARBOHYDRATE POLYMERS

Understanding dissemination of Mycobacterium tuberculosis from the lungs during primary infection

(2016) Michelle B. Ryndak et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Tumor microenvironment and intracellular signal-activated nanomaterials for anticancer drug delivery

(2016) Ran Mo et al.   Materials Today

Bioreducible heparin-based nanogel drug delivery system

(2015) Wei Wu et al.   BIOMATERIALS

Mechanisms of Drug Release in Nanotherapeutic Delivery Systems

(2015) Pamela T. Wong et al.   CHEMICAL REVIEWS

Monocyte targeting and activation by cationic liposomes formulated with a TLR7 agonist

(2015) Pia T Johansen et al.   Expert Opinion on Drug Delivery

Inulin as a novel biocompatible coating: Evaluation of surface affinities toward CaHPO 4 , α-Fe 2 O 3 , ZnO, CaHPO 4 @ZnO and α-Fe 2 O 3 @ZnO nanoparticles

(2015) E. Santillán-Urquiza et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Spray Dried Aerosol Particles of Pyrazinoic Acid Salts for Tuberculosis Therapy

(2015) P. G. Durham et al.   MOLECULAR PHARMACEUTICS

Macrophage activation in human diseases

(2015) Joachim L. Schultze et al.   SEMINARS IN IMMUNOLOGY

Prospects in Mycobacterium bovis Bacille Calmette et Guérin (BCG) vaccine diversity and delivery: Why does BCG fail to protect against tuberculosis?

(2015) Juan I. Moliva et al.   VACCINE

Design Strategies and Applications of Circulating Cell-Mediated Drug Delivery Systems

(2015) Yixue Su et al.   ACS Biomaterials-Science & Engineering

Design Strategies and Applications of Circulating Cell-Mediated Drug Delivery Systems

(2015) Yixue Su et al.   ACS Biomaterials Science & Engineering

Simulated Biological Fluids with Possible Application in Dissolution Testing

(2015) Margareth R. C. Marques et al.   DISSOLUTION TECHNOLOGIES

Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model

(2014) V. Torraca et al.   Disease Models & Mechanisms

Evolved gas analysis (coupled TG–DSC–FTIR) applied to the thermal behaviour of inulin

(2014) Roberta de Souza Leone et al.   JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS

Immunogenicity and safety of Advax™, a novel polysaccharide adjuvant based on delta inulin, when formulated with hepatitis B surface antigen: A randomized controlled Phase 1 study

(2014) David Gordon et al.   VACCINE

A computational study of pyrazinamide: Tautomerism, acid–base properties, micro-solvation effects and acid hydrolysis mechanism

(2014) Mwadham M. Kabanda et al.   Computational and Theoretical Chemistry

The polysaccharide inulin is characterized by an extensive series of periodic isoforms with varying biological actions

(2013) P. D. Cooper et al.   GLYCOBIOLOGY

DNA-Catalyzed Hydrolysis of Esters and Aromatic Amides

(2013) Benjamin M. Brandsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis, Antimycobacterial Activity and In Vitro Cytotoxicity of 5-Chloro-N-phenylpyrazine-2-carboxamides

(2013) Jan Zitko et al.   MOLECULES

Grafting of model primary amine compounds to cellulose nanowhiskers through periodate oxidation

(2012) Rajalaxmi Dash et al.   CELLULOSE

Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic influenza vaccine containing Advax™ polysaccharide adjuvant

(2012) David L. Gordon et al.   VACCINE

Advax™, a polysaccharide adjuvant derived from delta inulin, provides improved influenza vaccine protection through broad-based enhancement of adaptive immune responses

(2012) Yoshikazu Honda-Okubo et al.   VACCINE

Macrophage-Specific Targeting of Isoniazid Through Mannosylated Gelatin Microspheres

(2011) Sanjay Tiwari et al.   AAPS PHARMSCITECH

HIV and Tuberculosis: a Deadly Human Syndemic

(2011) C. K. Kwan et al.   CLINICAL MICROBIOLOGY REVIEWS

Cell-mediated drug delivery

(2011) Elena V Batrakova et al.   Expert Opinion on Drug Delivery

Inulin and poly(acrylic acid) grafted inulin for dissolution enhancement and preliminary controlled release of poorly water-soluble Irbesartan drug

(2011) Mohammad M. Fares et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells

(2011) Liang Chen et al.   NANOTECHNOLOGY

Pyrazinamide Polymorphs: Relative Stability and Vibrational Spectroscopy

(2010) Suryanarayan Cherukuvada et al.   CRYSTAL GROWTH & DESIGN

Delta inulin: a novel, immunologically active, stable packing structure comprising  -D-[2 -> 1] poly(fructo-furanosyl)  -D-glucose polymers

(2010) P. D. Cooper et al.   GLYCOBIOLOGY

An inactivated Vero cell-grown Japanese encephalitis vaccine formulated with Advax, a novel inulin-based adjuvant, induces protective neutralizing antibody against homologous and heterologous flaviviruses

(2010) M. Lobigs et al.   JOURNAL OF GENERAL VIROLOGY

Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

(2010) Samuel M. Behar et al.   NATURE REVIEWS MICROBIOLOGY

Insight on the periodate oxidation of dextran and its structural vicissitudes

(2010) João Maia et al.   POLYMER

Hydroxyapatite nano and microparticles: Correlation of particle properties with cytotoxicity and biostability

(2009) M. Motskin et al.   BIOMATERIALS

Physicochemical studies on the biopolymer inulin: A critical evaluation of its self-aggregation, aggregate-morphology, interaction with water, and thermal stability

(2009) Abhijit Dan et al.   BIOPOLYMERS

Effect of surface charge and agglomerate degree of magnetic iron oxide nanoparticles on KB cellular uptake in vitro

(2009) Yuqing Ge et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Lipophilic pyrazinoic acid amide and ester prodrugs

(2009) Marta Filipa Simões et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

NanoART synthesis, characterization, uptake, release and toxicology for human monocyte–macrophage drug delivery

(2009) Ari S Nowacek et al.   Nanomedicine

The influence of surface functionalization on the enhanced internalization of magnetic nanoparticles in cancer cells

(2009) Angeles Villanueva et al.   NANOTECHNOLOGY

Evasion and subversion of antigen presentation byMycobacterium tuberculosis

(2009) A. Baena et al.   TISSUE ANTIGENS

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

(2008) Pascale Peyron et al.   PLoS Pathogens