Biodistribution and Physiologically-Based Pharmacokinetic Modeling of Gold Nanoparticles in Mice with Interspecies Extrapolation

Synthesis of curcumin-functionalized gold nanoparticles and cytotoxicity studies in human prostate cancer cell line

(2018) Shruti Nambiar et al.   Applied Nanoscience

Application of Physiologically Based Pharmacokinetic Modeling to Predict the Effects of FcRn Inhibitors in Mice, Rats, and Monkeys

(2018) Tommy Li et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Population PBPK modelling of trastuzumab: a framework for quantifying and predicting inter-individual variability

(2017) Paul R. V. Malik et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim

(2017) Christoph Niederalt et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Physiologically Based Pharmacokinetic (PBPK) Modeling of Pharmaceutical Nanoparticles

(2016) Min Li et al.   AAPS Journal

Physiologically based pharmacokinetic models of small molecules and therapeutic antibodies: a mini-review on fundamental concepts and applications

(2016) Gregory Z. Ferl et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Toward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticles

(2016) Ulrika Carlander et al.   International Journal of Nanomedicine

The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction

(2016) Nazanin Hoshyar et al.   Nanomedicine

A Review of Clinical Translation of Inorganic Nanoparticles

(2015) Aaron C. Anselmo et al.   AAPS Journal

Biomedical Applications of Gold Nanoparticles

(2015) Daniela Cabuzu et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Nanoparticle uptake: The phagocyte problem

(2015) Heather Herd Gustafson et al.   Nano Today

Predicting the impact of biocorona formation kinetics on interspecies extrapolations of nanoparticle biodistribution modeling

(2015) Faryad Darabi Sahneh et al.   Nanomedicine

A physiologically based pharmacokinetic model for polyethylene glycol-coated gold nanoparticles of different sizes in adult mice

(2015) Zhoumeng Lin et al.   Nanotoxicology

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

A versatile pipeline for the multi-scale digital reconstruction and quantitative analysis of 3D tissue architecture

(2015) Hernán Morales-Navarrete et al.   eLife

Gold and silver nanoparticle interactions with human proteins: impact and implications in biocorona formation

(2015) Abhilash Sasidharan et al.   Journal of Materials Chemistry B

Structural Study of Citrate Layers on Gold Nanoparticles: Role of Intermolecular Interactions in Stabilizing Nanoparticles

(2014) Jong-Won Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Short- and long-term distribution and toxicity of gold nanoparticles in the rat after a single-dose intravenous administration

(2014) Sónia Fraga et al.   Nanomedicine-Nanotechnology Biology and Medicine

Synthesis of metallic nanoparticles using plant extracts

(2013) Amit Kumar Mittal et al.   BIOTECHNOLOGY ADVANCES

A physiologically based pharmacokinetic model for ionic silver and silver nanoparticles

(2013) von Goetz et al.   International Journal of Nanomedicine

Of mice, men and nanoparticle biocoronas: arein vitrotoin vivocorrelations and interspecies extrapolations realistic?

(2013) Jim E Riviere   Nanomedicine

Curcumin conjugated gold nanoparticle synthesis and its biocompatibility

(2013) K. Sindhu et al.   RSC Advances

Evaluation of a Catenary PBPK Model for Predicting the In Vivo Disposition of mAbs Engineered for High-Affinity Binding to FcRn

(2012) Yang Chen et al.   AAPS Journal

Physiologically Based Pharmacokinetic Model for Composite Nanodevices: Effect of Charge and Size on In Vivo Disposition

(2012) Donald E. Mager et al.   PHARMACEUTICAL RESEARCH

Particle size-dependent and surface charge-dependent biodistribution of gold nanoparticles after intravenous administration

(2011) Stephanie Hirn et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human

(2011) Dhaval K. Shah et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods

(2010) Yang Qiu et al.   BIOMATERIALS

Biodistribution and toxicity of engineered gold nanoparticles: a review of in vitro and in vivo studies

(2010) Nikolai Khlebtsov et al.   CHEMICAL SOCIETY REVIEWS

Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?

(2010) Alaaldin M. Alkilany et al.   JOURNAL OF NANOPARTICLE RESEARCH

Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide

(2010) Simon Guerrero et al.   Nanomedicine

Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats

(2009) Suresh K. Balasubramanian et al.   BIOMATERIALS

Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity

(2009) Elodie Boisselier et al.   CHEMICAL SOCIETY REVIEWS

Cellular organization of normal mouse liver: a histological, quantitative immunocytochemical, and fine structural analysis

(2009) Janie L. Baratta et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

(2008) Michelle Longmire et al.   Nanomedicine