Statins Do Not Directly Inhibit the Activity of Major Epigenetic Modifying Enzymes

Epigenetic effects of metformin: From molecular mechanisms to clinical implications

(2018) Stephanie Claire Bridgeman et al.   DIABETES OBESITY & METABOLISM

Statins use and cancer: an update

(2018) Martyna Zaleska et al.   Future Oncology

Cancer epigenetics and the potential of epigenetic drugs for treating solid tumors

(2018) Zhenghui Liu et al.   Expert Review of Anticancer Therapy

Statins and risk of cancer: A meta-analysis of randomized, double-blind, placebo-controlled trials

(2017) SK Myung et al.   INDIAN JOURNAL OF CANCER

Effects of statins on cancer mortality and progression: A systematic review and meta-analysis of 95 cohorts including 1,111,407 individuals

(2017) Zubing Mei et al.   INTERNATIONAL JOURNAL OF CANCER

Pleiotropic and Adverse Effects of Statins—Do Epigenetics Play a Role?

(2017) Stephanie C. Allen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Statins and risk of cancer: A meta-analysis of randomized, double-blind, placebo-controlled trials

(2017) SK Myung et al.   INDIAN JOURNAL OF CANCER

Greater efficacy of atorvastatin versus a non-statin lipid-lowering agent against renal injury: potential role as a histone deacetylase inhibitor

(2016) Ravi Shankar Singh et al.   Scientific Reports

Tissue specific up regulation of ACE2 in rabbit model of atherosclerosis by atorvastatin: Role of epigenetic histone modifications

(2015) Kulbhushan Tikoo et al.   BIOCHEMICAL PHARMACOLOGY

Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents

(2015) Madhusoodanan Mottamal et al.   MOLECULES

Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells

(2015) Heidrun Karlic et al.   Cancer Genetics

Cardiovascular Risk and Statin Use in the United States

(2014) M. E. Johansen et al.   ANNALS OF FAMILY MEDICINE

Obesity and diabetes: from genetics to epigenetics

(2014) Ernesto Burgio et al.   MOLECULAR BIOLOGY REPORTS

Design and Synthesis of Dual-Action Inhibitors Targeting Histone Deacetylases and 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase for Cancer Treatment

(2013) Jhih-Bin Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comparative benefits of statins in the primary and secondary prevention of major coronary events and all-cause mortality: a network meta-analysis of placebo-controlled and active-comparator trials

(2013) Huseyin Naci et al.   European Journal of Preventive Cardiology

What is a relevant statin concentration in cell experiments claiming pleiotropic effects?

(2011) Linda Björkhem-Bergman et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Epigenetic modifications in cancer

(2011) R Kanwal et al.   CLINICAL GENETICS

Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway

(2011) L. L. Kodach et al.   GUT

Statins Promote the Regression of Atherosclerosis via Activation of the CCR7-Dependent Emigration Pathway in Macrophages

(2011) Jonathan E. Feig et al.   PLoS One

When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts

(2010) Mariona Jové et al.   Lipids in Health and Disease

Epigenetics and cardiovascular disease

(2010) José M. Ordovás et al.   Nature Reviews Cardiology

Curcumin is a potent DNA hypomethylation agent

(2008) Zhongfa Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Statins Increase p21 through Inhibition of Histone Deacetylase Activity and Release of Promoter-Associated HDAC1/2

(2008) Y.-C. Lin et al.   CANCER RESEARCH

Zn(II)-dependent histone deacetylase inhibitors: Suberoylanilide hydroxamic acid and trichostatin A

(2008) Rachel Codd et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY